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5-methoxy-2-methyl-3-(all-trans-decaprenyl)benzene-1,4-diol

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

9 compounds within 3 steps: 2 in 1, 4 in 2, 3 in 3

Does it reach a compound?

One step

2-methoxy-6-(all-trans-decaprenyl)benzene-1,4-diolReach from here →
1. 2-methoxy-6-(all-trans-decaprenyl)benzene-1,4-diol + S-adenosyl-L-methionine = 5-methoxy-2-methyl-3-(all-trans-decaprenyl)benzene-1,4-diol + S-adenosyl-L-homocysteine + H(+)
Catalysed by COQ5
3-demethylubiquinol-10Reach from here →
1. coenzyme Q7, hydroxylase
Catalysed by COQ7mitochondrial matrix

Two steps

ubiquinolReach from here →
1. coenzyme Q7, hydroxylase
2. coenzyme Q3, methyltransferase (3-demethylubiquinol-10)
Catalysed by COQ7, COQ3mitochondrial matrix
3-demethylubiquinone-10Reach from here →
1. coenzyme Q7, hydroxylase
2. 3-demethylubiquinone-10 + NADH + 2 H(+) = 3-demethylubiquinol-10 + NAD(+)
Catalysed by COQ7, RTN4IP1mitochondrial matrixOne of 2 routes
2-methoxy-6-(all-trans-decaprenyl)phenolReach from here →

Three steps

ubiquinonesReach from here →
Catalysed by COQ7, COQ3, SDHD, SDHB and 2 moremitochondrial matrixOne of 5 routes
ferrocytochrome cReach from here →
Catalysed by and 8 more

2-methoxy-6-(all-trans-decaprenyl)benzene-1,4-diol + S-adenosyl-L-methionine = 5-methoxy-2-methyl-3-(all-trans-decaprenyl)benzene-1,4-diol + S-adenosyl-L-homocysteine + H(+)
2-methoxy-6-(all-trans-decaprenyl)phenol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = 2-methoxy-6-(all-trans-decaprenyl)benzene-1,4-diol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Catalysed by COQ5, COQ6

ubiquinol-10Reach from here →

coenzyme Q7, hydroxylase
3-demethylubiquinol-10 + S-adenosyl-L-methionine = ubiquinol-10 + S-adenosyl-L-homocysteine + H(+)

Catalysed by COQ7, COQ3mitochondrial matrix

mitochondrial matrix, mitochondrial intermembrane space

4-hydroxy-3-methoxy-5-(all-trans-decaprenyl)benzoateReach from here →

2-methoxy-6-(all-trans-decaprenyl)benzene-1,4-diol + S-adenosyl-L-methionine = 5-methoxy-2-methyl-3-(all-trans-decaprenyl)benzene-1,4-diol + S-adenosyl-L-homocysteine + H(+)
2-methoxy-6-(all-trans-decaprenyl)phenol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = 2-methoxy-6-(all-trans-decaprenyl)benzene-1,4-diol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O
4-hydroxy-3-methoxy-5-(all-trans-decaprenyl)benzoate + H(+) = 2-methoxy-6-(all-trans-decaprenyl)phenol + CO2

Catalysed by COQ5, COQ6, COQ4