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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Proteins/UNIPROT:Q16134

ETFDH

Protein·UNIPROT:Q16134

Open in the graph

Links fatty acid beta-oxidation and amino acid catabolism to the respiratory chain by transferring electrons from the electron transfer flavoprotein (ETF) to ubiquinone..

Function from UniProtKB (Q16134), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

1 row

multiple acyl-CoA dehydrogenase deficiency has a germline basis in ETFDHDiseaseGenCC HGNC:3483|MONDO:0009282Inferred only

Statements

3 statements

3 statements · 2 reference databases · Subject: ETFDH · Sources: Hetionet, Human-GEM

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ETFDH interacts with UBCProteinHetionet hetionet:interacts:2110-7316Inferred only
ubiquinol is a substrate of ETFDHCompoundHuman-GEM MAR06911Inferred only
ubiquinones is a substrate of ETFDHCompoundHuman-GEM MAR06911Inferred only

Reactions

2 reactions

FADH2+ubiquinonesFAD+ubiquinol
Catalysed by CHDH or PRODH or DHODH or ETFB or GPD2 or SQOR or ETFA or ETFDH or PRODH2
Reaction pageReversibleBalancedEC 1.5.5.1GO:0005759
Human-GEM MAR06911CC BY 4.0Reference data
a ubiquinone

Other names

4 names

Resolves to: ETFDH

Also called: Electron-transferring-flavoprotein dehydrogenaseETF dehydrogenaseETF-QOETF-ubiquinone oxidoreductase

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+

reduced [electron-transfer flavoprotein]

→

a ubiquinol

+oxidized [electron-transfer flavoprotein]

Catalysed by ETFDH

Reaction pageLeft to rightBalance undeterminable

Rhea RHEA:24052CC BY 4.0Reference data