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Proteins/UNIPROT:Q8TD26
ATP-dependent chromatin-remodeling factor. Regulates transcription by disrupting nucleosomes in a largely non-sliding manner which strongly increases the accessibility of chromatin; nucleosome disruption requires ATP. Activates transcription of specific genes in response to oxidative stress through interaction with NFE2L2..
(Microbial infection) Acts as a transcriptional repressor of different viruses including influenza virus or papillomavirus. During influenza virus infection, the viral polymerase complex localizes CHD6 to inactive chromatin where it gets degraded in a proteasome independent-manner..
Function from UniProtKB (Q8TD26), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
17 statements
17 statements · 3 reference databases · Subject: CHD6 · Sources: gene ontology, Hetionet, Reactome
1 reaction
6 names
Resolves to: CHD6
Rhea RHEA:13065CC BY 4.0Reference data