Proteins/UNIPROT:Q6S5L8

SHC4

ProteinUNIPROT:Q6S5L8

Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1..

Function from UniProtKB (Q6S5L8), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

51 statements

51 statements · 2 reference databases · Subject: SHC4 · Sources: Hetionet, WikiPathways

Order

DNAAF4 covaries with SHC4ProteinHetionet hetionet:covaries:161582-399694Inferred only
HEXIM2 covaries with SHC4ProteinHetionet hetionet:covaries:124790-399694Inferred only
GRB2 interacts with SHC4ProteinHetionet hetionet:interacts:2885-399694Inferred only
SHC4 participates in Brain derived neurotrophic factor BDNF signalingPathwayWikiPathways WP2380Inferred only
SHC4 participates in Breast cancer pathwayPathwayWikiPathways WP4262Inferred only
SHC4 participates in Chemokine signalingPathwayWikiPathways WP3929Inferred only
SHC4 participates in Effect of dasatinib on the BCR ABL signaling pathwayPathwayWikiPathways WP5493Inferred only
SHC4 participates in EGFR tyrosine kinase inhibitor resistancePathwayWikiPathways WP4806Inferred only
SHC4 participates in ErbB signalingPathwayWikiPathways WP673Inferred only
SHC4 participates in Focal adhesionPathwayWikiPathways WP306Inferred only
SHC4 participates in Ras signalingPathwayWikiPathways WP4223Inferred only
SHC4 increases the expression of ABCC5ProteinHetionet hetionet:regulates:399694-10057Inferred only

Show the remaining 39

SHC4 decreases the expression of ADI1ProteinHetionet hetionet:regulates:399694-55256Inferred only
SHC4 increases the expression of CADM1ProteinHetionet hetionet:regulates:399694-23705Inferred only
SHC4 decreases the expression of CDC20ProteinHetionet hetionet:regulates:399694-991Inferred only
SHC4 increases the expression of CEMIP2ProteinHetionet hetionet:regulates:399694-23670Inferred only
SHC4 decreases the expression of CPNE3ProteinHetionet hetionet:regulates:399694-8895Inferred only
SHC4 increases the expression of CRIP1ProteinHetionet hetionet:regulates:399694-1396Inferred only
SHC4 decreases the expression of CSRP1ProteinHetionet hetionet:regulates:399694-1465Inferred only
SHC4 increases the expression of DDIT4ProteinHetionet hetionet:regulates:399694-54541Inferred only
SHC4 increases the expression of E2F2ProteinHetionet hetionet:regulates:399694-1870Inferred only
SHC4 decreases the expression of ENOPH1ProteinHetionet hetionet:regulates:399694-58478Inferred only
SHC4 increases the expression of FOXO3ProteinHetionet hetionet:regulates:399694-2309Inferred only
SHC4 increases the expression of FZD7ProteinHetionet hetionet:regulates:399694-8324Inferred only
SHC4 decreases the expression of GNASProteinHetionet hetionet:regulates:399694-2778Inferred only
SHC4 decreases the expression of GRWD1ProteinHetionet hetionet:regulates:399694-83743Inferred only
SHC4 decreases the expression of HACD3ProteinHetionet hetionet:regulates:399694-51495Inferred only
SHC4 increases the expression of HMGA2ProteinHetionet hetionet:regulates:399694-8091Inferred only
SHC4 decreases the expression of IFRD2ProteinHetionet hetionet:regulates:399694-7866Inferred only
SHC4 decreases the expression of INTS3ProteinHetionet hetionet:regulates:399694-65123Inferred only
SHC4 increases the expression of MCOLN1ProteinHetionet hetionet:regulates:399694-57192Inferred only
SHC4 decreases the expression of MIFProteinHetionet hetionet:regulates:399694-4282Inferred only
SHC4 decreases the expression of NOLC1ProteinHetionet hetionet:regulates:399694-9221Inferred only
SHC4 decreases the expression of PABPC4ProteinHetionet hetionet:regulates:399694-8761Inferred only
SHC4 decreases the expression of PGAM1ProteinHetionet hetionet:regulates:399694-5223Inferred only
SHC4 increases the expression of PLA2G15ProteinHetionet hetionet:regulates:399694-23659Inferred only
SHC4 increases the expression of PLCB3ProteinHetionet hetionet:regulates:399694-5331Inferred only
SHC4 decreases the expression of PLS1ProteinHetionet hetionet:regulates:399694-5357Inferred only
SHC4 decreases the expression of POP4ProteinHetionet hetionet:regulates:399694-10775Inferred only
SHC4 decreases the expression of RPIAProteinHetionet hetionet:regulates:399694-22934Inferred only
SHC4 increases the expression of SATB1ProteinHetionet hetionet:regulates:399694-6304Inferred only
SHC4 increases the expression of SELLProteinHetionet hetionet:regulates:399694-6402Inferred only
SHC4 decreases the expression of SGCBProteinHetionet hetionet:regulates:399694-6443Inferred only
SHC4 decreases the expression of TARBP1ProteinHetionet hetionet:regulates:399694-6894Inferred only
SHC4 decreases the expression of TP53BP1ProteinHetionet hetionet:regulates:399694-7158Inferred only
SHC4 decreases the expression of TP53BP2ProteinHetionet hetionet:regulates:399694-7159Inferred only
SHC4 decreases the expression of TSPAN6ProteinHetionet hetionet:regulates:399694-7105Inferred only
SHC4 decreases the expression of TXNDC9ProteinHetionet hetionet:regulates:399694-10190Inferred only
SHC4 decreases the expression of UBE3CProteinHetionet hetionet:regulates:399694-9690Inferred only
SHC4 decreases the expression of UGDHProteinHetionet hetionet:regulates:399694-7358Inferred only
SHC4 decreases the expression of WDR12ProteinHetionet hetionet:regulates:399694-55759Inferred only

Other names

7 names

Resolves to: SHC4

Also called: hShcDRai-like proteinRaLPSH2 domain protein C4SHC-transforming protein DSHCDSrc homology 2 domain-containing-transforming protein C4

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