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Proteins/UNIPROT:Q8NBI5
Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobases such as adenine, guanine and hypoxanthine. May regulate fatty acid (FA) transport in adipocytes, acting as a positive regulator of FA efflux and as a negative regulator of FA uptake (By similarity)..
[Isoform 1]: Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine. Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane..
[Isoform 2]: Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine. Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane..
Function from UniProtKB (Q8NBI5), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
19 statements
19 statements · 3 reference databases · Subject: SLC43A3 · Sources: Bgee, Hetionet, Rhea
3 reactions
Transported by SLC29A2 or SLC43A3 or SLC29A1
Reaction pageReversibleBalanced
Rhea RHEA:71515CC BY 4.0Reference data
Transported by AQP9 or SLC29A2 or SLC43A3 or SLC29A1
Reaction pageReversibleBalanced
Rhea RHEA:71523CC BY 4.0Reference data
4 names
Resolves to: SLC43A3
Transported by SLC29A2 or SLC43A3 or SLC29A1 or SLC29A3
Reaction pageReversibleBalanced
Rhea RHEA:71531CC BY 4.0Reference data