Compound

16alpha,17alpha-dihydroxypregnenolone

A pregnane sterol that is pregnenolone substituted by two hydroxy groups at positions 16 and 17 (16α,17α-stereoisomer).

Definition from ChEBI (CHEBI:137049), read 2026-09-23. CC BY 4.0.

CHEBI:137049ChEBI

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Structure

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A generated conformer of 16alpha,17alpha-dihydroxypregnenolone — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound
Formula: C21H32O4
Mass: 348.483 g/mol
Charge: 0
InChIKey: JUTWIBFBXPFWGP-XXHSLLPRSA-N
SMILES: [H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@@]1(C)[C@@]2([H])C[C@@H](O)[C@]1(O)C(C)=O
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

1 entity

1 entities reached.

0 reported hops1 assembled from the scaffold

CYP17A1ProteinUNIPROT:P05093metabolized byInferred only28 paths28 endpoints

What the reference databases state

Statements

1 statement

1 statement · 1 reference database · Subject: 16alpha,17alpha-dihydroxypregnenolone · Sources: Rhea

Order

16alpha,17alpha-dihydroxypregnenolone is metabolised by CYP17A1ProteinRhea RHEA:53224Inferred only

Reactions

1 reaction

16alpha,17alpha-dihydroxypregnenolone+reduced [NADPH--hemoprotein reductase]+dioxygen3beta,16alpha-dihydroxy-androst-5-en-17-one+acetate+oxidized [NADPH--hemoprotein reductase]+water+2hydron
Catalysed by CYP17A1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:53224CC BY 4.0Reference data

Other names

6 names

Resolves to: 16alpha,17alpha-dihydroxypregnenolone

Also called: (beta,16alpha)-3,16,17-trihydroxypregn-5-en-20-one(β,16α)-3,16,17-trihydroxypregn-5-en-20-one16alpha,17-dihydroxypregnenolone16α,17-dihydroxypregnenolone
Systematic name: 3beta,16alpha-trihydroxypregn-5-en-20-one3β,16α-trihydroxypregn-5-en-20-one