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Proteins/UNIPROT:P14859
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR..
(Microbial infection) In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes..
Function from UniProtKB (P14859), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
37 statements
37 statements · 4 reference databases · Subject: POU2F1 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
7 names
Resolves to: POU2F1