inflammatory bowel disease 25
Findings
No curated finding names inflammatory bowel disease 25 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any inflammatory bowel disease in which the cause of the disease is a mutation in the IL10RB gene.
Definition from the Mondo Disease Ontology (MONDO:0012941), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal recessive inheritance
- Onset and course
- Infantile onset
HPO, annotations 2026-09-02
Features
7 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- EnterocolitisHPOHP:0004387
- 2 of 2 reported patients · Infantile onset
- FolliculitisHPOHP:0025084
- 2 of 2 reported patients · Infantile onset
- 1 of 1 reported patient
- PancolitisHPOHP:0033256
- 1 of 1 reported patient
- Rectovaginal fistulaHPOHP:0000143
- 1 of 1 reported patient · Infantile onset · Female
- Recurrent bronchitisHPOHP:0002837
- 1 of 1 reported patient
- Enterocutaneous fistulaHPOHP:0033279
- 1 of 2 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- IL10RBHGNC:5965
- Definitive · ClinGen · Autosomal recessive · 2024
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal recessive · 2020
- Strong · PanelApp Australia · Autosomal recessive · 2025
Where it sits
Other names
5 names
Resolves to: inflammatory bowel disease 25
- Also called
- IBD25IL10RB inflammatory bowel diseaseinflammatory bowel disease 25, early onset, autosomal recessiveinflammatory bowel disease caused by mutation in IL10RBinflammatory bowel disease type 25