Compound

a ganglioside GD1b

An anionic ganglioside arising from deprotonation of the neuraminosyl carboxy groups of β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl-(1→4)-[α-N-acetylneuraminosyl-(2→8)-α-N-acetylneuraminosyl-(2→3)]-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1')-ceramide; major species at pH 7.3.

Definition from ChEBI (CHEBI:82939), read 2026-09-23. CC BY 4.0.

CHEBI:82939ChEBI

Open in the graph

Structure

2D depiction

Class: Structural class, not a single molecule
Formula: C52H82N4O39R2
Mass: 1387.213 g/mol
Charge: -2
SMILES: *C(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@H](O)[C@H](O)[C@H]4O)[C@H]3NC(C)=O)[C@H](O[C@]3(C(=O)[O-])C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@@H](CO)O[C@]4(C(=O)[O-])C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@H](O)CO)O4)O3)[C@H]2O)[C@H](O)[C@H]1O)[C@@H](*)O
Look it up: ChEBI

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

5 entities

5 entities reached.

0 reported hops5 assembled from the scaffold

What the reference databases state

Statements

5 statements

5 statements · 1 reference database · Subject: a ganglioside GD1b · Sources: Rhea

Order

a ganglioside GD1b is a substrate of FUT2ProteinRhea RHEA:48324Inferred only
a ganglioside GD1b is a substrate of NEU2ProteinRhea RHEA:47876Inferred only
a ganglioside GD1b is a substrate of NEU3ProteinRhea RHEA:47876Inferred only
a ganglioside GD1b is a substrate of ST3GAL1ProteinRhea RHEA:48240Inferred only
a ganglioside GD1b is a substrate of ST3GAL2ProteinRhea RHEA:48240Inferred only

Reactions

8 reactions

a ganglioside GT1b+watera ganglioside GD1b+N-acetylneuraminate
Catalysed by NEU3 or NEU2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47828CC BY 4.0Reference data
a ganglioside GD1b+watera ganglioside GM1+N-acetylneuraminate
Catalysed by NEU3 or NEU2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47876CC BY 4.0Reference data
a ganglioside GD1b+CMP-N-acetyl-beta-neuraminatea ganglioside GT1b+CMP+hydron
Catalysed by ST3GAL1 or ST3GAL2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:48240CC BY 4.0Reference data
a ganglioside GD2+UDP-alpha-D-galactosea ganglioside GD1b+UDP+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:48252CC BY 4.0Reference data
a ganglioside GD1b+GDP-beta-L-fucosea ganglioside Fuc-GD1b+GDP+hydron
Catalysed by FUT2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:48324CC BY 4.0Reference data
a ganglioside GD1b+CMP-N-acetyl-beta-neuraminateCHEBI:142069+CMP+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:57656CC BY 4.0Reference data
a ganglioside GD1b+UDP-alpha-D-galactoseCHEBI:141776+UDP+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:79739CC BY 4.0Reference data
a ganglioside GD1b+acetyl-CoACHEBI:230548+coenzyme A(4-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:79811CC BY 4.0Reference data

Other names

5 names

Resolves to: a ganglioside GD1b

Also called: beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(11')-Cer(2-)Ganglioside GD1bganglioside GD1b(2-)ganglioside GD1b(2−)β-D-Gal-(1→3)-β-D-GalNAc-(1→4)-[α-Neu5Ac-(2→8)-α-Neu5Ac-(2→3)]-β-D-Gal-(1→4)-β-D-Glc-(1↔1')-Cer(2−)