KCNK17

K(+) channel that conducts voltage-dependent outward rectifying currents upon membrane depolarization. Voltage sensing is coupled to K(+) electrochemical gradient in an 'ion flux gating' mode where outward but not inward ion flow opens the gate. Homo- and heterodimerizes to form functional channels with distinct regulatory and gating properties. Present in the cardiac conduction system where it may regulate action potential duration and beating frequency of cardiac myocytes. Permeable to other monovalent cations such as Rb(+) and Cs(+) (By similarity)..

Function from UniProtKB (Q96T54), read 2026-09-23. CC BY 4.0.