Pathway
Developmental Lineage of Pancreatic Ductal Cells
Ductal epithelial cells line the pancreatic ducts in a single layer, changing the shape as ducts increase in size from cuboidal, through low columnar, to high columnar epithelium (Liggitt and Dintzis, “Pancreas”, pp. 241-250). Ductal epithelial cells may have cilia or microvilli on their apical surface (Liggitt and Dintzis, “Pancreas”, pp. 241-250). Besides ductal epithelial cells, main pancreatic ducts sometimes include goblet cells (Liggitt and Dintzis, “Pancreas”, pp. 241-250).
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Ductal epithelial cells develop from bipotent pancreatic trunk progenitor cells, which also give rise to endocrine progenitors and are derived from the primary multipotent pancreatic progenitor cells (reviewed in Shih et al. 2013, Jennings et al. 2015).
REACT:R-HSA-9925563Reactome
What the reference databases state
Statements
48 statements
48 statements · 1 reference database · Subject: Developmental Lineage of Pancreatic Ductal Cells · Sources: Reactome
- ANXA1 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- ANXA2 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- ANXA3 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- AQP1 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- CA2 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- CD74 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- CFTR participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- CLDN10 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- COL11A1 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- COL11A2 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- COL1A1 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- COL1A2 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
Show the remaining 36
- COL24A1 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- COL27A1 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- COL2A1 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- COL3A1 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- COL5A1 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- COL5A2 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- COL5A3 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- ERICH5 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- FN1 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- FOXA2 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- GATA4 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- HNF1B participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- KRT17 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- KRT19 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- KRT23 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- KRT7 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- LAMA1 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- LAMA2 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- LAMA3 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- LAMA4 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- LAMA5 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- LAMB1 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- LAMB2 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- LAMB3 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- LAMC1 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- LAMC2 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- LAMC3 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- NKX6-1 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- ONECUT1 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- PDX1 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- PROM1 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- SLC4A4 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- SOX9 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- TFPI2 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- VTN participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only
- YAP1 participates in Developmental Lineage of Pancreatic Ductal CellsProteinReactome R-HSA-9925563Inferred only