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Proteins/UNIPROT:Q9UD57
Transcriptional repressor. May play a role in early development as a Wnt/beta-catenin effector, hence controlling pluripotency and preimplantation development of embryonic stem cells. May promote adipogenesis in mesenchymal stem cells, possibly by inhibiting the expression of the antiadipogenic factor NR2F2. May inhibit osteoblastogenic differentiation..
Function from UniProtKB (Q9UD57), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
69 statements
69 statements · 2 reference databases · Subject: NKX1-2 · Sources: gene ontology, Hetionet
4 names
Resolves to: NKX1-2