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Proteins/UNIPROT:Q96HZ4
Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. Promotes cell differentiation (By similarity)..
Function from UniProtKB (Q96HZ4), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
56 statements
56 statements · 3 reference databases · Subject: HES6 · Sources: gene ontology, Hetionet, WikiPathways
4 names
Resolves to: HES6