type 2 diabetes mellitus
Findings
No curated finding names type 2 diabetes mellitus yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.
Definition from the Mondo Disease Ontology (MONDO:0005148), read 2026-09-29. CC BY 4.0.
Features
1 feature
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, hp/releases/2026-09-01.
- Insulin resistanceMondoHP:0000855
Genes
18 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- ABCC8HGNC:59
- Strong · Genomics England PanelApp · Autosomal dominant · 2021
- Limited · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2017
- AKT2HGNC:392
- Strong · Genomics England PanelApp · Autosomal dominant · 2021
- Limited · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2017
- GCKHGNC:4195
- Strong · Genomics England PanelApp · Autosomal dominant · 2020
- Strong · PanelApp Australia · Autosomal dominant · 2025
- HNF1AHGNC:11621
- Strong · Genomics England PanelApp · Autosomal dominant · 2021
Where it sits
- A kind of
Other names
23 names
Resolves to: type 2 diabetes mellitus
- Also called
- adult onset diabetesadult-onset diabetesdiabetes mellitis type 2diabetes mellitis type IIdiabetes mellitus, noninsulin-dependentdiabetes mellitus, noninsulin-dependent, association withdiabetes mellitus, noninsulin-dependent, late onsetdiabetes mellitus, type 2diabetes mellitus, type IIdiabetes, type 2insulin resistance, severe, digenicNIDDMnon-insulin dependent diabetesnon-insulin dependent diabetes mellitusnoninsulin dependent diabetes