a 1,2-diacyl-sn-glycerol

1. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
2. an N-acyl-(4R)-4-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acyl-(4R)-4-hydroxysphinganine-phosphocholine + a 1,2-diacyl-sn-glycerol

Catalysed by SGMS1, SGMS2One of 2 routes

1. CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
2. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = N-hexadecanoyl-sphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol

Catalysed by SELENOI, CEPT1, SGMS2, SAMD8One of 2 routes

1. CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
2. an N-acylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acylsphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol

Catalysed by SELENOI, CEPT1, SGMS2, SAMD8One of 2 routes

1. CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
2. N-hexadecanoyl-(4R)-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = N-hexadecanoyl-(4R)-hydroxysphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol

Catalysed by SELENOI, CEPT1, SGMS2, SAMD8One of 2 routes

1. CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
2. an N-acyl-(4R)-4-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol

Catalysed by SELENOI, CEPT1, SGMS2, SAMD8One of 2 routes

1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O

Catalysed by SGMS1, SGMS2, ASAH2

1. 1,2-diacyl-sn-glycerol acylhydrolase
2. (10Z)-heptadecenoic acid formation

Catalysed by LPLextracellular spaceOne of 12 routes

1. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
2. 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine = 1,2-dihexadecanoyl-sn-glycerol + a sphingomyelin

Catalysed by SGMS1, SGMS2

1. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
2. 1-(9Z-octadecenoyl)-2-acyl-sn-3-glycerol + a sphingomyelin = a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine

Catalysed by SGMS1, SGMS2

1. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
2. a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a monoacyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)

Catalysed by SGMS1, SGMS2, PNLIPRP2

1. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
2. an N-acylethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 2-(acylamino)ethyl fatty acid + a 2-acyl-sn-glycero-3-phosphocholine

Catalysed by SGMS1, SGMS2, PLA2G15One of 2 routes

1. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
2. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine

Catalysed by SGMS1, SGMS2, PLA2G15One of 4 routes

1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (physeteric acid)

Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 8 routes

1. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
2. ethanol + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1,2-diacyl-sn-glycero-3-phosphoethanol + choline

Catalysed by SGMS1, SGMS2, PLD1

1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial

Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 5 morecytosol, mitochondrial matrix

1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. acetyl-CoA C-acyltransferase (3-oxo-4(R),8-dimethyl-nonanoyl-CoA)

Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 4 morecytosol, mitochondrial matrix

1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)

Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 8 routes

1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (tricosanoic acid)

Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 4 routes

1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. glycine N-acyltransferase (N-arachidonoylglycine)
3. N(omega)-methyl-L-arginine + glyoxylate = 5-(3-methylguanidino)-2-oxopentanoate + glycine

Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 5 morecytosol, mitochondrial matrixOne of 2 routes

1. 1,2-diacyl-sn-glycerol acylhydrolase
2. (10Z)-heptadecenoic acid formation
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + 2 O2 = prostaglandin H2 + A + H2O