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Proteins/UNIPROT:Q8N6D2
E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway. Also plays a role in the inhibition of TLR-triggered innate immune response by mediating 'Lys'-48-linked ubiquitination and subsequent degradation of NF-kappa-B component RELA..
Function from UniProtKB (Q8N6D2), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
29 statements
29 statements · 2 reference databases · Subject: RNF182 · Sources: Hetionet, Reactome
1 reaction
2 names
Resolves to: RNF182
Reaction pageLeft to rightBalance undeterminableEC 2.3.2.23, 2.3.2.27, 6.2.1.45cytosol
Human-GEM MAR09491CC BY 4.0Reference data