Pathway
RNA Polymerase III Transcription Initiation
There are three basic types of RNA polymerase III promoters. The three types of RNA polymerase III promoters are known as type 1, type 2, and type 3 promoters. Type 1 promoters are found in the 5S genes and consist of a gene-internal element called the internal control region (ICR), that is subdivided into A block, intermediate element, and C block. Type 2 promoters are found in tRNA genes, Adenovirus 2 VAI gene, and other genes. These promoters consists of two gene-internal elements called the A and the B boxes. Type 3 promoters consist of a distal sequence element (DSE) that serves as an enhancer, a proximal sequence element (PSE), and a TATA box.
Continue reading
Some promoters combine elements from type 2 and 3 promoters. For example, the S. cerevisiae U6 promoter, also shown in the figure, contains the TATA box typical of type 3 promoters and the A and B boxes typical of type 2 promoters. Moreover, in S. pombe, nearly all tRNA and 5S genes contain a TATA box in addition to gene-internal elements, and the TATA box is required for transcription.
What the reference databases state
Statements
35 statements
35 statements · 1 reference database · Subject: RNA Polymerase III Transcription Initiation · Sources: Reactome
- BDP1 participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- BRF1 participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- BRF2 participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- CRCP participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- GTF3A participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- GTF3C1 participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- GTF3C2 participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- GTF3C3 participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- GTF3C4 participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- GTF3C5 participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- GTF3C6 participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- POLR1C participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
Show the remaining 23
- POLR2E participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- POLR2F participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- POLR2H participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- POLR2K participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- POLR2L participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- POLR3A participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- POLR3B participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- POLR3C participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- POLR3D participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- POLR3E participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- POLR3F participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- POLR3G participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- POLR3GL participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- POLR3H participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- POLR3K participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- POU2F1 participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- SNAPC1 participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- SNAPC2 participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- SNAPC3 participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- SNAPC4 participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- SNAPC5 participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- TBP participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only
- ZNF143 participates in RNA Polymerase III Transcription InitiationProteinReactome R-HSA-76046Inferred only