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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Proteins/UNIPROT:Q96I23

PYURF

Protein·UNIPROT:Q96I23

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In mitochondria, S-adenosylmethionine-dependent methyltransferase chaperone that supports both coenzyme Q biosynthesis, by stabilizing its components, such as COQ5, and NADH:ubiquinone oxidoreductase complex (complex I, MT-ND1) assembly, by stabilizing complex I assembly factors, such as NDUFAF5..

Function from UniProtKB (Q96I23), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

8 statements

8 statements · 2 reference databases · Subject: PYURF · Sources: Human-GEM, Reactome

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PYURF participates in Aerobic respiration and respiratory electron transportPathwayReactome R-HSA-1428517Inferred only
PYURF participates in Complex I biogenesisPathwayReactome R-HSA-6799198Inferred only
PYURF participates in MetabolismPathwayReactome R-HSA-1430728Inferred only
PYURF participates in Respiratory electron transportPathwayReactome R-HSA-611105Inferred only
1-phosphatidyl-1D-myo-inositol is a substrate of PYURFCompoundHuman-GEM MAR07185Inferred only
1-phosphatidyl-1D-myo-inositol is a substrate of PYURFCompoundHuman-GEM MAR08379Inferred only
CHEBI:16264 is a substrate of PYURFCompoundHuman-GEM MAR08379Inferred only
CHEBI:16264 is a substrate of PYURFCompoundHuman-GEM MAR07185Inferred only

Reactions

2 reactions

1-phosphatidyl-1D-myo-inositol+CHEBI:16264proton+a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol+UDP
Catalysed by PIGA & PIGH & PIGC & PIGQ or PYURF or PIGP or PIGY
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.198endoplasmic reticulum
Human-GEM MAR07185CC BY 4.0Reference data
1-phosphatidyl-1D-myo-inositol

Other names

5 names

Resolves to: PYURF

Also called: NDUFAFQPIGY upstream reading frame proteinPREYpreY, mitochondrialProtein preY, mitochondrial

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+a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol

Catalysed by PIGA & PIGH & PIGC & PIGQ or PYURF or PIGP or PIGY

Reaction pageLeft to rightBalance undeterminableEC 2.4.1.198cytosol

Human-GEM MAR08379CC BY 4.0Reference data