Compound
acetic acid
Acetic acid, the two-carbon monocarboxylic acid. THIS NAME COVERS FOUR DIFFERENT SUBJECTS IN THE LITERATURE AND ONLY ONE OF THEM IS THIS NODE. (1) A REAGENT APPLIED TO TISSUE IS NOT AN EXPOSURE. Most of this corpus is visual inspection with acetic acid (VIA) for cervical screening, or chromoendoscopy: the acid is swabbed on to turn abnormal epithelium white and the endpoint is how accurately an observer then reads it. Nothing is being tested about what acetic acid does to a person, so there is no claim here at all. Percutaneous acetic acid injection for hepatocellular carcinoma IS an exposure, but a locally ablative one whose mechanism is chemical destruction at the needle tip; do not pool it with ingestion. (2) VINEGAR IS NOT ACETIC ACID. Most supplement trials dose vinegar or apple cider vinegar, a food material carrying roughly 5-6% acetic acid alongside polyphenols, organic acids and, unfiltered, the mother. A vinegar arm against a comparator lacking it is a combination exposure: the intervention contains more than the compound and no analysis separates them. Record what was given in co_exposure. A defined acetic acid SOLUTION at a stated concentration IS this node, and the concentration belongs in dose_regimen. (3) ACETATE MEASURED IS NOT ACETIC ACID GIVEN. In microbiome and metabolism papers acetate is a short-chain fatty acid produced by gut bacteria and measured in blood, stool or breath. Where the exposure is a fibre, a diet or a bacterial strain and acetate is the readout, the claim runs backwards through the graph: subject_is_the_outcome. (4) THE SALTS AND THE LONGER ACIDS ARE NOT THIS NODE. Potassium acetate is CHEBI:32029. Trichloroacetic acid and diethylenetriamine PENTA-acetic acid are different compounds whose names contain this one; the latter is an MRI contrast agent and three such papers sit in this corpus on a substring match alone.
Structure
- Class
- Organic compound
- Formula
- C2H4O2
- Mass
- 60.052 g/mol
- Charge
- 0
- InChIKey
- QTBSBXVTEAMEQO-UHFFFAOYSA-N
- SMILES
- CC(=O)O
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence — none of it carries a grade.
What it touches on the way
A finding says acetic acid moved an endpoint. This is the biology in between: the proteins and reactions it runs through to get there. It is where to look for the two things a list of findings cannot answer — why a result might happen, and what else acts on the same machinery.
40 of these are proteins with a page of their own, and that is the door: a protein page says what else it carries, which is how one compound leads to the next.
Mechanistic reach
40 entities
40 entities reached, most connected first. Hub metabolites are excluded, so this is not a claim that the compound touches everything.
0 reported hop40 assembled from the scaffold
- HDAC1ProteinUNIPROT:Q13547substrate ofInferred only230 paths115 endpoints
- HDAC2ProteinUNIPROT:Q92769substrate ofInferred only158 paths79 endpoints
- HDAC3ProteinUNIPROT:O15379substrate ofInferred only152 paths76 endpoints
- HDAC10ProteinUNIPROT:Q969S8substrate ofInferred only84 paths21 endpoints
- HDAC6ProteinUNIPROT:Q9UBN7substrate ofInferred only70 paths35 endpoints
- HDAC7ProteinUNIPROT:Q8WUI4substrate ofInferred only54 paths27 endpoints
- HDAC8ProteinUNIPROT:Q9BY41substrate ofInferred only42 paths21 endpoints
- PAFAH1B2ProteinUNIPROT:P68402substrate ofInferred only32 paths8 endpoints
- CYP17A1ProteinUNIPROT:P05093metabolized byInferred only30 paths10 endpoints
- HDAC4ProteinUNIPROT:P56524substrate ofInferred only29 paths29 endpoints
- HDAC5ProteinUNIPROT:Q9UQL6substrate ofInferred only22 paths22 endpoints
- PLA2G7ProteinUNIPROT:Q13093substrate ofInferred only21 paths3 endpoints
Show the remaining 28
- HDAC11ProteinUNIPROT:Q96DB2substrate ofInferred only18 paths18 endpoints
- ALDH1A1ProteinUNIPROT:P00352metabolized byInferred only18 paths18 endpoints
- HDAC9ProteinUNIPROT:Q9UKV0substrate ofInferred only18 paths18 endpoints
- ACY1ProteinUNIPROT:Q03154substrate ofInferred only18 paths9 endpoints
- PLA2G6ProteinUNIPROT:O60733substrate ofInferred only16 paths16 endpoints
- PAFAH1B3ProteinUNIPROT:Q15102substrate ofInferred only15 paths5 endpoints
- ACOT8ProteinUNIPROT:O14734substrate ofInferred only14 paths14 endpoints
- CES1ProteinUNIPROT:P23141metabolized byInferred only11 paths11 endpoints
- ASAH1ProteinUNIPROT:Q13510substrate ofInferred only11 paths11 endpoints
- ACHEProteinUNIPROT:P22303substrate ofInferred only11 paths11 endpoints
- ABHD3ProteinUNIPROT:Q8WU67substrate ofInferred only10 paths5 endpoints
- LIPEProteinUNIPROT:Q05469substrate ofInferred only10 paths10 endpoints
- PLA2G10ProteinUNIPROT:O15496substrate ofInferred only10 paths10 endpoints
- ACSS3ProteinUNIPROT:Q9H6R3substrate ofInferred only10 paths10 endpoints
- NCEH1ProteinUNIPROT:Q6PIU2substrate ofInferred only8 paths4 endpoints
- ACSS2ProteinUNIPROT:Q9NR19substrate ofInferred only7 paths7 endpoints
- PON3ProteinUNIPROT:Q15166substrate ofInferred only7 paths7 endpoints
- PON1ProteinUNIPROT:P27169substrate ofInferred only7 paths7 endpoints
- CELProteinUNIPROT:P19835substrate ofInferred only7 paths7 endpoints
- AMDHD2ProteinUNIPROT:Q9Y303substrate ofInferred only6 paths6 endpoints
- ALDH1B1ProteinUNIPROT:P30837metabolized byInferred only6 paths6 endpoints
- NDST1ProteinUNIPROT:P52848substrate ofInferred only5 paths5 endpoints
- PON2ProteinUNIPROT:Q15165substrate ofInferred only5 paths5 endpoints
- CES2ProteinUNIPROT:O00748metabolized byInferred only5 paths5 endpoints
- ADPRSProteinUNIPROT:Q9NX46substrate ofInferred only5 paths5 endpoints
- PIGLProteinUNIPROT:Q9Y2B2substrate ofInferred only4 paths4 endpoints
- ACOT12ProteinUNIPROT:Q8WYK0substrate ofInferred only4 paths4 endpoints
- PAFAH2ProteinUNIPROT:Q99487substrate ofInferred only4 paths2 endpoints
Where it reaches
1 system, 1 region, 1 tissue, 1 transporter route.
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