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Proteins/UNIPROT:P13647
Structural component of intermediate filaments in basal keratinocytes of stratified epithelia. Forms heteropolymers with type I partners including KRT14 and KRT15, contributing to the formation of the keratin intermediate filament network that provides mechanical stability and resilience to the basal layer of the epidermis. Regulates the recruitment of Langerhans cells to the epidermis, potentially by modulation of the abundance of macrophage chemotactic cytokines, macrophage inflammatory cytokines and CTNND1 localization in keratinocytes (By similarity)..
Function from UniProtKB (P13647), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
10 rows
50 statements
50 statements · 3 reference databases · Subject: KRT5 · Sources: gene ontology, Hetionet, Reactome
6 names
Resolves to: KRT5