Proteins/UNIPROT:Q9H161

ALX4

ProteinUNIPROT:Q9H161

Transcription factor involved in skull and limb development. Plays an essential role in craniofacial development, skin and hair follicle development..

Function from UniProtKB (Q9H161), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

4 rows

craniosynostosis 5, susceptibility to has a germline basis in ALX4DiseaseGenCC HGNC:450|MONDO:0014232Inferred only
frontonasal dysplasia with alopecia and genital anomaly has a germline basis in ALX4DiseaseGenCC HGNC:450|MONDO:0013268Inferred only
parietal foramina has a germline basis in ALX4DiseaseGenCC HGNC:450|MONDO:0018953Inferred only
parietal foramina 2 has a germline basis in ALX4DiseaseGenCC HGNC:450|MONDO:0012309Inferred only

Statements

22 statements

22 statements · 3 reference databases · Subject: ALX4 · Sources: gene ontology, Hetionet, WikiPathways

Order

ABI3 covaries with ALX4ProteinHetionet hetionet:covaries:51225-60529Inferred only
AMER1 covaries with ALX4ProteinHetionet hetionet:covaries:139285-60529Inferred only
CYRIA covaries with ALX4ProteinHetionet hetionet:covaries:60529-81553Inferred only
EXOC3L1 covaries with ALX4ProteinHetionet hetionet:covaries:283849-60529Inferred only
NKX1-2 covaries with ALX4ProteinHetionet hetionet:covaries:390010-60529Inferred only
OR13C8 covaries with ALX4ProteinHetionet hetionet:covaries:138802-60529Inferred only
OR1L6 covaries with ALX4ProteinHetionet hetionet:covaries:392390-60529Inferred only
TSEN34 covaries with ALX4ProteinHetionet hetionet:covaries:60529-79042Inferred only
ALX1 interacts with ALX4ProteinHetionet hetionet:interacts:60529-8092Inferred only
CEBPE interacts with ALX4ProteinHetionet hetionet:interacts:1053-60529Inferred only
EMX1 interacts with ALX4ProteinHetionet hetionet:interacts:2016-60529Inferred only
FOXA3 interacts with ALX4ProteinHetionet hetionet:interacts:3171-60529Inferred only

Show the remaining 10

GATA4 interacts with ALX4ProteinHetionet hetionet:interacts:2626-60529Inferred only
HOXA3 interacts with ALX4ProteinHetionet hetionet:interacts:3200-60529Inferred only
HOXB13 interacts with ALX4ProteinHetionet hetionet:interacts:10481-60529Inferred only
HOXB6 interacts with ALX4ProteinHetionet hetionet:interacts:3216-60529Inferred only
HOXD3 interacts with ALX4ProteinHetionet hetionet:interacts:3232-60529Inferred only
LEF1 interacts with ALX4ProteinHetionet hetionet:interacts:51176-60529Inferred only
SOX10 interacts with ALX4ProteinHetionet hetionet:interacts:60529-6663Inferred only
SOX2 interacts with ALX4ProteinHetionet hetionet:interacts:60529-6657Inferred only
ALX4 participates in 11p11 2 copy number variation syndrome PathwayWikiPathways WP5348Inferred only
ALX4 regulates regulation of transcription by RNA polymerase IIBiological processgene ontology Q9H161|GO:0006357Inferred only

Other names

2 names

Resolves to: ALX4

Also called: Homeobox protein aristaless-like 4KIAA1788

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