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Proteins/UNIPROT:Q9ULL4
Receptor for SEMA5A that plays a role in axon guidance, invasive growth and cell migration. Stimulates neurite outgrowth and mediates Ca(2+)/Mg(2+)-dependent cell aggregation. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1..
Function from UniProtKB (Q9ULL4), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
28 statements
28 statements · 3 reference databases · Subject: PLXNB3 · Sources: gene ontology, Hetionet, Reactome
3 names
Resolves to: PLXNB3