Proteins/UNIPROT:O95843

GUCA1C

ProteinUNIPROT:O95843

Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.

Function from UniProtKB (O95843), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

12 statements

12 statements · 3 reference databases · Subject: GUCA1C · Sources: gene ontology, Hetionet, Reactome

Order

GUCA1C covaries with AP3D1ProteinHetionet hetionet:covaries:8943-9626Inferred only
CASP6 covaries with GUCA1CProteinHetionet hetionet:covaries:839-9626Inferred only
GUCA1C covaries with CEACAM1ProteinHetionet hetionet:covaries:634-9626Inferred only
CLDN20 covaries with GUCA1CProteinHetionet hetionet:covaries:49861-9626Inferred only
GUCA1C covaries with EXT2ProteinHetionet hetionet:covaries:2132-9626Inferred only
GUCA1C covaries with MLST8ProteinHetionet hetionet:covaries:64223-9626Inferred only
TGS1 covaries with GUCA1CProteinHetionet hetionet:covaries:9626-96764Inferred only
GUCA1C participates in Inactivation, recovery and regulation of the phototransduction cascadePathwayReactome R-HSA-2514859Inferred only
GUCA1C participates in Sensory PerceptionPathwayReactome R-HSA-9709957Inferred only
GUCA1C participates in The phototransduction cascadePathwayReactome R-HSA-2514856Inferred only
GUCA1C participates in Visual phototransductionPathwayReactome R-HSA-2187338Inferred only
GUCA1C regulates regulation of signal transductionBiological processgene ontology O95843|GO:0009966Inferred only

Other names

3 names

Resolves to: GUCA1C

Also called: GCAP 3GCAP3Guanylate cyclase activator 1C

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