Proteins/UNIPROT:Q9P0U4

CXXC1

ProteinUNIPROT:Q9P0U4

Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG..

Function from UniProtKB (Q9P0U4), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

109 statements

109 statements · 4 reference databases · Subject: CXXC1 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

CXXC1 covaries with ADGRB2ProteinHetionet hetionet:covaries:30827-576Inferred only
AHDC1 covaries with CXXC1ProteinHetionet hetionet:covaries:27245-30827Inferred only
AMOTL2 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-51421Inferred only
CXXC1 covaries with ANO3ProteinHetionet hetionet:covaries:30827-63982Inferred only
CXXC1 covaries with ARRB1ProteinHetionet hetionet:covaries:30827-408Inferred only
ASCC1 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-51008Inferred only
ATP1B4 covaries with CXXC1ProteinHetionet hetionet:covaries:23439-30827Inferred only
CXXC1 covaries with ATP6V0BProteinHetionet hetionet:covaries:30827-533Inferred only
B3GALT1 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-8708Inferred only
CXXC1 covaries with B4GAT1ProteinHetionet hetionet:covaries:11041-30827Inferred only
CA8 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-767Inferred only
CACNB3 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-784Inferred only

Show the remaining 97

CADM4 covaries with CXXC1ProteinHetionet hetionet:covaries:199731-30827Inferred only
CAPN6 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-827Inferred only
CCDC120 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-90060Inferred only
CLTA covaries with CXXC1ProteinHetionet hetionet:covaries:1211-30827Inferred only
CXXC1 covaries with CMASProteinHetionet hetionet:covaries:30827-55907Inferred only
CREB3L2 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-64764Inferred only
CXXC1 covaries with CSTF3ProteinHetionet hetionet:covaries:1479-30827Inferred only
CXXC1 covaries with DERL2ProteinHetionet hetionet:covaries:30827-51009Inferred only
CXXC1 covaries with DHX40ProteinHetionet hetionet:covaries:30827-79665Inferred only
DZIP3 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-9666Inferred only
EIF1AX covaries with CXXC1ProteinHetionet hetionet:covaries:1964-30827Inferred only
EPM2AIP1 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-9852Inferred only
ERP44 covaries with CXXC1ProteinHetionet hetionet:covaries:23071-30827Inferred only
FAXC covaries with CXXC1ProteinHetionet hetionet:covaries:30827-84553Inferred only
FBXO10 covaries with CXXC1ProteinHetionet hetionet:covaries:26267-30827Inferred only
FEZF2 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-55079Inferred only
GABRA3 covaries with CXXC1ProteinHetionet hetionet:covaries:2556-30827Inferred only
CXXC1 covaries with GCN1ProteinHetionet hetionet:covaries:10985-30827Inferred only
GET3 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-439Inferred only
CXXC1 covaries with GNAI3ProteinHetionet hetionet:covaries:2773-30827Inferred only
CXXC1 covaries with GRB2ProteinHetionet hetionet:covaries:2885-30827Inferred only
CXXC1 covaries with HES7ProteinHetionet hetionet:covaries:30827-84667Inferred only
HHATL covaries with CXXC1ProteinHetionet hetionet:covaries:30827-57467Inferred only
HOXA5 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-3202Inferred only
HYAL2 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-8692Inferred only
IGIP covaries with CXXC1ProteinHetionet hetionet:covaries:30827-492311Inferred only
CXXC1 covaries with IKZF4ProteinHetionet hetionet:covaries:30827-64375Inferred only
KDM5C covaries with CXXC1ProteinHetionet hetionet:covaries:30827-8242Inferred only
KLHL9 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-55958Inferred only
LENG8 covaries with CXXC1ProteinHetionet hetionet:covaries:114823-30827Inferred only
LMO2 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-4005Inferred only
LOXHD1 covaries with CXXC1ProteinHetionet hetionet:covaries:125336-30827Inferred only
LSM5 covaries with CXXC1ProteinHetionet hetionet:covaries:23658-30827Inferred only
NCOA5 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-57727Inferred only
CXXC1 covaries with NR0B2ProteinHetionet hetionet:covaries:30827-8431Inferred only
OTUD4 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-54726Inferred only
CXXC1 covaries with PARD6AProteinHetionet hetionet:covaries:30827-50855Inferred only
PCDHB1 covaries with CXXC1ProteinHetionet hetionet:covaries:29930-30827Inferred only
PGAP4 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-84302Inferred only
PKIA covaries with CXXC1ProteinHetionet hetionet:covaries:30827-5569Inferred only
PLXNA1 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-5361Inferred only
PPP3R1 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-5534Inferred only
PREPL covaries with CXXC1ProteinHetionet hetionet:covaries:30827-9581Inferred only
PRMT1 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-3276Inferred only
RAC1 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-5879Inferred only
RHOA covaries with CXXC1ProteinHetionet hetionet:covaries:30827-387Inferred only
CXXC1 covaries with RHOGProteinHetionet hetionet:covaries:30827-391Inferred only
RIMOC1 covaries with CXXC1ProteinHetionet hetionet:covaries:285636-30827Inferred only
RNF112 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-7732Inferred only
RNF182 covaries with CXXC1ProteinHetionet hetionet:covaries:221687-30827Inferred only
RNF215 covaries with CXXC1ProteinHetionet hetionet:covaries:200312-30827Inferred only
SKP2 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-6502Inferred only
SLC35E4 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-339665Inferred only
SMC6 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-79677Inferred only
SPECC1L covaries with CXXC1ProteinHetionet hetionet:covaries:23384-30827Inferred only
CXXC1 covaries with SRSF5ProteinHetionet hetionet:covaries:30827-6430Inferred only
STXBP1 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-6812Inferred only
TAGLN3 covaries with CXXC1ProteinHetionet hetionet:covaries:29114-30827Inferred only
CXXC1 covaries with TCF25ProteinHetionet hetionet:covaries:22980-30827Inferred only
TFE3 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-7030Inferred only
TMC1 covaries with CXXC1ProteinHetionet hetionet:covaries:117531-30827Inferred only
TNKS covaries with CXXC1ProteinHetionet hetionet:covaries:30827-8658Inferred only
CXXC1 covaries with TRMT61AProteinHetionet hetionet:covaries:115708-30827Inferred only
UBL5 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-59286Inferred only
UBP1 covaries with CXXC1ProteinHetionet hetionet:covaries:30827-7342Inferred only
UHRF2 covaries with CXXC1ProteinHetionet hetionet:covaries:115426-30827Inferred only
ZC3H7B covaries with CXXC1ProteinHetionet hetionet:covaries:23264-30827Inferred only
CXXC1 covaries with ZNF24ProteinHetionet hetionet:covaries:30827-7572Inferred only
CXXC1 covaries with ZNF689ProteinHetionet hetionet:covaries:115509-30827Inferred only
DNMT1 interacts with CXXC1ProteinHetionet hetionet:interacts:1786-30827Inferred only
HSP90AA1 interacts with CXXC1ProteinHetionet hetionet:interacts:30827-3320Inferred only
HSP90AB1 interacts with CXXC1ProteinHetionet hetionet:interacts:30827-3326Inferred only
KMT2D interacts with CXXC1ProteinHetionet hetionet:interacts:30827-8085Inferred only
NR5A1 interacts with CXXC1ProteinHetionet hetionet:interacts:2516-30827Inferred only
PPP1CA interacts with CXXC1ProteinHetionet hetionet:interacts:30827-5499Inferred only
SETD1A interacts with CXXC1ProteinHetionet hetionet:interacts:30827-9739Inferred only
CXXC1 interacts with SMURF1ProteinHetionet hetionet:interacts:30827-57154Inferred only
SUMO2 interacts with CXXC1ProteinHetionet hetionet:interacts:30827-6613Inferred only
TBP interacts with CXXC1ProteinHetionet hetionet:interacts:30827-6908Inferred only
CXXC1 participates in Cellular responses to stimuliPathwayReactome R-HSA-8953897Inferred only
CXXC1 participates in Cellular responses to stressPathwayReactome R-HSA-2262752Inferred only
CXXC1 participates in Epigenetic regulation by WDR5-containing histone modifying complexesPathwayReactome R-HSA-9917777Inferred only
CXXC1 participates in Epigenetic regulation of gene expressionPathwayReactome R-HSA-212165Inferred only
CXXC1 participates in Formation of WDR5-containing histone-modifying complexesPathwayReactome R-HSA-9772755Inferred only
CXXC1 participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
CXXC1 participates in IRE1alpha activates chaperonesPathwayReactome R-HSA-381070Inferred only
CXXC1 participates in Male infertilityPathwayWikiPathways WP4673Inferred only
CXXC1 participates in Unfolded Protein Response (UPR)PathwayReactome R-HSA-381119Inferred only
CXXC1 participates in XBP1(S) activates chaperone genesPathwayReactome R-HSA-381038Inferred only
CXXC1 regulates positive regulation of DNA-templated transcriptionBiological processgene ontology Q9P0U4|GO:0045893Inferred only
CXXC1 regulates regulation of DNA-templated transcriptionBiological processgene ontology Q9P0U4|GO:0006355Inferred only
BCKDHA decreases the expression of CXXC1ProteinHetionet hetionet:regulates:593-30827Inferred only
CD320 decreases the expression of CXXC1ProteinHetionet hetionet:regulates:51293-30827Inferred only
JAZF1 increases the expression of CXXC1ProteinHetionet hetionet:regulates:221895-30827Inferred only
PDHX increases the expression of CXXC1ProteinHetionet hetionet:regulates:8050-30827Inferred only
RAB11A increases the expression of CXXC1ProteinHetionet hetionet:regulates:8766-30827Inferred only
SRC increases the expression of CXXC1ProteinHetionet hetionet:regulates:6714-30827Inferred only

Other names

6 names

Resolves to: CXXC1

Also called: CFP1CGBPCpG-binding proteinPCCX1PHD finger and CXXC domain-containing protein 1PHF18

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