Compound

(2E)-decenoyl-CoA

An acyl-CoA oxoanion arising from deprotonation of the phosphate and diphosphate OH groups of trans-dec-2-enoyl-CoA; major species at pH 7.3.

Definition from ChEBI (CHEBI:61406), read 2026-09-23. CC BY 4.0.

CHEBI:61406ChEBI

Open in the graph

Structure

2D depiction

No three-dimensional record for this entry.

Class: Organic compound, anion
Formula: C31H48N7O17P3S
Mass: 915.746 g/mol
Charge: -4
InChIKey: MGNBGCRQQFMNBM-YJHHLLFWSA-J
SMILES: CCCCCCC/C=C/C(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-]
Look it up: ChEBI By InChIKey

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

8 entities

8 entities reached.

0 reported hops8 assembled from the scaffold

What the reference databases state

Statements

33 statements

33 statements · 2 reference databases · Subject: (2E)-decenoyl-CoA · Sources: Human-GEM, Rhea

Order

(2E)-decenoyl-CoA is converted to (3E)-decenoyl-CoACompoundHuman-GEM MAR03323Inferred only
(3E)-decenoyl-CoA is converted to (2E)-decenoyl-CoACompoundHuman-GEM MAR03323Inferred only
(3E)-decenoyl-CoA is converted to (2E)-decenoyl-CoACompoundHuman-GEM MAR03298Inferred only
(3E)-decenoyl-CoA is converted to (2E)-decenoyl-CoACompoundRhea RHEA:45752Inferred only
(2E)-decenoyl-CoA is converted to (3E)-decenoyl-CoACompoundHuman-GEM MAR03298Inferred only
(3Z)-decenoyl-CoA is converted to (2E)-decenoyl-CoACompoundRhea RHEA:77195Inferred only
decanoyl-CoA is converted to (2E)-decenoyl-CoACompoundHuman-GEM MAR02187Inferred only
decanoyl-CoA is converted to (2E)-decenoyl-CoACompoundHuman-GEM MAR03090Inferred only
decanoyl-CoA is converted to (2E)-decenoyl-CoACompoundHuman-GEM MAR03142Inferred only
decanoyl-CoA is converted to (2E)-decenoyl-CoACompoundRhea RHEA:40179Inferred only
(2E)-decenoyl-CoA is converted to decanoyl-CoACompoundHuman-GEM MAR02187Inferred only
(2E)-decenoyl-CoA is converted to decanoyl-CoACompoundRhea RHEA:44960Inferred only

Show the remaining 21

decanoyl-CoA is converted to (2E)-decenoyl-CoACompoundRhea RHEA:28354Inferred only
(2E)-decenoyl-CoA is converted to decanoyl-CoACompoundRhea RHEA:28354Inferred only
(2E)-decenoyl-CoA is a substrate of ACAA1ProteinHuman-GEM MAR04968Inferred only
(2E)-decenoyl-CoA is a substrate of ECHS1ProteinHuman-GEM MAR03143Inferred only
(2E)-decenoyl-CoA is a substrate of ECHS1ProteinRhea RHEA:31191Inferred only
(2E)-decenoyl-CoA is a substrate of ECI1ProteinHuman-GEM MAR03298Inferred only
(2E)-decenoyl-CoA is a substrate of ECI1ProteinHuman-GEM MAR03323Inferred only
(2E)-decenoyl-CoA is a substrate of ECI2ProteinHuman-GEM MAR03323Inferred only
(2E)-decenoyl-CoA is a substrate of ECI2ProteinHuman-GEM MAR03298Inferred only
(2E)-decenoyl-CoA is a substrate of EHHADHProteinRhea RHEA:31191Inferred only
(2E)-decenoyl-CoA is a substrate of EHHADHProteinHuman-GEM MAR03091Inferred only
(2E)-decenoyl-CoA is a substrate of EHHADHProteinHuman-GEM MAR04968Inferred only
(2E)-decenoyl-CoA is a substrate of EHHADHProteinHuman-GEM MAR03323Inferred only
(2E)-decenoyl-CoA is a substrate of HADHAProteinHuman-GEM MAR03323Inferred only
(2E)-decenoyl-CoA is a substrate of HADHAProteinHuman-GEM MAR03143Inferred only
(2E)-decenoyl-CoA is a substrate of HADHAProteinRhea RHEA:31191Inferred only
(2E)-decenoyl-CoA is a substrate of HSD17B4ProteinHuman-GEM MAR04968Inferred only
(2E)-decenoyl-CoA is a substrate of HSD17B4ProteinHuman-GEM MAR03091Inferred only
(2E)-decenoyl-CoA is a substrate of HSD17B4ProteinRhea RHEA:45992Inferred only
(2E)-decenoyl-CoA is a substrate of MECRProteinHuman-GEM MAR02187Inferred only
(2E)-decenoyl-CoA is a substrate of PECRProteinRhea RHEA:44960Inferred only

Reactions

20 reactions

decanoyl-CoA+NADP(3-)(2E)-decenoyl-CoA+proton+NADPH(4-)
Catalysed by MECR
Reaction pageReversibleBalancedEC 1.3.1.38mitochondrial matrix
Human-GEM MAR02187CC BY 4.0Reference data
decanoyl-CoA+FAD(2E)-decenoyl-CoA+FADH2
Catalysed by ACOX3 or ACOX1
Reaction pageLeft to rightBalancedEC 1.3.3.6peroxisome
Human-GEM MAR03090CC BY 4.0Reference data
(2E)-decenoyl-CoA+waterMAM00181x
Catalysed by EHHADH or HSD17B4
Reaction pageLeft to rightBalancedEC 4.2.1.17peroxisome
Human-GEM MAR03091CC BY 4.0Reference data
decanoyl-CoA+FAD(2E)-decenoyl-CoA+FADH2
Catalysed by ACOX3 or ACOX1 or ACADM or ACAD9
Reaction pageLeft to rightBalancedEC 1.3.8.7, 1.3.99.-, 1.3.3.6mitochondrial matrix
Human-GEM MAR03142CC BY 4.0Reference data
(2E)-decenoyl-CoA+waterMAM00181m
Catalysed by HADHA or ECHS1
Reaction pageLeft to rightBalancedEC 4.2.1.17mitochondrial matrix
Human-GEM MAR03143CC BY 4.0Reference data
(2E)-decenoyl-CoA(3E)-decenoyl-CoA
Catalysed by ECI1 or ECI2
Reaction pageReversibleBalancedEC 5.3.3.8mitochondrial matrix
Human-GEM MAR03298CC BY 4.0Reference data
(2E)-decenoyl-CoA(3E)-decenoyl-CoA
Catalysed by ECI2 & HADHA & ECI1 & EHHADH
Reaction pageReversibleBalancedEC 5.3.3.8peroxisome
Human-GEM MAR03323CC BY 4.0Reference data
(2E)-decenoyl-CoA+CHEBI:1146900+water+NAD(+)CHEBI:15351+proton+NADH(2-)+octanoyl-CoA
Catalysed by ACAA1 & HSD17B4 & EHHADH
Reaction pageLeft to rightBalancedperoxisome
Human-GEM MAR04968CC BY 4.0Reference data
decanoyl-CoA+FAD(3-)+hydron(2E)-decenoyl-CoA+FADH2(2-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:28354CC BY 4.0Reference data
CHEBI:62616(2E)-decenoyl-CoA+water
Catalysed by ECHS1 or HADHA or EHHADH
Reaction pageRight to leftBalanced
Rhea RHEA:31191CC BY 4.0Reference data
decanoyl-CoA+dioxygen(2E)-decenoyl-CoA+hydrogen peroxide
Catalysed by ACOX3 or ACOX1 or ACOX2
Reaction pageLeft to rightBalanced
Rhea RHEA:40179CC BY 4.0Reference data
(2E)-decenoyl-CoA+NADPH(4-)+hydrondecanoyl-CoA+NADP(3-)
Catalysed by PECR
Reaction pageLeft to rightBalanced
Rhea RHEA:44960CC BY 4.0Reference data

Show the remaining 8

Other names

4 names

Resolves to: (2E)-decenoyl-CoA

Also called: trans-2-decenoyl-coenzyme A tetraaniontrans-2,3-didehydroacyl-CoA (C10)(4-)trans-2,3-didehydroacyl-CoA (C10)(4−)trans-dec-2-enoyl-CoA tetraanion