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Proteins/UNIPROT:P14410
Bifunctional enzyme with both sucrase and isomaltase activities involved in breakdown of dietary starch oligosaccharides in small intestine. The isomaltase domain hydrolazes alpha-1,6-glycosidic linkages in isomaltose. The sucrase domain cleaves the alpha-1,2-glycosidic linkages in sucrose to form glucose and fructose, and contributes to the cleavage of the alpha-1,4-glycosidic linkage in maltose to form two glucose monosaccharides..
Function from UniProtKB (P14410), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 1 · substrate of
1 compound
1 compound.
0 reported routes1 assembled route
1 row
28 statements
28 statements · 6 reference databases · Subject: SI · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea
8 reactions
water+MAM03622eD-glucose+MAM03623e
Catalysed by SI
Reaction pageLeft to rightBalancedEC 3.2.1.10extracellular space
Human-GEM MAR01560CC BY 4.0Reference data
water+sucrosebeta-D-fructose+D-glucose
Catalysed by SI or GANC or MGAM
Reaction pageLeft to rightBalancedEC 3.2.1.10, 3.2.1.20, 3.2.1.48
1 name
Resolves to: SI
Human-GEM MAR04303CC BY 4.0Reference data
water+MAM02937eD-glucose+alpha-D-glucosyl-(1->4)-alpha-D-mannose
Catalysed by SI
Reaction pageLeft to rightBalancedEC 3.2.1.10extracellular space
Human-GEM MAR08584CC BY 4.0Reference data
MAM01678c+waterMAM01677c+D-glucose
Catalysed by SI or KANSL3 or MGAM
Reaction pageLeft to rightBalancedEC 3.2.1.3, 3.2.1.10cytosol
Human-GEM MAR09464CC BY 4.0Reference data
Catalysed by SI
Reaction pageLeft to rightBalancedEC 3.2.1.10extracellular space
Human-GEM MAR09465CC BY 4.0Reference data
sucrose+waterbeta-D-fructose+alpha-D-glucose
Catalysed by SI
Reaction pageDirection not assertedBalanced
Rhea RHEA:33795CC BY 4.0Reference data
maltose+wateralpha-D-glucose+D-glucose
Reaction pageLeft to rightBalanced
Rhea RHEA:68796CC BY 4.0Reference data
isomaltose+wateralpha-D-glucose+D-glucose
Reaction pageLeft to rightBalanced
Rhea RHEA:68864CC BY 4.0Reference data