Compound
1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine
A lysophosphatidylcholine 18:2 in which the acyl group at position 1 is (9Z,12Z)-octadecadienoyl.
Definition from ChEBI (CHEBI:28733), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound
- Formula
- C26H50NO7P
- Mass
- 519.66 g/mol
- Charge
- 0
- InChIKey
- SPJFYYJXNPEZDW-FTJOPAKQSA-N
- SMILES
- CCCCC/C=CC/C=CCCCCCCCC(=O)OC[C@@H](O)COP(=O)([O-])OCC[N+](C)(C)C
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
7 entities
7 entities reached.
0 reported hops7 assembled from the scaffold
- ATP8B1ProteinUNIPROT:O43520transported byInferred only81 paths79 endpoints
- ABCA1ProteinUNIPROT:O95477transported byInferred only47 paths47 endpoints
- PLAAT3ProteinUNIPROT:P53816substrate ofInferred only11 paths11 endpoints
- ABCB4ProteinUNIPROT:P21439transported byInferred only8 paths7 endpoints
- ENPP2ProteinUNIPROT:Q13822substrate ofInferred only5 paths5 endpoints
- ENPP6ProteinUNIPROT:Q6UWR7substrate ofInferred only5 paths5 endpoints
- ATP8B2ProteinUNIPROT:P98198transported byInferred only3 paths3 endpoints
What the reference databases state
Chemical structure
- 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine has the functional parent linoleic acidCompoundChEBI CHEBI:28733Inferred only
Statements
8 statements
8 statements · 2 reference databases · Subject: 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine · Sources: Human-GEM, Rhea
- 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine is a substrate of ENPP2ProteinRhea RHEA:41135Inferred only
- 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine is a substrate of ENPP6ProteinRhea RHEA:41115Inferred only
- 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine is a substrate of PLAAT3ProteinRhea RHEA:56428Inferred only
- 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine is transported by ABCA1ProteinHuman-GEM MAR11596Inferred only
- 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine is transported by ABCB4ProteinHuman-GEM MAR11596Inferred only
- 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine is transported by ATP10AProteinHuman-GEM MAR11596Inferred only
- 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine is transported by ATP8B1ProteinHuman-GEM MAR11596Inferred only
- 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine is transported by ATP8B2ProteinHuman-GEM MAR11596Inferred only
Reactions
10 reactions
1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR10279CC BY 4.0Reference data
ATP+water+1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholineADP+proton+phosphate(3-)+1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine
Transported by ABCB4 or ATP8B1 or ATP8B2 or ABCA1 or ATP10A
Reaction pageLeft to rightBalancedEC 7.6.2.2, 7.6.2.1GO:0005829, GO:0005615
Human-GEM MAR11596CC BY 4.0Reference data
1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine
Reaction pageLeft to rightBalancedEC 7.6.2.2, 7.6.2.1GO:0005615, GO:0005829
Human-GEM MAR11661CC BY 4.0Reference data
1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine+water1-(9Z,12Z-octadecadienoyl)-sn-glycerol+phosphocholine+hydron
Catalysed by ENPP6
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:41115CC BY 4.0Reference data
1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine+water1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate+choline+hydron
Catalysed by ENPP2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:41135CC BY 4.0Reference data
1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine+water1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine+(9Z,12Z)-octadecadienoate+hydron
Catalysed by PLAAT3
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:56428CC BY 4.0Reference data
1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine+1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine+1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:67432CC BY 4.0Reference data
1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine+1-tetradecanoyl-sn-glycero-3-phosphocholine1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine+1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:67436CC BY 4.0Reference data
1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine+1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine+1',3'-bis-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:67456CC BY 4.0Reference data
CHEBI:173223+1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine+1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:67768CC BY 4.0Reference data
Where it reaches
10 systems, 25 regions, 85 tissues, 86 transporter routes — routes, not measurements: transporters known to carry 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine are expressed there, and no source reports it arriving.
Loading the model…
Other names
42 names
Resolves to: 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine
- Also called
- 1-(9Z,12Z-octadecadienoyl)-glycero-3-phosphocholine1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine1-18:2-lysoPC1-Linoleoyl-glycero-3-phosphocholine1-linoleoyl-GPC1-linoleoyl-GPC (18:2)1-linoleoyl-phosphatidylcholine1-Linoleoyl-sn-glycero-3-phosphocholine1-Linoleoyl-sn-glycero-3-phosphorylcholine1-Linoleoylglycerophosphocholine18:2 LYSO-PCGPC(18:2)GPC(18:2/0:0)LPC 18:2LPC 18:2(9Z,12Z)/0:0LPC(18:2)LPC(18:2/0:0)LPC(18:2n6/0:0)LPC(18:2omega6/0:0)LPC(18:2ω6/0:0)LyPC(18:2)LyPC(18:2n6/0:0)LyPC(18:2omega6/0:0)LyPC(18:2ω6/0:0)LysoPC 18:2(9Z,12Z)/0:0LysoPC(18:2(9Z,12Z)/0:0)LysoPC(18:2)LysoPC(18:2/0:0)LysoPC(18:2n6/0:0)LysoPC(18:2omega6/0:0)LysoPC(18:2ω6/0:0)lysophosphatidylcholine(18:2(9Z,12Z)/0:0)Lysophosphatidylcholine(18:2)Lysophosphatidylcholine(18:2/0:0)Lysophosphatidylcholine(18:2n6/0:0)Lysophosphatidylcholine(18:2omega6/0:0)Lysophosphatidylcholine(18:2ω6/0:0)PC 18:2(9Z,12Z)/0:0PC(18:2(9Z,12Z)/0:0)PC(18:2/0:0)
- Systematic name
- (2R)-2-hydroxy-3-[(9Z,12Z)-octadeca-9,12-dienoyloxy]propyl 2-(trimethylammonio)ethyl phosphate(2R)-2-hydroxy-3-[(9Z,12Z)-octadeca-9,12-dienoyloxy]propyl 2-(trimethylazaniumyl)ethyl phosphate