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Proteins/UNIPROT:Q8N335
Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L..
Function from UniProtKB (Q8N335), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
64 statements
64 statements · 7 reference databases · Subject: GPD1L · Sources: Bgee, gene ontology, Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
3 reactions
CHEBI:16108+proton+NADH(2-)NAD(+)+CHEBI:15978
Reaction pageLeft to rightBalancedEC 1.1.1.8cytosol
Human-GEM MAR00479CC BY 4.0Reference data
CHEBI:16108+proton+NADH(2-)NAD(+)+CHEBI:15978
Catalysed by GPD1L
2 names
Resolves to: GPD1L
Reaction pageLeft to rightBalancedEC 1.1.1.8peroxisome
Human-GEM MAR00481CC BY 4.0Reference data
sn-glycerol 3-phosphate+NAD(1-)dihydroxyacetone phosphate+NADH(2-)+hydron
Reaction pageLeft to rightBalanced
Rhea RHEA:11092CC BY 4.0Reference data