Proteins/UNIPROT:Q01538

MYT1

ProteinUNIPROT:Q01538

Binds to the promoter region of genes encoding proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendroglia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription..

Function from UniProtKB (Q01538), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

oculoauriculovertebral spectrum with radial defects has a germline basis in MYT1DiseaseGenCC HGNC:7622|MONDO:0007712Inferred only

Statements

23 statements

23 statements · 3 reference databases · Subject: MYT1 · Sources: gene ontology, Hetionet, WikiPathways

Order

MYT1 covaries with CDH4ProteinHetionet hetionet:covaries:1002-4661Inferred only
CYP2W1 covaries with MYT1ProteinHetionet hetionet:covaries:4661-54905Inferred only
FAM193A covaries with MYT1ProteinHetionet hetionet:covaries:4661-8603Inferred only
GPR146 covaries with MYT1ProteinHetionet hetionet:covaries:115330-4661Inferred only
MYT1 covaries with KCNQ2ProteinHetionet hetionet:covaries:3785-4661Inferred only
KLC1 covaries with MYT1ProteinHetionet hetionet:covaries:3831-4661Inferred only
MYT1 covaries with LSM7ProteinHetionet hetionet:covaries:4661-51690Inferred only
MYT1 covaries with PGBD2ProteinHetionet hetionet:covaries:267002-4661Inferred only
SMARCC1 covaries with MYT1ProteinHetionet hetionet:covaries:4661-6599Inferred only
SNTG1 covaries with MYT1ProteinHetionet hetionet:covaries:4661-54212Inferred only
CDK1 interacts with MYT1ProteinHetionet hetionet:interacts:4661-983Inferred only
MYT1 interacts with MAPK10ProteinHetionet hetionet:interacts:4661-5602Inferred only

Show the remaining 11

MYT1 interacts with MAPK8ProteinHetionet hetionet:interacts:4661-5599Inferred only
MYT1 interacts with PIN1ProteinHetionet hetionet:interacts:4661-5300Inferred only
MYT1 interacts with PLK1ProteinHetionet hetionet:interacts:4661-5347Inferred only
MYT1 participates in G1 to S cell cycle controlPathwayWikiPathways WP45Inferred only
MYT1 participates in Integrated breast cancer pathwayPathwayWikiPathways WP1984Inferred only
MYT1 participates in MECP2 and associated Rett syndromePathwayWikiPathways WP3584Inferred only
MYT1 participates in NF1 copy number variation syndrome PathwayWikiPathways WP5366Inferred only
MYT1 participates in Oligodendrocyte developmentPathwayWikiPathways WP5574Inferred only
MYT1 participates in Oligodendrocyte specification and differentiation leading to myelin components for CNSPathwayWikiPathways WP4304Inferred only
MYT1 regulates regulation of DNA-templated transcriptionBiological processgene ontology Q01538|GO:0006355Inferred only
MYT1 increases the expression of DNAJB1ProteinHetionet hetionet:regulates:4661-3337Inferred only

Other names

7 names

Resolves to: MYT1

Also called: KIAA0835KIAA1050MTF1Myelin transcription factor IMYTIPLPB1Proteolipid protein-binding protein

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