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Proteins/UNIPROT:Q9NQW5
Histone methyltransferase that selectively methylates 'Lys-4' of dimethylated histone H3 (H3K4me2) to produce trimethylated 'Lys-4' histone H3 (H3K4me3). May play a role in epigenetic regulation of gene expression by defining an active chromatin state..
Function from UniProtKB (Q9NQW5), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
46 statements
46 statements · 3 reference databases · Subject: PRDM7 · Sources: gene ontology, Hetionet, Reactome
1 reaction
N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3]+S-adenosyl-L-methionineN(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3]+S-adenosyl-L-homocysteine+hydron
Catalysed by SETD1A or PRDM7 or SETD1B
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:60272CC BY 4.0Reference data
4 names
Resolves to: PRDM7