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Proteins/UNIPROT:P31153
Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate..
Function from UniProtKB (P31153), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
297 statements
297 statements · 8 reference databases · Subject: MAT2A · Sources: Bgee, gene ontology, Hetionet, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
3 reactions
ATP+water+L-methioninephosphate(3-)+diphosphate(3-)+S-adenosyl-L-methionine
Catalysed by MAT2B or MAT1A or MAT2A
Reaction pageLeft to rightBalancedEC 2.5.1.6cytosol
Human-GEM MAR03875CC BY 4.0Reference data
7 names
Resolves to: MAT2A
Reaction pageReversibleBalancedEC 2.5.1.6cytosol
Human-GEM MAR07139CC BY 4.0Reference data
L-methionine+ATP(4-)+waterS-adenosyl-L-methionine+hydrogenphosphate+diphosphate(3-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:21080CC BY 4.0Reference data