Proteins/UNIPROT:Q6NUQ1

RINT1

ProteinUNIPROT:Q6NUQ1

Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER. May play a role in cell cycle checkpoint control. Essential for telomere length control..

Function from UniProtKB (Q6NUQ1), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

3 rows

hereditary spastic paraplegia has a germline basis in RINT1DiseaseGenCC HGNC:21876|MONDO:0019064Inferred only
infantile liver failure syndrome 2 has a germline basis in RINT1DiseaseGenCC HGNC:21876|MONDO:0014659Inferred only
infantile liver failure syndrome 3 has a germline basis in RINT1DiseaseGenCC HGNC:21876|MONDO:0032844Inferred only

Statements

27 statements

27 statements · 3 reference databases · Subject: RINT1 · Sources: gene ontology, Hetionet, Reactome

Order

RINT1 covaries with HMGN4ProteinHetionet hetionet:covaries:10473-60561Inferred only
OR6T1 covaries with RINT1ProteinHetionet hetionet:covaries:219874-60561Inferred only
BNIP3L interacts with RINT1ProteinHetionet hetionet:interacts:60561-665Inferred only
GFI1B interacts with RINT1ProteinHetionet hetionet:interacts:60561-8328Inferred only
RAD50 interacts with RINT1ProteinHetionet hetionet:interacts:10111-60561Inferred only
RB1 interacts with RINT1ProteinHetionet hetionet:interacts:5925-60561Inferred only
RBL1 interacts with RINT1ProteinHetionet hetionet:interacts:5933-60561Inferred only
RBL2 interacts with RINT1ProteinHetionet hetionet:interacts:5934-60561Inferred only
SPTBN1 interacts with RINT1ProteinHetionet hetionet:interacts:60561-6711Inferred only
UBC interacts with RINT1ProteinHetionet hetionet:interacts:60561-7316Inferred only
XPNPEP1 interacts with RINT1ProteinHetionet hetionet:interacts:60561-7511Inferred only
ZW10 interacts with RINT1ProteinHetionet hetionet:interacts:60561-9183Inferred only

Show the remaining 15

RINT1 participates in COPI-dependent Golgi-to-ER retrograde trafficPathwayReactome R-HSA-6811434Inferred only
RINT1 participates in Golgi-to-ER retrograde transportPathwayReactome R-HSA-8856688Inferred only
RINT1 participates in Intra-Golgi and retrograde Golgi-to-ER trafficPathwayReactome R-HSA-6811442Inferred only
RINT1 participates in Membrane TraffickingPathwayReactome R-HSA-199991Inferred only
RINT1 participates in Vesicle-mediated transportPathwayReactome R-HSA-5653656Inferred only
RINT1 regulates regulation of ER to Golgi vesicle-mediated transportBiological processgene ontology Q6NUQ1|GO:0060628Inferred only
ARG1 increases the expression of RINT1ProteinHetionet hetionet:regulates:383-60561Inferred only
CHERP decreases the expression of RINT1ProteinHetionet hetionet:regulates:10523-60561Inferred only
DLD decreases the expression of RINT1ProteinHetionet hetionet:regulates:1738-60561Inferred only
IDH2 decreases the expression of RINT1ProteinHetionet hetionet:regulates:3418-60561Inferred only
LSM5 increases the expression of RINT1ProteinHetionet hetionet:regulates:23658-60561Inferred only
PGAM1 increases the expression of RINT1ProteinHetionet hetionet:regulates:5223-60561Inferred only
PLOD3 decreases the expression of RINT1ProteinHetionet hetionet:regulates:8985-60561Inferred only
PTMS increases the expression of RINT1ProteinHetionet hetionet:regulates:5763-60561Inferred only
STAT3 increases the expression of RINT1ProteinHetionet hetionet:regulates:6774-60561Inferred only

Other names

3 names

Resolves to: RINT1

Also called: HsRINT-1RAD50 interactor 1RINT-1

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