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Proteins/UNIPROT:Q96FX7
Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Catalytic subunit of mRNA N(1)-methyltransferase complex, which mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries..
Function from UniProtKB (Q96FX7), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
34 statements
34 statements · 2 reference databases · Subject: TRMT61A · Sources: Hetionet, Reactome
2 reactions
CHEBI:74411+S-adenosyl-L-methionineCHEBI:74491+S-adenosyl-L-homocysteine+hydron
Catalysed by TRMT61A or TRMT61B
Reaction pageDirection not assertedBalanced
Rhea RHEA:43152CC BY 4.0Reference data
an adenosine in mRNA+S-adenosyl-L-methioninean N(1)-methyladenosine in mRNA+S-adenosyl-L-homocysteine+hydron
Catalysed by TRMT10C or
6 names
Resolves to: TRMT61A
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:55392CC BY 4.0Reference data