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Proteins/UNIPROT:O60551
Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Also able to mediate N-terminal lysine myristoylation of proteins: catalyzes myristoylation of ARF6 on both 'Gly-2' and 'Lys-3'. Lysine myristoylation is required to maintain ARF6 on membranes during the GTPase cycle..
Function from UniProtKB (O60551), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
44 statements
44 statements · 5 reference databases · Subject: NMT2 · Sources: gene ontology, Hetionet, Human-GEM, Reactome, Rhea
3 reactions
CHEBI:1146900+MAM02627cMAM02005c+tetradecanoyl-CoA
Reaction pageReversibleBalance undeterminableEC 2.3.1.97cytosol
Human-GEM MAR09512CC BY 4.0Reference data
N-terminal glycyl-[protein]+tetradecanoyl-CoAN-tetradecanoylglycyl-[protein]+coenzyme A(4-)+hydron
5 names
Resolves to: NMT2
Rhea RHEA:15521CC BY 4.0Reference data
N-terminal glycyl-L-lysyl-[protein]+tetradecanoyl-CoAN-terminal glycyl-(N(6)-tetradecanoyl)-L-lysyl-[protein]+coenzyme A(4-)+hydron
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:70671CC BY 4.0Reference data