Pathway
Inactivation, recovery and regulation of the phototransduction cascade
To terminate the single photon response and restore the system to its basal state, the three activated intermediates in phototransduction, rhodopsin (MII), transducin alpha subunit with GTP bound (GNAT1-GTP) and phosphodiesterase 6 (PDE6) all need to be efficiently deactivated. In addition, the cGMP concentrations must be restored to support reopening of the CNG channels. This section describes the inactivation and recovery events of the activated intermediates involved in phototransduction.
REACT:R-HSA-2514859Reactome
What the reference databases state
Statements
30 statements
30 statements · 1 reference database · Subject: Inactivation, recovery and regulation of the phototransduction cascade · Sources: Reactome
- CALM1 participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- CAMKMT participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- CNGA1 participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- CNGB1 participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- FNTA participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- FNTB participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- GNAT1 participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- GNB1 participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- GNGT1 participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- GRK1 participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- GRK7 participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- GUCA1A participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
Show the remaining 18
- GUCA1B participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- GUCA1C participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- GUCY2D participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- GUCY2F participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- METAP1 participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- METAP2 participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- NMT1 participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- NMT2 participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- PDE6A participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- PDE6B participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- PDE6G participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- PPEF1 participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- PRKCA participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- PRKCQ participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- RCVRN participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- RGS9BP participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- RHO participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only
- SAG participates in Inactivation, recovery and regulation of the phototransduction cascadeProteinReactome R-HSA-2514859Inferred only