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Proteins/UNIPROT:Q13362
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment. The PP2A-PPP2R5C holoenzyme may specifically dephosphorylate and activate TP53 and play a role in DNA damage-induced inhibition of cell proliferation. PP2A-PPP2R5C may also regulate the ERK signaling pathway through ERK dephosphorylation..
Function from UniProtKB (Q13362), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
124 statements
124 statements · 4 reference databases · Subject: PPP2R5C · Sources: gene ontology, Hetionet, Reactome, WikiPathways
6 names
Resolves to: PPP2R5C