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Proteins/UNIPROT:P56748
Can associate with other claudins to regulate tight junction structural and functional strand dynamics (By similarity). May coassemble with CLDN4 into tight junction strands containing anion-selective channels that convey paracellular chloride permeability in renal collecting ducts (By similarity). Cannot form tight junction strands on its own..
Function from UniProtKB (P56748), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 1 · transported by
1 compound
1 compound.
0 reported routes1 assembled route
13 statements
13 statements · 5 reference databases · Subject: CLDN8 · Sources: Bgee, Hetionet, Reactome, Rhea, WikiPathways
4 reactions
1 name
Resolves to: CLDN8
Transported by GPHRA or CLIC1 or CLDN4 or SLC26A4 or GPHRB or CLCN1 or SLC1A4 or CLCN2 or CLCNKA or CLCNKB or CLDN8 or CLDN17 and 14 more alternatives
Reaction pageReversibleBalanced
Rhea RHEA:66324CC BY 4.0Reference data
Transported by GPHRA or CLIC1 or CLDN4 or GPHRB or CLCN1 or CLCN2 or CLCNKA or CLCNKB or CLDN8 or CLDN17 or AQP6 or SLC5A8 and 3 more alternatives
Reaction pageDirection not assertedBalanced
Rhea RHEA:75383CC BY 4.0Reference data