Endpoint
Time-trial completion time
CAT:outcome/time-trial-performancereported in s
Method
Time to complete a self-paced fixed-DISTANCE trial. Distance and modality recorded on the edge.
The method is part of the endpoint identity. Studies measuring the same quantity by a different method are held as separate endpoints.
Notes
Minted from a single paper, breaking the two-paper rule above, and the exception is deliberate. THIS IS THE MOST DANGEROUS NEAR-MISS IN THE VOCABULARY. Both this and time-to-exhaustion are times in seconds. A time trial fixes the DISTANCE and lets the athlete self-pace, so a FASTER time is better and the number goes DOWN when the compound works. Time to exhaustion fixes the WORKLOAD and measures how long the athlete lasts, so the number goes UP. Mapping a time-trial result onto time-to-exhaustion therefore INVERTS THE SIGN OF THE EFFECT — and the object-plausibility scorer cannot catch it, because "time trial" and "time to exhaustion" share almost all their vocabulary. Leaving this endpoint unminted would not stop extractors meeting it; it would only leave them nowhere correct to put it. A direction on this node describes the TIME, not the performance. Faster is `decreases`.
Findings
2 findings from 2 compounds, strongest first.
caffeine — decreases
LikelyGrade B, Likely. Human evidence, limited replication or design limits.Finding“Both low and moderate caffeine doses significantly reduced time-trial completion time relative to placebo.”
Quoted verbatim from Dose-Response Effect of Oral Caffeine Use on Aerobic Exercise Performance: A Systematic Review and Meta-Analysis.. - Study
- meta-analysis
- Dose
- Acute pre-exercise oral anhydrous caffeine; low (3 mg/kg or less) and moderate (4-6 mg/kg) dose strata
- Population
- Healthy adults aged 18-59 years performing aerobic time-trial tests
Dose-Response Effect of Oral Caffeine Use on Aerobic Exercise Performance: A Systematic Review and Meta-Analysis.2026PMID:42356375
magnesium(2+) — no detected effect on
PreliminaryGrade D, Preliminary. Non-human or in vitro only.FindingNull result“The time taken to complete the 10 km time trial was not different ( p = 0.89) between the placebo (1282 ± 126 s) and magnesium (1281 ± 97 s).”
Quoted verbatim from Short-Term Magnesium Supplementation Has Modest Detrimental Effects on Cycle Ergometer Exercise Performance and Skeletal Muscle Mitochondria and Negligible Effects on the Gut Microbiota: A Randomized Crossover Clinical Trial.. - Study
- crossover
- Participants
- 15
- Duration
- 9 days
- Dose
- magnesium chloride 300 mg (ReMag) twice per day for 9 days
- Population
- Healthy regularly exercising adults aged 18-40; primary outcome; self-paced simulated 10 km stationary cycle ergometer time trial
Short-Term Magnesium Supplementation Has Modest Detrimental Effects on Cycle Ergometer Exercise Performance and Skeletal Muscle Mitochondria and Negligible Effects on the Gut Microbiota: A Randomized Crossover Clinical Trial.2025PMID:40077784Industry funded