Pathway
Developmental Cell Lineages of the Integumentary System
The integumentary system consists of skin, the largest organ of the body that serves as a barrier from the outside world, and its adnexal structures, such as hair, nails, sebaceous, apocrine, and mammary glands (Sundberg et al. "Skin and Adnexa", pp. 511-542).
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Epidermis is the outermost skin layer, facing the outside environment, and consists of stratified squamous epithelial cells called keratinocytes (Sundberg et al. "Skin and Adnexa", pp. 511-542).
Mammary glands are modified apocrine (sweat) glands that secrete milk, the primary food source of newborn mammals (Sundberg et al. "Skin and Adnexa", pp. 511-542).
REACT:R-HSA-9734779Reactome
What the reference databases state
Statements
74 statements
74 statements · 1 reference database · Subject: Developmental Cell Lineages of the Integumentary System · Sources: Reactome
- ABCG2 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- ACTA2 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- ALDH1A1 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- ALDH1A3 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- ANKRD30A participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- AQP3 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- AREG participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- CALML5 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- CASP14 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- CD24 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- CD44 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- CDH1 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
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- CDH3 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- CNN1 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- COL17A1 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- CSN2 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- CSPG4 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- DLL1 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- DLX5 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- DMKN participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- EGF participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- EGFR participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- ELF5 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- EPCAM participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- ERBB2 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- ESR1 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- FABP5 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- FGF10 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- FLG participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- GATA3 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- GJB3 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- HOPX participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- ITGA6 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- ITGB1 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- ITGB4 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- IVL participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- KIT participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- KLK5 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- KLK7 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- KPRP participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- KRT1 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- KRT10 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- KRT14 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- KRT15 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- KRT18 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- KRT19 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- KRT24 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- KRT5 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- KRT78 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- KRT8 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- KRTDAP participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- LALBA participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- LGALS7; LGALS7B participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- LORICRIN participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- LRIG1 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- MFGE8 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- MME participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- MUC1 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- MYH11 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- NUMB participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- PGR participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- PRL participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- PRSS3 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- SBSN participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- SLPI participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- SPINK5 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- SPRR2A participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- TFAP2A participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- TFAP2C participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- TFRC participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- TGFA participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- TP63 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- VIM participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only
- YAP1 participates in Developmental Cell Lineages of the Integumentary SystemProteinReactome R-HSA-9734779Inferred only