Proteins/UNIPROT:Q9BS26

ERP44

ProteinUNIPROT:Q9BS26

Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum..

Function from UniProtKB (Q9BS26), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

13 statements

13 statements · 2 reference databases · Subject: ERP44 · Sources: Hetionet, Reactome

Order

ERP44 covaries with CXXC1ProteinHetionet hetionet:covaries:23071-30827Inferred only
ERP44 covaries with LRFN4ProteinHetionet hetionet:covaries:23071-78999Inferred only
ERP44 covaries with ZNF354BProteinHetionet hetionet:covaries:117608-23071Inferred only
ERP44 interacts with ERO1AProteinHetionet hetionet:interacts:23071-30001Inferred only
ERP44 interacts with ERO1BProteinHetionet hetionet:interacts:23071-56605Inferred only
ITPR1 interacts with ERP44ProteinHetionet hetionet:interacts:23071-3708Inferred only
LMAN1 interacts with ERP44ProteinHetionet hetionet:interacts:23071-3998Inferred only
UBC interacts with ERP44ProteinHetionet hetionet:interacts:23071-7316Inferred only
ERP44 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
ERP44 participates in Innate Immune SystemPathwayReactome R-HSA-168249Inferred only
ERP44 participates in Neutrophil degranulationPathwayReactome R-HSA-6798695Inferred only
C1QA increases the expression of ERP44ProteinHetionet hetionet:regulates:712-23071Inferred only

Show the remaining 1

HSPA5 increases the expression of ERP44ProteinHetionet hetionet:regulates:3309-23071Inferred only

Other names

4 names

Resolves to: ERP44

Also called: ER protein 44KIAA0573Thioredoxin domain-containing protein 4TXNDC4

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