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Proteins/UNIPROT:Q96CH1
G protein-coupled receptor required for the regulation of plasma cholesterol levels. Receptor for CHLSN, a gut derived hormone which mediates an inhibitory effect of intestinal cholesterol absorption on hepatic cholesterol synthesis. Cholesin-binding exerts an antagonistic effect by inhibiting PKA signaling and suppressing SREBF2-controlled cholesterol in the liver..
Function from UniProtKB (Q96CH1), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
64 statements
64 statements · 2 reference databases · Subject: GPR146 · Sources: gene ontology, Hetionet
3 names
Resolves to: GPR146