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Proteins/UNIPROT:Q9NZN5
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Promotes endothelial cell and actin stress fiber reorientation in response to mechanotransduction (By similarity)..
Function from UniProtKB (Q9NZN5), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
59 statements
59 statements · 4 reference databases · Subject: ARHGEF12 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
4 names
Resolves to: ARHGEF12