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Proteins/UNIPROT:P21695

GPD1

Protein·UNIPROT:P21695Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

Open in the graph

Has glycerol-3-phosphate dehydrogenase activity..

Function from UniProtKB (P21695), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

1 row

transient infantile hypertriglyceridemia and hepatosteatosis has a germline basis in GPD1DiseaseGenCC HGNC:4455|MONDO:0013771Inferred only

Statements

68 statements

68 statements · 7 reference databases · Subject: GPD1 · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways

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GPD1 covaries with DUSP23ProteinHetionet hetionet:covaries:2819-54935Inferred only
HMGN5 covaries with GPD1ProteinHetionet hetionet:covaries:2819-79366Inferred only
GPD1 is expressed in adipose tissueAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in adipose tissueAnatomyBgee ENSG00000167588Inferred only
GPD1 is expressed in adrenal glandAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in breastAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in bronchusAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in C1 segment of cervical spinal cordAnatomyBgee ENSG00000167588Inferred only
GPD1 is expressed in caudate nucleusAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in cerebellumAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in cerebral cortexAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in colonAnatomyHuman Protein Atlas ENSG00000167588Inferred only

Show the remaining 56

GPD1 is expressed in connective tissueAnatomyBgee ENSG00000167588Inferred only
GPD1 is expressed in duodenumAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in endometriumAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in epididymisAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in esophagusAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in fallopian tubeAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in gallbladderAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in gastrocnemiusAnatomyBgee ENSG00000167588Inferred only
GPD1 is expressed in gluteal muscleAnatomyBgee ENSG00000167588Inferred only
GPD1 is expressed in hindlimb stylopod muscleAnatomyBgee ENSG00000167588Inferred only
GPD1 is expressed in liverAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in lungAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in lymph nodeAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in mouth mucosaAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in muscle organAnatomyBgee ENSG00000167588Inferred only
GPD1 is expressed in myocardiumAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in nasopharynxAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in pancreasAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in parathyroid glandAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in peritoneumAnatomyBgee ENSG00000167588Inferred only
GPD1 is expressed in prostate glandAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in quadriceps femorisAnatomyBgee ENSG00000167588Inferred only
GPD1 is expressed in rectumAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in right lobe of liverAnatomyBgee ENSG00000167588Inferred only
GPD1 is expressed in saliva-secreting glandAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in seminal vesicleAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in Skeletal muscle tissueAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in Skeletal muscle tissueAnatomyBgee ENSG00000167588Inferred only
GPD1 is expressed in skeletal muscle tissue of biceps brachiiAnatomyBgee ENSG00000167588Inferred only
GPD1 is expressed in skeletal muscle tissue of rectus abdominisAnatomyBgee ENSG00000167588Inferred only
GPD1 is expressed in Small intestineAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in stomachAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in subcutaneous adipose tissueAnatomyBgee ENSG00000167588Inferred only
GPD1 is expressed in testisAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in thyroid glandAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in tonsilAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in triceps brachiiAnatomyBgee ENSG00000167588Inferred only
GPD1 is expressed in urinary bladderAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GPD1 is expressed in vastus lateralisAnatomyBgee ENSG00000167588Inferred only
GPD1 is expressed in vermiform appendixAnatomyHuman Protein Atlas ENSG00000167588Inferred only
GK interacts with GPD1ProteinHetionet hetionet:interacts:2710-2819Inferred only
GPD1 interacts with MDH1ProteinHetionet hetionet:interacts:2819-4190Inferred only
GPD1 interacts with POMPProteinHetionet hetionet:interacts:2819-51371Inferred only
GPD1 interacts with PTNProteinHetionet hetionet:interacts:2819-5764Inferred only
GPD1 participates in Glycerol metabolism including linked IMDsPathwayWikiPathways WP5570Inferred only
GPD1 participates in Glycerophospholipid biosynthesisPathwayReactome R-HSA-1483206Inferred only
GPD1 participates in Glycerophospholipid biosynthetic pathwayPathwayWikiPathways WP2533Inferred only
GPD1 participates in HIF1A and PPARG in hypertrophic cardiomyopathyPathwayWikiPathways WP2456Inferred only
GPD1 participates in MetabolismPathwayReactome R-HSA-1430728Inferred only
GPD1 participates in Metabolism of lipidsPathwayReactome R-HSA-556833Inferred only
GPD1 participates in Phospholipid metabolismPathwayReactome R-HSA-1483257Inferred only
GPD1 participates in Synthesis of PAPathwayReactome R-HSA-1483166Inferred only
GPD1 participates in Triacylglyceride synthesisPathwayWikiPathways WP325Inferred only
CHEBI:16108 is a substrate of GPD1CompoundHuman-GEM MAR00479Inferred only
CHEBI:16108 is a substrate of GPD1CompoundHuman-GEM MAR00481Inferred only
sn-glycerol 3-phosphate is a substrate of GPD1CompoundRhea RHEA:11092Inferred only

Reactions

3 reactions

CHEBI:16108+proton+NADH(2-)NAD(+)+CHEBI:15978
Catalysed by GPD1L or GPD1
Reaction pageLeft to rightBalancedEC 1.1.1.8cytosol
Human-GEM MAR00479CC BY 4.0Reference data
CHEBI:16108+proton+NADH(2-)NAD(+)+CHEBI:15978
Catalysed by GPD1L

Other names

3 names

Resolves to: GPD1

Also called: +GPD-CGPDH-C

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or GPD1

Reaction pageLeft to rightBalancedEC 1.1.1.8peroxisome

Human-GEM MAR00481CC BY 4.0Reference data

sn-glycerol 3-phosphate+NAD(1-)dihydroxyacetone phosphate+NADH(2-)+hydron

Catalysed by GPD1 or GPD1L

Reaction pageLeft to rightBalanced

Rhea RHEA:11092CC BY 4.0Reference data