Compound
astaxanthin
A carotenone that consists of β,β-carotene-4,4'-dione bearing two hydroxy substituents at positions 3 and 3' (the 3S,3'S diastereomer). A carotenoid pigment found mainly in animals (crustaceans, echinoderms) but also occurring in plants. It can occur free (as a red pigment), as an ester, or as a blue, brown or green chromoprotein.
Definition from ChEBI (CHEBI:40968), read 2026-09-23. CC BY 4.0.
Studied for
26 endpoints · 35 findings · 16 papers · 12 null
- LDL cholesterolraisesEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.
- Systolic blood pressure (setting unspecified)lowersEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.
- Maximal oxygen uptakeno detected effectEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.
- Time-trial completion timeno detected effectEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.
- Interleukin-6 concentrationno detected effectEvidence strength: limited. Human evidence with several recorded weaknesses, or a design that tops out at limited.
Structure
Loading the model…
- Class
- Organic compound
- Formula
- C40H52O4
- Mass
- 596.852 g/mol
- Charge
- 0
- InChIKey
- MQZIGYBFDRPAKN-UWFIBFSHSA-N
- SMILES
- CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)C(=O)[C@@H](O)CC2(C)C)C(C)(C)C[C@H](O)C1=O
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What the evidence says
How to read these marks35 findings · 26 endpoints · 16 papers · 12 null · by evidence strength
- Evidence strength
- Strong
- Moderate
- Limited
- Very limited
- Insufficient
| Endpoint | Lowered13 findings, 8 endpoints | No detected effect12 findings, 12 endpoints | Raised4 findings, 4 endpoints | Other6 findings, 6 endpoints |
|---|---|---|---|---|
| LDL cholesterol | ||||
| Systolic blood pressure (setting unspecified) | ||||
| Interleukin-6 concentration | ||||
| Alanine aminotransferase | ||||
| Aspartate aminotransferase | ||||
| Tumour necrosis factor alpha concentration | ||||
| Activates NFE2L2 | ||||
| Body mass | ||||
| HDL cholesterol | ||||
| Inhibits CCR7 | ||||
| Inhibits STAT3 | ||||
| Serum creatine kinase activity | ||||
| Activates STING1 | ||||
| Binds TNFRSF1B | ||||
| Inhibits KEAP1 | ||||
| Serum creatinine concentration | ||||
| Serum uric acid | ||||
| Time to exhaustion | ||||
| Measured, and no finding detected an effect | ||||
| Maximal oxygen uptake | ||||
| Time-trial completion time | ||||
| Body mass index | ||||
| C-reactive protein concentration | ||||
| Diastolic blood pressure (setting unspecified) | ||||
| Fasting blood glucose | ||||
| Glycated haemoglobin (HbA1c) | ||||
| Total testosterone | ||||
What moved
23 findings
Increases LDL cholesterol
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“However, AST significantly increased the level of LDL-C (MD = 0.64; 95% CI = 0.64, 0.89; I2 = 0%; p < 0.00001;, regardless the duration of consumption and dosage of administration (Supplementary File S6 Figure S8a,b).”
Quoted verbatim from Astaxanthin Influence on Health Outcomes of Adults at Risk of Metabolic Syndrome: A Systematic Review and Meta-Analysis.. - Study
- meta-analysis
- Population
- adults with metabolic syndrome risk factors (CTS, T2DM, obesity, hypertension, renal transplant recipients); meta-analysis pooling 7 RCTs
Effect 0.64 mean difference, 95% CI 0.64 to 0.89
Astaxanthin Influence on Health Outcomes of Adults at Risk of Metabolic Syndrome: A Systematic Review and Meta-Analysis.2022PMID:35631193Permalink
Decreases systolic blood pressure (setting unspecified)
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“Subgroup analysis exhibited that the SBP was reduced significantly when AST was administered for more than 8 weeks (MD = −4.69; 95% CI = −9.23, −0.16; I2 = 0%; p = 0.04) (Supplementary File S6 Figure S4a).”
Quoted verbatim from Astaxanthin Influence on Health Outcomes of Adults at Risk of Metabolic Syndrome: A Systematic Review and Meta-Analysis.. - Study
- meta-analysis
- Population
- adults with metabolic syndrome risk factors; subgroup: AST administered for more than 8 weeks (pooled meta-analysis subgroup)
Effect -4.69 mean difference, 95% CI -9.23 to -0.16
Astaxanthin Influence on Health Outcomes of Adults at Risk of Metabolic Syndrome: A Systematic Review and Meta-Analysis.2022PMID:35631193Permalink
Decreases aspartate aminotransferase
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×2“Serum levels of aspartate transaminase (AST) and alanine transaminase (ALT) were higher in ethanol-fed mice than pair-fed mice, but these values were decreased in ethanol with AXT-fed mice.”
Quoted verbatim from Astaxanthin alleviated ethanol-induced liver injury by inhibition of oxidative stress and inflammatory responses via blocking of STAT3 activity.. - Study
- animal · not in humans
- Duration
- 10 days
- Dose
- 0.2, 2 or 20 mg/kg daily by oral gavage in olive oil
- Population
- Male C57BL/6 mice (n = 8 per group) on a chronic-plus-binge ethanol model; AXT 0.2, 2 or 20 mg/kg by oral gavage for 10 days versus ethanol-fed mice without AXT
Astaxanthin alleviated ethanol-induced liver injury by inhibition of oxidative stress and inflammatory responses via blocking of STAT3 activity.2018PMID:30237578Permalink
Decreases interleukin-6 concentration
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×1“The results showed that administration of astaxanthin significantly decreased the production of TNF-α, IL-6, and IL-10.”
Quoted verbatim from Astaxanthin Protects Dendritic Cells from Lipopolysaccharide-Induced Immune Dysfunction.. - Study
- animal · not in humans
- Population
- LPS-challenged C57BL/6 mice, serum cytokines measured by ELISA 4 h after LPS injection
Astaxanthin Protects Dendritic Cells from Lipopolysaccharide-Induced Immune Dysfunction.2021PMID:34204220Permalink
Decreases serum creatine kinase activity
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“Similarly, administration of ASX decreased the CK levels in swimming training mice.”
Quoted verbatim from High-Dose Astaxanthin Supplementation Suppresses Antioxidant Enzyme Activity during Moderate-Intensity Swimming Training in Mice.. - Study
- animal · not in humans
- Duration
- 4 weeks
- Dose
- 5, 15 or 30 mg/kg body weight daily by oral gavage in olive oil, two hours before swimming
- Population
- Male C57BL/6 mice (n = 8 per group) given moderate-intensity swimming training for four weeks; ASX at 5, 15 and 30 mg/kg BW by gavage in olive oil versus swimming controls given olive oil; plasma CK
High-Dose Astaxanthin Supplementation Suppresses Antioxidant Enzyme Activity during Moderate-Intensity Swimming Training in Mice.2019PMID:31159211Permalink
Inhibits STAT3
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“Furthermore, ethanol-induced p-STAT3 expression was lowered in ethanol with AXT-fed mice than ethanol-fed mice.”
Quoted verbatim from Astaxanthin alleviated ethanol-induced liver injury by inhibition of oxidative stress and inflammatory responses via blocking of STAT3 activity.. - Study
- animal · not in humans
- Duration
- 10 days
- Dose
- 0.2, 2 or 20 mg/kg daily by oral gavage for 10 days
- Population
- Male C57BL/6 mice on a chronic-plus-binge ethanol model; liver phospho-STAT3 by Western blot, AXT-fed versus ethanol-fed
Astaxanthin alleviated ethanol-induced liver injury by inhibition of oxidative stress and inflammatory responses via blocking of STAT3 activity.2018PMID:30237578Permalink
Show the remaining 17
Increases body mass
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“However, the body weight of mice that received 25-100 mg/kg ATX was significantly increased compared to that of the TBI groups.”
Quoted verbatim from Astaxanthin attenuates total body irradiation-induced hematopoietic system injury in mice via inhibition of oxidative stress and apoptosis.. - Study
- animal · not in humans
- Duration
- 12 days
- Dose
- 25, 50 or 100 mg/kg by oral gavage from 3 days before to 7 days after irradiation
- Population
- Male C57BL/6 mice given 4 Gy total body irradiation; ATX 25, 50 or 100 mg/kg versus DMSO vehicle, weighed 12 days after irradiation (N = 5 per group)
Astaxanthin attenuates total body irradiation-induced hematopoietic system injury in mice via inhibition of oxidative stress and apoptosis.2017PMID:28115023Permalink
Decreases aspartate aminotransferase
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×2“In addition, the levels of AST and ALT were elevated, and were effectively reduced in the ASTX group compared with the IR group.”
Quoted verbatim from Astaxanthin prevents ischemia-reperfusion injury of the steatotic liver in mice.. - Study
- animal · not in humans
- Duration
- 2 days
- Dose
- 25 mg/kg by oral gavage three times, at 48 h, 24 h and 40 min before ischemia
- Population
- Male C57BL/6 mice with diet-induced steatotic liver (methionine- and choline-deficient high-fat diet, 21 days), 15 min ischemia and 3 h reperfusion; ASTX versus olive oil by gavage before ischemia-reperfusion
Astaxanthin prevents ischemia-reperfusion injury of the steatotic liver in mice.2017PMID:29121675Permalink
Decreases alanine aminotransferase
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×2“Following ASX treatment (30 mg/kg or 60 mg/kg), ALT and AST decreased in a dose-dependent manner.”
Quoted verbatim from Astaxanthin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy via the ROS/MAPK Pathway in Mice.. - Study
- animal · not in humans
- Duration
- 14 days
- Dose
- 30 mg/kg or 60 mg/kg for 14 days before ischemia reperfusion
- Population
- Mice with hepatic ischemia reperfusion injury, pretreated with astaxanthin 30 or 60 mg/kg for 14 days, compared with the untreated ischemia reperfusion group
Astaxanthin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy via the ROS/MAPK Pathway in Mice.2015PMID:26023842Permalink
Decreases alanine aminotransferase
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×2“Serum levels of aspartate transaminase (AST) and alanine transaminase (ALT) were higher in ethanol-fed mice than pair-fed mice, but these values were decreased in ethanol with AXT-fed mice.”
Quoted verbatim from Astaxanthin alleviated ethanol-induced liver injury by inhibition of oxidative stress and inflammatory responses via blocking of STAT3 activity.. - Study
- animal · not in humans
- Duration
- 10 days
- Dose
- 0.2, 2 or 20 mg/kg daily by oral gavage in olive oil
- Population
- Male C57BL/6 mice (n = 8 per group) on a chronic-plus-binge ethanol model; AXT 0.2, 2 or 20 mg/kg by oral gavage for 10 days versus ethanol-fed mice without AXT
Astaxanthin alleviated ethanol-induced liver injury by inhibition of oxidative stress and inflammatory responses via blocking of STAT3 activity.2018PMID:30237578Permalink
Decreases aspartate aminotransferase
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×2“Following ASX treatment (30 mg/kg or 60 mg/kg), ALT and AST decreased in a dose-dependent manner.”
Quoted verbatim from Astaxanthin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy via the ROS/MAPK Pathway in Mice.. - Study
- animal · not in humans
- Duration
- 14 days
- Dose
- 30 mg/kg or 60 mg/kg for 14 days before ischemia reperfusion
- Population
- Mice with hepatic ischemia reperfusion injury, pretreated with astaxanthin 30 or 60 mg/kg for 14 days, compared with the untreated ischemia reperfusion group
Astaxanthin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy via the ROS/MAPK Pathway in Mice.2015PMID:26023842Permalink
Decreases interleukin-6 concentration
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×1“Astaxanthin significantly reduced blood interleukin-6 concentration in T2DM patients (weighted mean difference: -0.70 pg/mL; 95% CI, -1.29 to -0.11 pg/mL; P = .02).”
Quoted verbatim from Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers: a systematic review and meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- type 2 diabetes mellitus (T2DM) patients; meta-analysis subgroup within the pooled 12-RCT synthesis
Effect -0.7 mean difference, 95% CI -1.29 to -0.11
Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers: a systematic review and meta-analysis of randomized controlled trials.2022PMID:35091276Permalink
Activates NFE2L2
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“As shown in Figure 8A–D, treatment of LPS-induced DCs with astaxanthin, HO-1, and Nrf2 were significantly upregulated, compared with the LPS-only group.”
Quoted verbatim from Astaxanthin Protects Dendritic Cells from Lipopolysaccharide-Induced Immune Dysfunction.. - Study
- in vitro · not in humans
- Population
- LPS-induced murine bone-marrow-derived dendritic cells
Astaxanthin Protects Dendritic Cells from Lipopolysaccharide-Induced Immune Dysfunction.2021PMID:34204220Permalink
Decreases alanine aminotransferase
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×2“In addition, the levels of AST and ALT were elevated, and were effectively reduced in the ASTX group compared with the IR group.”
Quoted verbatim from Astaxanthin prevents ischemia-reperfusion injury of the steatotic liver in mice.. - Study
- animal · not in humans
- Duration
- 2 days
- Dose
- 25 mg/kg by oral gavage three times, at 48 h, 24 h and 40 min before ischemia
- Population
- Male C57BL/6 mice with diet-induced steatotic liver (methionine- and choline-deficient high-fat diet, 21 days), 15 min ischemia and 3 h reperfusion; ASTX versus olive oil by gavage before ischemia-reperfusion
Astaxanthin prevents ischemia-reperfusion injury of the steatotic liver in mice.2017PMID:29121675Permalink
Inhibits CCR7
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“With LPS treatment alone, CCR7 expression was significantly increased, whereas they remarkably declined after the treatment of astaxanthin.”
Quoted verbatim from Astaxanthin Protects Dendritic Cells from Lipopolysaccharide-Induced Immune Dysfunction.. - Study
- in vitro · not in humans
- Population
- LPS-induced murine bone-marrow-derived dendritic cells
Astaxanthin Protects Dendritic Cells from Lipopolysaccharide-Induced Immune Dysfunction.2021PMID:34204220Permalink
Increases HDL cholesterol
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“In summary, our systematic review and meta-analysis revealed that astaxanthin consumption was associated with increase in HDL-C and decrease in CRP.”
Quoted verbatim from The effects of astaxanthin supplementation on obesity, blood pressure, CRP, glycemic biomarkers, and lipid profile: A meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- adults; meta-analysis of randomized controlled trials of astaxanthin supplementation (14 studies)
The effects of astaxanthin supplementation on obesity, blood pressure, CRP, glycemic biomarkers, and lipid profile: A meta-analysis of randomized controlled trials.2020PMID:32755613Permalink
Binds TNFRSF1B
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Finding“Notably, astaxanthin selectively binds to TNFR2 in oocytes, thereby preventing TNFR2 from interacting with TNF-α and inhibiting the activation of the TNF signaling pathway within oocytes.”
Quoted verbatim from Astaxanthin prevents postovulatory oocyte aging by targeting TNFR2 and inhibiting the TNF signaling pathway.. - Study
- ex vivo · not in humans
- Population
- Mouse postovulatory MII oocytes cultured in vitro
Astaxanthin prevents postovulatory oocyte aging by targeting TNFR2 and inhibiting the TNF signaling pathway.2025PMID:40598379Permalink
Decreases tumour necrosis factor alpha concentration
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Finding“The results showed that administration of astaxanthin significantly decreased the production of TNF-α, IL-6, and IL-10.”
Quoted verbatim from Astaxanthin Protects Dendritic Cells from Lipopolysaccharide-Induced Immune Dysfunction.. - Study
- animal · not in humans
- Population
- LPS-challenged C57BL/6 mice, serum cytokines measured by ELISA 4 h after LPS injection
Astaxanthin Protects Dendritic Cells from Lipopolysaccharide-Induced Immune Dysfunction.2021PMID:34204220Permalink
Decreases serum uric acid
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Finding“Also, AST significantly reduced the amount of creatinine, urea, and uric acid in the serum and improved the activity of SOD and catalase in the kidney tissue (p < 0.05).”
Quoted verbatim from Astaxanthin prevents nephrotoxicity through Nrf2/HO-1 pathway.. - Study
- animal · not in humans
- Duration
- 10 days
- Dose
- 25, 50, or 75 mg/kg astaxanthin during the 10-day course, alongside MTX 10 mg/kg on days 6, 8, 10
- Population
- male Wistar rats with methotrexate-induced nephrotoxicity
Astaxanthin prevents nephrotoxicity through Nrf2/HO-1 pathway.2024PMID:37683291Permalink
Inhibits KEAP1
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Finding“Additionally, ASX could inhibit the expression of Keap1, promote the transport of Nrf2 from cytoplasm to nucleus and facilitate the expressions of HO-1, NQO1, γ-glutamylcysteine synthetase, (γ-GCS) and GPx.”
Quoted verbatim from Astaxanthin inhibits oxidative stress and apoptosis in diabetic retinopathy.. - Study
- animal · not in humans
- Duration
- 6 weeks
- Dose
- 20 mg/kg for 45 days
- Population
- streptozotocin-induced diabetic retinopathy rats, retinal tissue
Astaxanthin inhibits oxidative stress and apoptosis in diabetic retinopathy.2023PMID:37343496Permalink
Increases time to exhaustion
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Finding“The elapsed time until exhaustion of forced-swimming activity was 29% higher in ASTA-fed animals (48.2 ± 14.1 min) than in control (37.4 ± 4.0 min), as shown by boxplots in Figure 2.”
Quoted verbatim from Astaxanthin supplementation delays physical exhaustion and prevents redox imbalances in plasma and soleus muscles of Wistar rats.. - Study
- animal · not in humans
- Duration
- 6 weeks
- Dose
- 1 mg ASTA/kg body weight for 45 days
- Population
- Wistar rats swimming to exhaustion with an additional load of 5% body weight, after 45 days of supplementation
Astaxanthin supplementation delays physical exhaustion and prevents redox imbalances in plasma and soleus muscles of Wistar rats.2014PMID:25514562Industry fundedPermalink
Activates STING1
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Finding“Mechanistically, astaxanthin inhibited HSV-1 infection and oxidative stress-induced STING carbonylation and consequently promoted STING translocation to the Golgi apparatus and oligomerization, which activated STING-dependent host defenses.”
Quoted verbatim from Astaxanthin Inhibits STING Carbonylation and Enhances Antiviral Responses.. - Study
- animal · not in humans
- Population
- C57BL/6J mice and mouse primary peritoneal macrophages infected with HSV-1
Astaxanthin Inhibits STING Carbonylation and Enhances Antiviral Responses.2024PMID:38391298Permalink
Decreases serum creatinine concentration
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Finding“Also, AST significantly reduced the amount of creatinine, urea, and uric acid in the serum and improved the activity of SOD and catalase in the kidney tissue (p < 0.05).”
Quoted verbatim from Astaxanthin prevents nephrotoxicity through Nrf2/HO-1 pathway.. - Study
- animal · not in humans
- Duration
- 10 days
- Dose
- 25, 50, or 75 mg/kg astaxanthin during the 10-day course, alongside MTX 10 mg/kg on days 6, 8, 10
- Population
- male Wistar rats with methotrexate-induced nephrotoxicity
Astaxanthin prevents nephrotoxicity through Nrf2/HO-1 pathway.2024PMID:37683291Permalink
What did not
12 findings
No detected effect on maximal oxygen uptake
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“The pooled effect indicated no significant improvement in VO2max with astaxanthin supplementation compared with control (SMD = −0.14, 95% CI: −0.78 to 0.50), and heterogeneity was considerable (I2 = 83.1%).”
Quoted verbatim from The Effects of Astaxanthin Supplementation on Exercise Recovery Biomarkers and Exercise Performance: A Systematic Review and Meta-Analysis.. - Study
- meta-analysis
- Population
- healthy adults and athletes; meta-analysis pooling 9 RCT comparisons
Effect -0.14 standardised mean difference, 95% CI -0.78 to 0.5
The Effects of Astaxanthin Supplementation on Exercise Recovery Biomarkers and Exercise Performance: A Systematic Review and Meta-Analysis.2026PMID:42197030Industry fundedPermalink
No detected effect on time-trial completion time
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“The pooled estimate showed no significant effect of astaxanthin supplementation on time-trial performance (SMD = −0.17, 95% CI: −0.76 to 0.42), with moderate heterogeneity (I2 = 43.7%).”
Quoted verbatim from The Effects of Astaxanthin Supplementation on Exercise Recovery Biomarkers and Exercise Performance: A Systematic Review and Meta-Analysis.. - Study
- meta-analysis
- Population
- healthy adults and athletes; meta-analysis pooling 3 RCT comparisons
Effect -0.17 standardised mean difference, 95% CI -0.76 to 0.42
The Effects of Astaxanthin Supplementation on Exercise Recovery Biomarkers and Exercise Performance: A Systematic Review and Meta-Analysis.2026PMID:42197030Industry fundedPermalink
No detected effect on interleukin-6 concentration
LimitedEvidence strength: limited. Human evidence with several recorded weaknesses, or a design that tops out at limited.FindingNull result“The pooled effect showed no statistically significant influence of astaxanthin supplementation on IL-6 (SMD = −0.23, 95% CI: −0.65 to 0.20), and statistical heterogeneity was absent (I2 = 0.0%).”
Quoted verbatim from The Effects of Astaxanthin Supplementation on Exercise Recovery Biomarkers and Exercise Performance: A Systematic Review and Meta-Analysis.. - Study
- meta-analysis
- Population
- healthy adults and athletes; meta-analysis pooling 3 RCT comparisons
Effect -0.23 standardised mean difference, 95% CI -0.65 to 0.2
The Effects of Astaxanthin Supplementation on Exercise Recovery Biomarkers and Exercise Performance: A Systematic Review and Meta-Analysis.2026PMID:42197030Industry fundedPermalink
No detected effect on tumour necrosis factor alpha concentration
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“The effects of astaxanthin on blood C-reactive protein and tumor necrosis factor-α concentrations were not significant.”
Quoted verbatim from Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers: a systematic review and meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- adults, including type 2 diabetes mellitus (T2DM) patients; meta-analysis pooling 12 RCTs
Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers: a systematic review and meta-analysis of randomized controlled trials.2022PMID:35091276Permalink
No detected effect on total testosterone
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“On the other hand, Olucan et al. (2021) did not observe any significant changes in testosterone levels in a formaldehyde toxicity model.”
Quoted verbatim from A systematic review and meta-analysis of astaxanthin efficacy in male infertility: evidence from clinical and preclinical studies.. - Study
- animal · not in humans
- Duration
- 14 days
- Dose
- 16 and 32 mg/kg, 14 days (Table 4)
- Population
- Wistar Albino rats; formaldehyde-induced testicular injury model (Ulucan et al. 2021)
A systematic review and meta-analysis of astaxanthin efficacy in male infertility: evidence from clinical and preclinical studies.2026PMID:41714744Permalink
No detected effect on C-reactive protein concentration
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“The effects of astaxanthin on blood C-reactive protein and tumor necrosis factor-α concentrations were not significant.”
Quoted verbatim from Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers: a systematic review and meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- adults, including type 2 diabetes mellitus (T2DM) patients; meta-analysis pooling 12 RCTs
Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers: a systematic review and meta-analysis of randomized controlled trials.2022PMID:35091276Permalink
Show the remaining 6
No detected effect on diastolic blood pressure (setting unspecified)
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“Current study revealed that astaxanthin consumption was not associated with FBS, HbA1c, TC, LDL-C, TG, BMI, BW, DBP, and SBP.”
Quoted verbatim from The effects of astaxanthin supplementation on obesity, blood pressure, CRP, glycemic biomarkers, and lipid profile: A meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- adults; meta-analysis of randomized controlled trials of astaxanthin supplementation (14 studies)
The effects of astaxanthin supplementation on obesity, blood pressure, CRP, glycemic biomarkers, and lipid profile: A meta-analysis of randomized controlled trials.2020PMID:32755613Permalink
No detected effect on systolic blood pressure (setting unspecified)
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“Current study revealed that astaxanthin consumption was not associated with FBS, HbA1c, TC, LDL-C, TG, BMI, BW, DBP, and SBP.”
Quoted verbatim from The effects of astaxanthin supplementation on obesity, blood pressure, CRP, glycemic biomarkers, and lipid profile: A meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- adults; meta-analysis of randomized controlled trials of astaxanthin supplementation (14 studies)
The effects of astaxanthin supplementation on obesity, blood pressure, CRP, glycemic biomarkers, and lipid profile: A meta-analysis of randomized controlled trials.2020PMID:32755613Permalink
No detected effect on body mass index
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“Current study revealed that astaxanthin consumption was not associated with FBS, HbA1c, TC, LDL-C, TG, BMI, BW, DBP, and SBP.”
Quoted verbatim from The effects of astaxanthin supplementation on obesity, blood pressure, CRP, glycemic biomarkers, and lipid profile: A meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- adults; meta-analysis of randomized controlled trials of astaxanthin supplementation (14 studies)
The effects of astaxanthin supplementation on obesity, blood pressure, CRP, glycemic biomarkers, and lipid profile: A meta-analysis of randomized controlled trials.2020PMID:32755613Permalink
No detected effect on fasting blood glucose
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“Current study revealed that astaxanthin consumption was not associated with FBS, HbA1c, TC, LDL-C, TG, BMI, BW, DBP, and SBP.”
Quoted verbatim from The effects of astaxanthin supplementation on obesity, blood pressure, CRP, glycemic biomarkers, and lipid profile: A meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- adults; meta-analysis of randomized controlled trials of astaxanthin supplementation (14 studies)
The effects of astaxanthin supplementation on obesity, blood pressure, CRP, glycemic biomarkers, and lipid profile: A meta-analysis of randomized controlled trials.2020PMID:32755613Permalink
No detected effect on glycated haemoglobin (HbA1c)
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“Current study revealed that astaxanthin consumption was not associated with FBS, HbA1c, TC, LDL-C, TG, BMI, BW, DBP, and SBP.”
Quoted verbatim from The effects of astaxanthin supplementation on obesity, blood pressure, CRP, glycemic biomarkers, and lipid profile: A meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- adults; meta-analysis of randomized controlled trials of astaxanthin supplementation (14 studies)
The effects of astaxanthin supplementation on obesity, blood pressure, CRP, glycemic biomarkers, and lipid profile: A meta-analysis of randomized controlled trials.2020PMID:32755613Permalink
No detected effect on LDL cholesterol
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“Current study revealed that astaxanthin consumption was not associated with FBS, HbA1c, TC, LDL-C, TG, BMI, BW, DBP, and SBP.”
Quoted verbatim from The effects of astaxanthin supplementation on obesity, blood pressure, CRP, glycemic biomarkers, and lipid profile: A meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- adults; meta-analysis of randomized controlled trials of astaxanthin supplementation (14 studies)
The effects of astaxanthin supplementation on obesity, blood pressure, CRP, glycemic biomarkers, and lipid profile: A meta-analysis of randomized controlled trials.2020PMID:32755613Permalink
What it touches on the way
Mechanistic reach
5 entities
5 entities reached.
0 reported hops5 assembled from the scaffold
- STAT3ProteinUNIPROT:P40763inhibitsInferred only37 paths37 endpoints
- CCR7ProteinUNIPROT:P32248inhibitsInferred only29 paths29 endpoints
- NFE2L2ProteinUNIPROT:Q16236activatesInferred only23 paths23 endpoints
- STING1ProteinUNIPROT:Q86WV6activatesInferred only11 paths11 endpoints
- KEAP1ProteinUNIPROT:Q14145inhibitsInferred only4 paths4 endpoints
Reactions
1 reaction
CHEBI:80217+2AH2+2dioxygenastaxanthin+2A+3water
Reaction pageDirection not assertedBalanced
Rhea RHEA:56772CC BY 4.0Reference data
On the label
Labelled products
726 products
Source: NIH DSLD · Ingredient: astaxanthin · 726 products · Declared amount per serving: 0.25–1,000 mg (425 products)
721 labels state an amount5 do not
- 1MDKrillMD2 mgper 2 Softgel(s)DSLD:246767
- 1MDMoveMD2 mgper 1 Capsule(s)DSLD:246770
- 1MDVisionMDAlgae Extract4 mgper 1 Softgel(s)DSLD:274806
- 1MD NutritionKrillMD2 mgper 2 Softgel(s)DSLD:274801
- 1MD NutritionMoveMDAstaxanthin, Natural2 mgper 1 Capsule(s)DSLD:274803
- 1MD NutritionVisionMDHaematococcus pluvialis Algae Extract4 mgper 1 Softgel(s)DSLD:309827
- A.C. Grace CompanyUNIQUE Krill+100 mcgper 2 Softgel(s)DSLD:285415
- Advanced Nutrition by ZahlerMulti Vitamin Beauty3 mgper 1 Capsule(s)DSLD:260484
- AdvoCareAmplify A.T.Astaxanthin · Astaxanthin (Form: as part of a natural complex including Astaxanthin, Lutein, Beta Carotene, Canthaxanthin, and other carotenoids from Haematococcus pluvialis Algae extract Genus: Haematococcus Species: pluvialis)4 mgper 1 Softgel(s)DSLD:177470
- AdvoCareGlow Skinamount not statedper 1 Softgel(s)DSLD:265478
- Allergy Research GroupAstaxanthin 12 mg12 mgper 1 Softgel(s)DSLD:317587
- Allergy Research GroupAstaxanthin 6 mg6 mgper 1 Softgel(s)DSLD:257978
Show the remaining 714
- AN Amazing Nutrition Amazing OmegaKrill Oil 1,000 mg750 mcgper 2 Softgel(s)DSLD:251700
- AN Amazing Nutrition Amazing OmegaKrill Oil 500 mg43 mcgper 1 Softgel(s)DSLD:251769
- Ancient NutritionOmegas Whole BodyHaematococcus pluvialis4 mgper 3 Softgel(s)DSLD:305773
- Antler FarmsAntarctic Krill Oil200 mcgper 2 Softgel(s)DSLD:325604
- AOR Advanced Orthomolecular Research AdvancedVision Support IIHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)4 mgper 2 Softgel(s)DSLD:214695
- AOR Advanced Orthomolecular Research PremiumAstaxanthin 20 mgHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)20 mgper 1 Vegetarian Softgel(s)DSLD:214431
- Approved ScienceAntarctic Krill Oil 2000 mg650 mcgper 1 Softgel(s)DSLD:319716
- Approved ScienceAstaxanthin +BioPerineAstaxanthin · organic microalgae12 mgper 1 Capsule(s)DSLD:319722
- Approved ScienceEyesyl +BioPerineAstaxanthin · from organic Haematococcus pluvialis microalgae4 mgper 1 Capsule(s)DSLD:319753
- aProvenProductBlack Label Krill Oil2.5 mgper 2 Softgel(s)DSLD:29802
- Arctic OilsOmegaPure KrillMicroalgae · Astaxanthin (Form: from Microalgae Genus: Haematococcus Species: pluvialis)2 mgper 2 Softgel(s)DSLD:240414
- aSquared NutritionAstaxanthin 10 mgHaematococcus pluvialis Extract · yielding 5% potency10 mgper 1 Softgel(s)DSLD:263843
- Barlean'sAlaskan Salmon OilMarine Algae · Astaxanthin (Form: from Marine Algae)500 mcgper 3 Softgel(s)DSLD:59285
- Barlean'sWild & Whole Krill Oil100 mcgper 2 Softgel(s)DSLD:56239
- Barlean'sWild & Whole Krill Oil100 mcgper 2 Softgel(s)DSLD:59731
- Barlean's Organic OilsWild & Whole Krill Oil100 mcgper 2 Softgel(s)DSLD:47134
- Barlean's Seriously DeliciousEye Remedy Tangerine SmoothieHaematococcus pluvialis2 mgper 15.9 Gram(s)DSLD:337680
- Barlean's Seriously DeliciousOmega Pals Hooty Fuity Tangerine FlavorHaematococcus pluvialis1 mgper 7.95 mLDSLD:291843
- BayerArctic Wonder Omega-3 Krill Oil1 mgper 2 Softgel(s)DSLD:12238
- Bel-Air Nutrition CorpAstaxanthin 12 mg12 mgper 2 Capsule(s)DSLD:277567
- Best NaturalsAstaxanthin 12 mgHaematococcus pluvialis microalgae12 mgper 1 Softgel(s)DSLD:269239
- Best NaturalsKrill-1000 1000 mg1 mgper 1 Softgel(s)DSLD:306002
- Best NaturalsKrill-1000 mg1 mgper 1 Softgel(s)DSLD:270592
- Best NaturalsKrill-1250 mg1.25 mgper 1 Softgel(s)DSLD:270595
- Best NaturalsKrill-500 1000 mg1 mgper 1 Softgel(s)DSLD:270590
- Best NaturalsKrill-500 500 mg1 mgper 2 Softgel(s)DSLD:269778
- Best NaturalsKrill-500 500 mg1 mgper 2 Softgel(s)DSLD:270589
- Big Bold HealthFire and IceHawaiian H. pluvialis · naturally occurring3.2 mgper 4 Softgel(s)DSLD:276679
- Big Bold HealthOmega-3 Rejuvenate3.64 mcgper 2 Softgel(s)DSLD:320017
- Big Bold HealthSkin & Eye Support4 mgper 2 Softgel(s)DSLD:320018
- Bio NutritionK Bio Krill 500 mg500 mcgper 1 Softgel(s)DSLD:200593
- BioAstinBioAstin 12 mgHaematococcus pluvialis12 mgper 1 Softgel(s)DSLD:295248
- BioAstinEyeAstinHaematococcus pluvialis · natural Astaxanthin (Form: from Haematococcus pluvialis PlantPart: microalgae Genus: Haematococcus Species: pluvialis)6 mgper 2 Soft Gel(s)DSLD:241899
- BioAstinEyeAstin Hawaiian Astaxanthin 6 mgHaematococcus pluvialis6 mgper 2 Softgel(s)DSLD:320596
- BioAstinHawaiian AstaxanthinHaematococcus pluvialis12 mgper 1 Softgel(s)DSLD:259686
- BioAstinHawaiian Astaxanthin 12 mgHaematococcus pluvialis12 mgper 1 Softgel(s)DSLD:259687
- BioAstinHawaiian Astaxanthin 12 mgHaematococcus pluvialis12 mgper 1 Softgel(s)DSLD:295249
- BioAstinHawaiian Astaxanthin 12 mgHaematococcus pluvialis12 mgper 1 Softgel(s)DSLD:320597
- BioAstinHawaiian Astaxanthin 4 mgHaematococcus pluvialis12 mgper 1 Softgel(s)DSLD:259692
- BioAstinHawaiian Astaxanthin 4 mgHaematococcus pluvialis12 mgper 3 Vegan Softgel(s)DSLD:295252
- BioAstinHawaiian Astaxanthin 4 mgHaematococcus pluvialis12 mgper 1 Softgel(s)DSLD:320598
- BioAstinOmegaAstinHaematococcus pluvialis · natural Astaxanthin (Form: from Haematococcus pluvialis PlantPart: microalgae Genus: Haematococcus Species: pluvialis)8 mgper 2 Vegan Softgel(s)DSLD:241925
- BioAstinSupreme Hawaiian Astaxanthin 6 mgHaematococcus pluvialis12 mgper 1 Vegan Softgel(s)DSLD:320600
- BioAstinTurmeric Astin Hawaiian Astaxanthin 6 mgHaematococcus pluvialis6 mgper 1 Vegan Softgel(s)DSLD:320601
- BioAstinVegan Hawaiian Astaxanthin 12 mgHaematococcus pluvialis12 mgper 1 Softgel(s)DSLD:259690
- BioAstinVegan Hawaiian Astaxanthin 12 mgHaematococcus pluvialis12 mgper 1 Softgel(s)DSLD:259691
- BioCareEyeCare Plus2 mgper 1 Capsule(s)DSLD:302207
- BioEmblemKrill Oill 1000 mg400 mcgper 2 Softgel(s)DSLD:337371
- BiophixMaximum Strength Retinal SupportHaematococcus pluvialis25 mcgper 1 Softgel(s)DSLD:276074
- BioTrustOmegaKrill 5XHaematococcus pluvialis Algae extract · AstaREAL Astaxanthin (Form: from Haematococcus pluvialis Algae extract Genus: Haematococcus Species: pluvialis)300 mcgper 3 Softgel(s)DSLD:206732
- BIOVEAAstaxanthin 4 mg4 mgper 1 Softgel(s)DSLD:248952
- BIOVEAHair, Skin & Nails250 mcgper 2 Vegetarian Capsule(s)DSLD:277880
- BluebonnetAstaxanthin 4 mgHaematococcus pluvialis Extract · Astaxanthin (Form: from Haematococcus pluvialis extract Genus: Haematococcus Species: pluvialis)4 mgper 1 Vegetarian Softgel(s)DSLD:178719
- BluebonnetAstaxanthin 4 mgHaematococcus pluvialis Extract · Astaxanthin (Form: from Haematococcus pluvialis extract Genus: Haematococcus Species: pluvialis)4 mgper 1 Vegetarian Softgel(s)DSLD:178721
- Bluebonnet Beautiful AllyAstaxanthinHaematococcus pluvialis Extract4 mgper 1 Vegetarian Softgel(s)DSLD:279743
- Bluebonnet Beautiful AllyAstaxanthinHaematococcus pluvialis Extract4 mgper 1 Vegetarian Softgel(s)DSLD:279741
- Blueprint Bryan JohnsonEssential SoftgelHaematococcus pluvialis12 mgper 1 Veggie Softgel(s)DSLD:328205
- BodSmithAstaxanthin 10 mgHaematococcus pluvialis10 mgper 2 Capsule(s)DSLD:252172
- Body Dynamics MaXzorbceuticals NutritionNu Born Skin12 mgper 3 Capsule(s)DSLD:292665
- BodyHealthOmega 3 HealthHaematococcus pluvialis4 mgper 2 Softgel(s)DSLD:322555
- BronsonAntarctic Krill Oil 1000 mg200 mcgper 2 Softgel(s)DSLD:232963
- BronsonAntarctic Krill Oil 1000 mg200 mcgper 2 Softgel(s)DSLD:257349
- BronsonAstaxanthin 4 mg4 mgper 1 Softgel(s)DSLD:8508
- Bronson LaboratoriesD-Cursinol Plus2.25 mgper 1 Capsule(s)DSLD:9068
- Bronson LaboratoriesD-Cursinol Plus2.25 mgper 1 Capsule(s)DSLD:9069
- Bronson LaboratoriesKrill Oil 500 mg1 mgper 2 Softgel(s)DSLD:33939
- Bronson LaboratoriesKrill Oil 500 mg1.5 mgper 2 Softgel(s)DSLD:8247
- Bronson LaboratoriesOpti-Relief6 mgper 1 Capsule(s)DSLD:8992
- Bruno MDRiboflamHaematococcus pluvialis4 mgper 3 Capsule(s)DSLD:259681
- BulkSupplements.comAstaxanthin Softgels12 mgper 1 Softgel(s)DSLD:294487
- BulkSupplements.comAstaxanthin Softgels12 mgper 1 Softgel(s)DSLD:294488
- BulkSupplements.comAstaxanthin Softgels 12 mg12 mgper 1 Softgel(s)DSLD:312651
- BulletproofEye ArmorGreen Algae · Astaxanthin (Form: from Green Algae Genus: Haematococus Species: pluvialis)4 mgper 1 Softgel(s)DSLD:213914
- California Academy of HealthAstaxanthinAlgae · Astaxanthin (Form: a natural extract from Algae (Form: Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)) (Alt. Name: Zanthin)4 mgper 1 Softgel(s)DSLD:191135
- California Academy of HealthPure Premium Antarctic Krill Oil 500 mgAstaxanthin Note: esterified1,000 mcgper 2 Softgel(s)DSLD:206422
- California Gold NutritionAstaCarotenoid ComplexHaematococcus pluvialis Microalgae Extract4 mgper 1 Softgel(s)DSLD:299577
- California Gold NutritionAstaxanthin 12 mgAstaxanthin12 mgper 1 Softgel(s)DSLD:274978
- California Gold NutritionAstaxanthin 12 mgHaematococcus pluvialis Extract12 mgper 1 Softgel(s)DSLD:299578
- California Gold NutritionAstaxanthin 12 mgHaematococcus pluvialis Extract12 mgper 1 Softgel(s)DSLD:318832
- California Gold NutritionCalanus Oil300 mcgper 1 Softgel(s)DSLD:299594
- CardaxZanthoSyn 12 mg12 mgper 1 Capsule(s)DSLD:243986
- CardaxZanthoSyn 12 mg12 mgper 1 Capsule(s)DSLD:243994
- CarlsonAstaxanthin Gummies 8 mg Natural Cherry FlavorAstaxanthin8 mgper 2 Gummy(ies)DSLD:306446
- CarlsonAstaxanthin Gummies 8 mg Natural Cherry FlavorAstaxanthin8 mgper 2 Gummy(ies)DSLD:337576
- CarlsonKid's Immune Boost Gummies Natural Cherry FlavorAstaxanthin4 mgper 1 Gummy(ies)DSLD:309279
- CarlsonSalmon Oil Complete4 mcgper 2 Softgel(s)DSLD:216625
- CarlsonSalmon Oil Complete4 mcgper 2 Softgel(s)DSLD:304885
- CarlsonSalmon Oil Complete8 mcgper 2 Soft Gel(s)DSLD:309276
- CarlsonSalmon Oil Complete4 mcgper 2 Softgel(s)DSLD:309277
- CarlsonVirgin Salmon Oil Complete4 mcgper 2 Softgel(s)DSLD:54865
- CarotecMitoDefense AstaKrillHaematococcus pluvialis Algae extract8 mgper 2 Softgel(s)DSLD:282136
- CATALOWild Red Sockeye Salmon Oil (Astaxanthin Added)Algae Extract · standardized 10%10 mgper 1 Softgel(s)DSLD:303050
- Chief OriginalsAstaxanthin Soft Gels 12 mgAstaxanthin, Natural12 mgper 1 Softgel(s)DSLD:307944
- ChildLife Clinicals Clinical FormulasEye-C Natural Cherry Berry FlavorAstaPure · Astaxanthin (Form: from AstaPure, Haematococcus pluvialis extract Genus: Haematococcus Species: pluvialis)2 mgper 1 Softgel(s)DSLD:241280
- CHK NutritionAstaxanthin 4 mgZanthin brand Haematococcus pluvialis extract · Astaxanthin (Form: from Zanthin brand Haematococcus pluvialis extract Genus: Haematococcus Species: pluvialis)4 mgper 1 Vegetarian Softgel(s)DSLD:228640
- CodeageBeauty Tonicorganic2 mgper 3 Capsule(s)DSLD:333460
- CodeageEyes Vitamins+Haematococcus pluvialis Algae Extract · from CO2 extract of Haematococcus pluvialis algae1 mgper 2 Capsule(s)DSLD:335353
- CodeageTeen Fermented Multivitamin+Algae360 mcgper 2 Capsule(s)DSLD:335407
- Country LifeAstaxanthin MAX 12 mgHaematococcus pluvialis Extract12 mgper 1 Softgel(s)DSLD:258907
- Country LifeCarotenoid ComplexHaematococcus pluvialis Extract · Astaxanthin (Form: from Haematococcus pluvialis extract Genus: Haematococcus Species: pluvialis) Note: 1 mg1,000 mcgper 1 Softgel(s)DSLD:181200
- Country LifeCarotenoid ComplexHaematococcus pluvialis Extract · 1 mg1,000 mcgper 1 Softgel(s)DSLD:333172
- Country LifeCarotenoid ComplexHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis) Note: (extract) (1 mg)1,000 mcgper 1 Softgel(s)DSLD:53430
- Crystal StarOmega 3 Krill Oil170 mcgper 2 Softgel(s)DSLD:243916
- CymbiotikaThe Omega Organic LemonHaematococcus pluvialis4 mgper 2 mLDSLD:253167
- DaVinci LaboratoriesAstaxanthin D3 LiquidHaematococcus pluvialis4 mgper 1 mLDSLD:288172
- DCAstaxanthin 5 mgHaematococcus pluvialis5 mgper 1 Softgel(s)DSLD:266822
- DCAstaxanthin 6 mgHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)6 mgper 1 Softgel(s)DSLD:244911
- DCAstaxanthin 6 mgHaematococcus pluvialis6 mgper 1 Softgel(s)DSLD:266821
- DCAstaxanthin 6 mgHaematococcus pluvialis6 mgper 1 Softgel(s)DSLD:266823
- DCAstaxanthin 6 mg6 mgper 1 Softgel(s)DSLD:266824
- DEKE & LAIFEAnti-Aging PrimeHaematococcus pluvialis4 mgper 3 Capsule(s)DSLD:277626
- Designs for HealthAstaxanthin 6 mgHaematococcus pluvialis Algae extract · Natural Astaxanthin (Form: from Haematococcus pluvialis Algae extract Genus: Haematococcus Species: pluvialis) (Alt. Name: AstaREAL(R))6 mgper 1 Softgel(s)DSLD:31942
- Designs for HealthXanthomega Krill OilHaematococcus pluvialis Algae extract12 mgper 2 Softgel(s)DSLD:262325
- Designs for HealthXanthOmega Krill OilHaematococcus pluvialis Algae extract · AstaREAL natural Astaxanthin (Form: from Haematococcus pluvialis Algae extract Genus: Haematococcus Species: pluvialis)12 mgper 2 Softgel(s)DSLD:23321
- Designs for HealthXanthOmega Krill OilHaematococcus pluvialis Algae extract · AstaREAL natural Astaxanthin (Form: from Haematococcus pluvialis Algae extract Genus: Haematococcus Species: pluvialis)12 mgper 2 Softgel(s)DSLD:23538
- Divine HealthLiving Krill 1000 mg200 mcgper 2 Softgel(s)DSLD:263014
- Doctor's BestAstaxanthinAstaPure · Natural Astaxanthin (Form: from AstaPure (Form: Solvent-free extract from Haematococcus pluvialis microalgae Genus: Haematococcus Species: pluvialis))6 mgper 2 Veggie Softgel(s)DSLD:59908
- Doctor's BestAstaxanthinAstaPure · Astaxanthin (Form: from AstaPure (Form: Solvent-free extract from Haematococcus pluvialis microalgae Genus: Haematococcus Species: pluvialis))6 mgper 2 Veggie Softgel(s)DSLD:59912
- Doctor's BestAstaxanthinAstaPure · Natural Astaxanthin (Form: from AstaPure (Form: Solvent-free extract from Haematococcus pluvialis microalgae Genus: Haematococcus Species: pluvialis))6 mgper 1 Veggie Softgel(s)DSLD:59917
- Doctor's BestAstaxanthin with AstaReal 6 mgAstaxanthin6 mgper 1 Veggie Softgel(s)DSLD:269631
- Doctor's BestAstaxanthin with AstaReal 6 mgAstaxanthin6 mgper 1 Veggie Softgel(s)DSLD:269659
- Doctor's BestBeauty CeramidesHaematococcus pluvialis microalgae6 mgper 1 Veggie Softgel(s)DSLD:269670
- Doctor's BestBest AstaxanthinHaematococcus pluvialis microalgae · Astaxanthin (Form: solvent-free extract from Haematococcus pluvialis microalgae Genus: Haematococcus Species: pluvialis) Note: (natural) (minimum)6 mgper 2 Softgel(s)DSLD:24322
- Doctor's BestBest AstaxanthinHaematococcus pluvialis microalgae · Astaxanthin (Form: solvent-free extract from Haematococcus pluvialis microalgae Genus: Haematococcus Species: pluvialis) Note: (natural) (minimum)6 mgper 2 Softgel(s)DSLD:59906
- Doctor's BestBest AstaxanthinHaematococcus pluvialis microalgae · Astaxanthin (Form: solvent-free extract from Haematococcus pluvialis microalgae Genus: Haematococcus Species: pluvialis) Note: (natural) (minimum)12 mgper 1 Softgel(s)DSLD:59907
- Doctor's BestReal KrillAstaxanthin Note: min.28 mcgper 1 Softgel(s)DSLD:63303
- doTERRAxEO MegaGreen Algae · Astapure Astaxanthin (Form: from Green Algae)1 mgper 4 Softgel(s)DSLD:203116
- doTERRAxEO MegaGreen Algae1 mgper 4 Softgel(s)DSLD:267715
- Double Wood SupplementsAstaxanthin 12 mgAstaxanthin12 mgper 1 Softgel(s)DSLD:315588
- Douglas Cooper Co.Astaxanthin 4 mgHaematococcus pluvialis Extract · Zanthin natural Astaxanthin (Form: from Haematococcus pluvialis extract Genus: Haematococcus Species: pluvialis)4 mgper 1 Softgel(s)DSLD:239502
- Douglas LaboratoriesAM Pack0.5 mgper 1 Packet(s)DSLD:230286
- Douglas LaboratoriesChia & Echium Omega-32 mgper 2 Capsule(s)DSLD:5429
- Douglas LaboratoriesEssential Female Pack1 mgper 1 Packet(s)DSLD:232997
- Douglas LaboratoriesEssential Male Pack1 mgper 1 Packet(s)DSLD:286492
- Douglas LaboratoriesEye Moisture Support1.5 mgper 2 Softgel(s)DSLD:232609
- Douglas LaboratoriesJuvenon Pro Longevity2 mgper 3 Vegetarian Capsule(s)DSLD:57726
- Douglas LaboratoriesK2-D3 with Astaxanthinorganic Astaxanthin · supercritical CO2 extract, entire plant2 mgper 1 Vegetarian Capsule(s)DSLD:274066
- Douglas LaboratoriesMetabolic Rejuvenation Week 4 Renew0.5 mgper 1 PackDSLD:261764
- Douglas LaboratoriesNeuroKrillAstaxanthin · Astaxanthin Esters (Form: as Astaxanthin)700 mcgper 1 Caplique(R) Capsule(s)DSLD:57704
- Douglas LaboratoriesPack #1, Joint Health Pack1 mgper 1 Packet(s)DSLD:31413
- Douglas LaboratoriesPack #1, Joint Health Pack1 mgper 1 Packet(s)DSLD:31417
- Douglas LaboratoriesPM Pack0.5 mgper 1 Packet(s)DSLD:230287
- Douglas LaboratoriesQuell Fish Oil EFA Plus1.5 mgper 2 Softgel(s)DSLD:232787
- Douglas LaboratoriesQuell Fish Oil EFA Plus1.5 mgper 2 Softgel(s)DSLD:238721
- Douglas LaboratoriesSkin Probiotic+Haematococcus pluvialis Algae Extract4 mgper 1 Vegetarian Acid-Resistant Capsule(s)DSLD:302507
- Douglas LaboratoriesUltra Preventive 2 Daily1 mgper 2 Tablet(s)DSLD:245412
- Douglas LaboratoriesUltra Preventive 2 Daily1 mgper 2 Tablet(s)DSLD:274165
- Douglas LaboratoriesUltra-Joint Forte1 mgper 3 Tablet(s)DSLD:237106
- Douglas LaboratoriesUltra-Joint Forte1 mgper 3 Tablet(s)DSLD:286739
- Douglas LaboratoriesWeek Four: Renew0.5 mgper 1 Packet(s)DSLD:231039
- Dr. Clark Research Association Dr. Clark ZentrumClark All-in-One6,000 mcgper 20 Gram(s)DSLD:255085
- Dr. Clark StoreVirgin Krill Oil 500 mg80 mcgper 1 Softgel(s)DSLD:220923
- Dr. David WilliamsEyeMEGA Smoothie Tangerine FlavorHaematococcus pluvialis Algae Extract · Astaxanthin (Form: from Haematococcus pluvialis Algae extract Genus: Haematococcus Species: pluvialis)2 mgper 1 TbspDSLD:61954
- Dr. MercolaAntarctic Krill Oil2 mgper 2 Capsule(s)DSLD:287206
- Dr. MercolaAntarctic Krill OilOrganic2 mgper 2 Capsule(s)DSLD:308607
- Dr. MercolaAntarctic Krill Oilorganic2 mgper 2 Capsule(s)DSLD:327098
- Dr. MercolaAntarctic Krill OilOrganic2 mgper 2 Capsule(s)DSLD:327099
- Dr. MercolaAntarctic Krill Oil Double Strengthorganic4 mgper 3 Capsule(s)DSLD:308608
- Dr. MercolaAntarctic Krill Oil Double Strengthorganic4 mgper 3 Capsule(s)DSLD:327100
- Dr. MercolaAntarctic Krill Oil for Womenorganic2 mgper 3 Capsule(s)DSLD:327101
- Dr. MercolaAntarctic Krill Oil for Womenorganic2 mgper 3 Capsule(s)DSLD:327102
- Dr. MercolaAstaxanthin 12 mgHaematococcus pluvialis Extract · organic astaxanthin12 mgper 1 Capsule(s)DSLD:308609
- Dr. MercolaAstaxanthin 12 mgHaematococcus pluvialis Extract · organic astaxanthin12 mgper 1 Capsule(s)DSLD:308610
- Dr. MercolaAstaxanthin 4 mgHaematococcus pluvialis Extract · organic Astaxanthin extract (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)4 mgper 1 Capsule(s)DSLD:214101
- Dr. MercolaAstaxanthin 4 mgHaematococcus pluvialis Extract · organic Astaxanthin extract (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)4 mgper 1 Capsule(s)DSLD:214102
- Dr. MercolaAstaxanthin 4 mgHaematococcus pluvialis Extract · organic astaxanthin4 mgper 1 Capsule(s)DSLD:308611
- Dr. MercolaAstaxanthin 4 mgHaematococcus pluvialis Extract · organic astaxanthin4 mgper 1 Capsule(s)DSLD:308612
- Dr. MercolaEye SupportHaematococcus pluvialis2 mgper 1 Capsule(s)DSLD:250162
- Dr. MercolaJoint FormulaHaematococcus pluvialis Extract2 mgper 1 Tablet(s)DSLD:308713
- Dr. MercolaJoint FormulaHaematococcus pluvialis Extract2 mgper 1 Tablet(s)DSLD:308714
- Dr. MercolaJoint FormulaHaematococcus pluvialis · organic2 mgper 1 Capsule(s)DSLD:339484
- Dr. MercolaKrill Oil for Kids2 mgper 2 Capsule(s)DSLD:287231
- Dr. MercolaVirgin Salmon Oil4 mcgper 3 Softgel(s)DSLD:76214
- Dr. Mercola Premium SupplementsKrill IQAstaxanthin Esters · Astaxanthin (Form: as astaxanthin esters)100 mcgper 4 Licaps(TM) Capsule(s)DSLD:24892
- Dr. Ohhira'sPropolis PlusHaematococcus algae3 mgper 1 Capsule(s)DSLD:36941
- Dr. Ohhira'sPropolis Plus3 mgper 1 Capsule(s)DSLD:36970
- Dr. Rico PerezHair, Skin & NailsHaematococcus pluvialis Extract250 mcgper 2 Capsule(s)DSLD:321058
- Emerald LabsVision Health1,000 mgper 2 Capsule(s)DSLD:302749
- Epic 4 HealthNatural Astaxanthin 12 mgorganic Haematoccous pluvialis · Astaxanthin (Form: from organic Haematoccous pluvialis Genus: Haematoccous Species: pluvialis) (Alt. Name: AstaZine)12 mgper 1 Softgel(s)DSLD:229903
- EquipReal Omegas29 mcgper 1 Softgel(s)DSLD:248433
- Esmond NaturalKrill Oil 720 mg40 mcgper 2 Softgel(s)DSLD:230755
- Esmond NaturalSkin Whitening Capsule6 mgper 2 Capsule(s)DSLD:230831
- Everyday HealthNZ-Eye3 mgper 1 Capsule(s)DSLD:306105
- FarlongAstaxanthin 12 mgHaematococcus pluvialis · AstaBest Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)12 mgper 1 Softgel(s)DSLD:231135
- FarlongHormone Balance for WomenHaematococcus pluvialis · AstaBest Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)1 mgper 1 Capsule(s)DSLD:231170
- ForeverForever VisionMicro Algae · Astaxanthin (Form: from Micro Algae) Note: 2%10 mgper 2 Tablet(s)DSLD:70433
- FortifeyeFortifeye Advanced Retina FormulaAstaxanthin, Powder · Astaxanthin [P2AF]2 mgper 2 Capsule(s)DSLD:263414
- FortifeyeFortifeye Fit Fruit Punch2 mgper 33 Gram(s)DSLD:229426
- Foster RegalAstaxanthin 5 mgHaematococcus pluvialis5 mgper 1 Softgel(s)DSLD:260159
- Fresh NutritionAstaxanthinHaematococcus pluvialis algae · Astaxanthin (Form: from Haematococcus pluvialis algae Genus: Haematococcus Species: pluvialis)5 mgper 3 Softgel Capsule(s)DSLD:241898
- FREZZOROmega-3 Black 196 mg6 mgper 2 Capsule(s)DSLD:320804
- FREZZOROmega-3 Black 320 196 mgNZ6 mgper 2 Capsule(s)DSLD:320805
- FuturebioticsAntarctic Krill Oil 1000 mg with Astaxanthin200 mcgper 2 Soft Gel(s)DSLD:298826
- FuturebioticsAntarctic Krill Oil 1000 mg with Astaxanthin200 mcgper 2 Softgel(s)DSLD:319995
- FuturebioticsAntarctic Krill Oil 1000 mg with Astaxanthin200 mcgper 2 Softgel(s)DSLD:319996
- FuturebioticsAntarctic Krill Oil 1000 mg with Astaxanthin200 mcgper 2 Softgel(s)DSLD:319997
- Garden of LifeGrass Fed Collagen Super Beauty Blueberry Acai FlavorHaematococcus pluvialis10 mgper 1 Scoop(s)DSLD:222908
- Garden of LifeGrass Fed Collagen Super Beauty Blueberry Acai FlavorHaematococcus pluvialis10 mgper 1 Scoop(s)DSLD:274320
- Garden of Life Dr. FormulatedCBD+ Inflammatory Response Liquid DropsHaematococcus pluvialis2 mgper 1 mLDSLD:222844
- Garden of Life MinamiAlgae Omega-3 Orange Flavor1.5 mgper 2 Softgel(s)DSLD:237197
- Garden of Life Minami NutritionVeganDHA1.5 mgper 2 Softgel(s)DSLD:28661
- GNCAstaxanthin 12 mgHaematococcus pluvialis12 mgper 1 Softgel Capsule(s)DSLD:260138
- GNCMultivitaminHaematococcus pluvialis50 mcgper 2 Beige Caplet(s)DSLD:260119
- GNC AMP Advanced Muscle PerformanceMega Men Sport MultivitaminHaematococcus pluvialis50 mcgper 2 Mocha Brown Timed-Release Caplet(s)DSLD:312637
- GNC AMP Advanced Muscle PerformanceMega Men Sport MultivitaminHaematococcus pluvialis50 mcgper 2 Mocha Brown Caplet(s)DSLD:312702
- GNC AMP Advanced Muscle PerformanceMega Men Sport MultivitaminHaematococcus pluvialis50 mcgper 2 Mocha Brown Caplet(s)DSLD:317645
- GNC Beyond RawHardcore Multivitamin50 mcgper 1 Yellow Tablet(s)DSLD:63766
- GNC Mega Men50 Plus50 mcgper 2 Caplet(s)DSLD:27160
- GNC Mega Men50 PlusHaematococcus pluvialis50 mcgper 2 Caplet(s)DSLD:304603
- GNC Mega Men50 PlusHaematococcus pluvialis50 mcgper 2 Caplet(s)DSLD:304604
- GNC Mega Men50 Plus50 mcgper 2 Caplet(s)DSLD:779
- GNC Mega Men50 Plus MultivitaminHaematococcus pluvialis50 mcgper 2 Caplet(s)DSLD:323511
- GNC Mega MenEnergy & MetabolismHaematococcus pluvialis50 mcgper 2 Caplet(s)DSLD:331658
- GNC Mega MenEnergy & Metabolism5 mcgper 2 Caplet(s)DSLD:33192
- GNC Mega MenEnergy & MetabolismHaematococcus pluvialis50 mcgper 2 Caplet(s)DSLD:334077
- GNC Mega MenEnergy & MetabolismHaematococcus pluvialis50 mcgper 2 Caplet(s)DSLD:334078
- GNC Mega MenEnergy & Metabolism50 mcgper 2 Caplet(s)DSLD:781
- GNC Mega MenHeart50 mcgper 3 Caplet(s)DSLD:67350
- GNC Mega MenHeart50 mcgper 3 Caplet(s)DSLD:780
- GNC Mega MenMaximum Nutrition Milk Chocolate50 mcgper 34 Gram(s)DSLD:31063
- GNC Mega MenMaximum Nutrition Vanilla BeanHaematococcus pluvialis50 mcgper 34 Gram(s)DSLD:801
- GNC Mega MenMega Men50 mcgper 2 Caplet(s)DSLD:19423
- GNC Mega MenMega Men50 mcgper 2 Beige Caplet(s)DSLD:27447
- GNC Mega MenMega Men50 mcgper 2 Beige Caplet(s)DSLD:31992
- GNC Mega MenMega Men50 mcgper 2 Beige Caplet(s)DSLD:33535
- GNC Mega MenMega Men50 mcgper 2 Caplet(s)DSLD:3565
- GNC Mega MenMega Men50 mcgper 2 Caplet(s)DSLD:3566
- GNC Mega MenMega Men50 mcgper 2 Caplet(s)DSLD:5877
- GNC Mega MenMega Men50 mcgper 2 Beige Caplet(s)DSLD:68954
- GNC Mega MenMega Men 50 Plus50 mcgper 2 Caplet(s)DSLD:15713
- GNC Mega MenMega Men 50 Plus50 mcgper 2 Beige Caplet(s)DSLD:33620
- GNC Mega MenMega Men 50 Plus MultivitaminHaematococcus pluvialis50 mcgper 2 Beige Caplet(s)DSLD:259831
- GNC Mega MenMega Men Energy & Metabolism50 mcgper 2 Beige Caplet(s)DSLD:27458
- GNC Mega MenMega Men Energy & Metabolism50 mcgper 2 Beige Caplet(s)DSLD:33660
- GNC Mega MenMega Men MultivitaminHaematococcus pluvialis50 mcgper 2 Beige Caplet(s)DSLD:315852
- GNC Mega MenMega Men MultivitaminHaematococcus pluvialis50 mcgper 2 Beige Caplet(s)DSLD:315091
- GNC Mega MenMega Men MultivitaminHaematococcus pluvialis50 mcgper 2 Beige Caplet(s)DSLD:315818
- GNC Mega MenMega Men MultivitaminHaematococcus pluvialis50 mcgper 2 Beige Caplet(s)DSLD:315844
- GNC Mega MenMega Men Multivitamin50 mcgper 2 Beige Caplet(s)DSLD:33588
- GNC Mega MenMega Men Sport50 mcgper 2 Brown Caplet(s)DSLD:25592
- GNC Mega MenMega Men Sport50 mcgper 2 Caplet(s)DSLD:5872
- GNC Mega MenMega Men Sport50 mcgper 2 Caplet(s)DSLD:5885
- GNC Mega MenProstate & VirilityHaematococcus pluvialis50 mcgper 2 Caplet(s)DSLD:315845
- GNC Mega MenSport50 mcgper 2 Caplet(s)DSLD:778
- GNC Mega MenSport Milk Chocolate50 mcgper 36 Gram(s)DSLD:1060
- GNC Mega MenSport MultivitaminHaematococcus pluvialis50 mcgper 2 Caplet(s)DSLD:334082
- GNC Mega MenSport MultivitaminHaematococcus pluvialis50 mcgper 2 Caplet(s)DSLD:334083
- GNC Mega MenSport One Daily50 mcgper 1 Caplet(s)DSLD:82391
- GNC Mega MenSport Vanilla Bean50 mcgper 36 Gram(s)DSLD:1061
- GNC Men'sMega Men Sport50 mcgper 2 Brown Caplet(s)DSLD:191080
- GNC Preventive NutritionAstaxanthin 4 mg4 mgper 1 Softgel(s)DSLD:7091
- GNC Pro Performance AMPMega Men Sport (Full Strength)50 mcgper 2 Brown Caplet(s)DSLD:42326
- GNC Pro Performance AMPMega Men Sport (Full Strength)50 mcgper 2 Brown Caplet(s)DSLD:45101
- GNC Pro Performance AMPMega Men Sport (Full Strength)50 mcgper 2 Caplet(s)DSLD:5818
- GNC Pro Performance AMPMega Men Sport Full Strength50 mcgper 2 Caplet(s)DSLD:45107
- GNC Pro Performance AMP Advanced Muscle PerformanceMega Men Sport (Full Strength)50 mcgper 2 Caplet(s)DSLD:5772
- GNC Total LeanMultivitamin50 mcgper 2 Pearlescent Beige Tablet(s)DSLD:36323
- GNC Women'sMultivitamin 50 PlusHaematococcus pluvialis50 mcgper 2 Caplet(s)DSLD:331481
- GNC Women'sMultivitamin ActiveHaematococcus pluvialis50 mcgper 2 Caplet(s)DSLD:331482
- GNC Women'sMultivitamin ActiveHaematococcus pluvialis50 mcgper 2 Caplet(s)DSLD:331483
- GNC Women'sMultivitamin Active without IronHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)50 mcgper 2 Caplet(s)DSLD:228961
- GNC Women'sMultivitamin Energy & MetabolismHaematococcus pluvialis50 mcgper 2 Caplet(s)DSLD:331484
- GNC Women'sMultivitamin Energy & MetabolismHaematococcus pluvialis50 mcgper 2 Caplet(s)DSLD:331485
- GNC Women'sMultivitamin Ultra Mega without IronHaematoccous pluvialis · Astaxanthin (Form: from Haematoccous pluvialis Genus: Haematoccous Species: pluvialis)50 mcgper 2 Caplet(s)DSLD:243740
- GNC Women'sMultivitamin Ultra Mega Without IronHaematoccous pluvialis · Astaxanthin (Form: from Haematoccous pluvialis Genus: Haematoccous Species: pluvialis)50 mcgper 2 Caplet(s)DSLD:229043
- GNC Women'sUltra Mega MultivitaminHaematococcus pluvialis50 mcgper 2 Caplet(s)DSLD:315330
- GNC Women'sWomen's Bone Density without Iron and Iodine Multivitamin50 mcgper 4 Pink Caplet(s)DSLD:243696
- GNC Women'sWomen's Ultra Mega 50 Plus50 mcgper 2 Caplet(s)DSLD:3234
- GNC Women'sWomen's Ultra Mega Multivitamin without IronHaematococcus pluvialis50 mcgper 2 Light Green Caplet(s)DSLD:315336
- GNC Women'sWomen's Ultra Mega without IronHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)50 mcgper 2 Light Green Caplet(s)DSLD:243670
- GNC Women's Ultra MegaActive50 mcgper 2 Caplet(s)DSLD:788
- GNC Women's Ultra MegaActive Milk Chocolate50 mcgper 35 Gram(s)DSLD:1062
- GNC Women's Ultra MegaActive Vanilla Creme50 mcgper 35 Gram(s)DSLD:1063
- GNC Women's Ultra MegaBone Density50 mcgper 4 Caplet(s)DSLD:74790
- GNC Women's Ultra MegaBone Density Without Iron And Iodine50 mcgper 4 Caplet(s)DSLD:74818
- GNC Women's Ultra MegaEnergy & Metabolism50 mcgper 2 Caplet(s)DSLD:33250
- GNC Women's Ultra MegaEnergy And Metabolism50 mcgper 2 Caplet(s)DSLD:12031
- GNC Women's Ultra MegaEnergy And Metabolism50 mcgper 2 Caplet(s)DSLD:798
- GNC Women's Ultra MegaHeart50 mcgper 3 Caplet(s)DSLD:70131
- GNC Women's Ultra MegaMaximum Nutrition Milk ChocolateHaematococcus pluvialis50 mcgper 34 Gram(s)DSLD:27807
- GNC Women's Ultra MegaMaximum Nutrition Vanilla CremeHaematococcus pluvialis50 mcgper 34 Gram(s)DSLD:802
- GNC Women's Ultra MegaWomen's Ultra Mega 50 Plus50 mcgper 2 Green Caplet(s)DSLD:33501
- GNC Women's Ultra MegaWomen's Ultra Mega Active Without Iron50 mcgper 2 Orange Caplet(s)DSLD:42238
- GNC Women's Ultra MegaWomen's Ultra Mega Active Without Iron50 mcgper 2 Orange Caplet(s)DSLD:65939
- GNC Women's Ultra MegaWomen's Ultra Mega Bone Density Without Iron & Iodine50 mcgper 4 Pink Caplet(s)DSLD:75186
- GNC Women's Ultra MegaWomen's Ultra Mega Multivitamin without IronHaematococcus pluvialis50 mcgper 2 Caplet(s)DSLD:259954
- GNC Women's Ultra MegaWomen's Ultra Mega With Probiotics50 mcgper 4 Capsule(s)DSLD:1658
- GNC Women's Ultra MegaWomen's Ultra Mega With Probiotics50 mcgper 4 Capsule(s)DSLD:27806
- GNC Women's Ultra MegaWomen's Ultra Mega Without Iron & Iodine50 mcgper 2 Caplet(s)DSLD:15697
- GNC Women's Ultra MegaWomen's Ultra Mega Without Iron And Iodine50 mcgper 2 Tablet(s)DSLD:19458
- GNC Women's Ultra MegaWomen's Ultra Mega Without Iron And Iodine50 mcgper 2 Light Green Caplet(s)DSLD:42259
- GNC Women's Ultra MegaWomen's Ultra Mega Without Iron And Iodine50 mcgper 2 Caplet(s)DSLD:5881
- GNC Women's Ultra MegaWomen's Ultra Mega Without Iron And Iodine50 mcgper 2 Light Green Caplet(s)DSLD:83083
- Greens FirstGreens First Berry0.4 mgper 9.6 Gram(s)DSLD:312843
- Greens FirstGreens First Berry1%1 mgper 9.6 Gram(s)DSLD:317865
- H!D Hallelujah DietJoint HealthAstaxanthin · std. min. 2.5%2 mgper 4 Capsule(s)DSLD:268073
- HD MuscleVitaHD Essential Health Multi500 mcgper 5 Capsule(s)DSLD:245711
- Health From The SunKrill OilAstaxanthin Note: esterified1.5 mgper 2 Softgel(s)DSLD:34216
- Health PlusBlood Cleanse100 mcgper 2 Capsule(s)DSLD:255758
- Health PlusKidney Cleanse536 mcgper 2 Capsule(s)DSLD:271669
- Health PlusSuper Adrenal Cleanse500 mcgper 2 Capsule(s)DSLD:228867
- Health PlusSuper Heart Cleanse280 mcgper 3 Capsule(s)DSLD:47107
- Health PlusSuper Joint Cleanse500 mcgper 4 Capsule(s)DSLD:47110
- Health PlusSuper Kidney Cleanse500 mcgper 2 Capsule(s)DSLD:47082
- Health PlusSuper Liver Cleanse500 mgper 1 Capsule(s)DSLD:47081
- Health PlusSuper Prostate Cleanse365 mcgper 2 Capsule(s)DSLD:47113
- Health Ranger'sHawaiian AstaxanthinHaematococcus pluvialis microalgae12 mgper 1 Gel Cap(s)DSLD:257621
- Health Thru NutritionAstaxanthan 12 mgorganic Haematococcus pluvialis12 mgper 1 Softgel(s)DSLD:304822
- Health Thru NutritionAstaxanthin 12 mgorganic Haematococcus pluvialis12 mgper 1 Softgel(s)DSLD:304821
- Health Thru NutritionFreedom SoftgelsAstaxanthin, Natural6 mgper 2 Softgel(s)DSLD:304838
- HealtHeavenNature PowerAlgae0.25 mgper 2 Capsule(s)DSLD:293094
- Healthy DirectionsAstaxanthin 6 mgHaematococcus pluvialis Algae extract · Astaxanthin (Form: from Haematococcus pluvialis Algae extract Genus: Haematococcus Species: pluvialis) (Alt. Name: AstaReal)6 mgper 1 Softgel(s)DSLD:230552
- Healthy DirectionsAstaxanthin 6 mgHaematococcus pluvialis Algae extract6 mgper 1 Softgel(s)DSLD:267458
- Healthy OriginsAstaxanthin 4 mgAstaPure12 mgper 1 Softgel(s)DSLD:269188
- Healthy OriginsTriple Strength Astaxanthin 12 mgAstaPure12 mgper 1 Softgel(s)DSLD:269189
- Healthy OriginsTriple Strength Astaxanthin 12 mgAstaxanthin12 mgper 1 Softgel(s)DSLD:305574
- HerbadietAntioxidant ComplexStandardized to contain min. 10% Astaxanthin50 mgper 1 Capsule(s)DSLD:257343
- HerbadietAntioxidant Complex with Beta Caroltene, Lutein, Zeaxanthin, Lycopene & Astaxanthinastaxanthin extract powder, standardized to contain min. 10% astaxanthin50 mgper 1 Capsule(s)DSLD:293683
- HerbadietAntioxidant Complex with Beta Carotene, Lutein, Zeaxanthin, Lycopene & Astaxanthin PowderAstaxanthin · Notes: Standardized to contain min. 10% Astaxanthin50 mgper 325 mgDSLD:293723
- HerbadietAstaxanthinAstaxanthin · Standardized to contain min. 10% Astaxanthin100 mgper 1 Capsule(s)DSLD:257380
- HerbadietAstaxanthin ExtractHaematococcus pluvialis Extract, Powder · Standardized to contain min. 10% astaxanthin100 mgper 1 Capsule(s)DSLD:293760
- HerbadietAstaxanthin Extract PowderAstaxanthin · Stardardized to contain min. 10% Astaxanthin100 mgper 100 mgDSLD:293524
- HerbadietImmune ShieldHaematococcus pluvialis · standardized to contain min. 10% astaxanthin20 mgper 1 Capsule(s)DSLD:257698
- Herbal NutritionOcuShieldHaematococcus pluvialis Algae Extract · CO2 Extract6 mgper 1 Softgel(s)DSLD:317384
- Higher NatureAstaxanthinHaematococcus pluvialis4 mgper 1 Capsule(s)DSLD:275896
- Higher NatureAstaxanthin & Black CurrantHaematococcus pluvialis · pure Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)4 mgper 2 Capsule(s)DSLD:223332
- Higher NatureAstaxanthin & Black CurrantHaematococcus pluvialis4 mgper 2 Capsule(s)DSLD:304531
- Higher NatureAstaxanthin & Black CurrantHaematococcus pluvialis · pure Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)4 mgper 2 Capsule(s)DSLD:42208
- Higher NatureDLPA ComplexHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)1 mgper 1 Capsule(s)DSLD:216986
- Higher NatureDLPA ComplexHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)1 mgper 1 Capsule(s)DSLD:41266
- Higher NatureSuperPhyteHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)0.5 mgper 1 Capsule(s)DSLD:217181
- Higher NatureSuperPhyteHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)0.5 mgper 1 Capsule(s)DSLD:245874
- Higher NatureSuperPhyte0.5 mgper 1 Capsule(s)DSLD:304555
- Higher Nature Aeterna GoldAstaxanthin CapsulesHaematococcus pluvialis · AstaPure Pure Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)4 mgper 1 Capsule(s)DSLD:223308
- HUMANXProMacular4 mgper 1 Capsule(s)DSLD:284109
- IheerboCO Q10 200 mg with Astaxanthin5 mgper 1 Softgel(s)DSLD:336801
- Indiana Botanic GardensRed Krill Oil 1000 mg200 mgper 1 Softgel(s)DSLD:27731
- InfoWars LifeOccu Power30 mcgper 1 Capsule(s)DSLD:78303
- Innate Response FormulasOne Daily Cap25 mcgper 1 Capsule(s)DSLD:177868
- Inspire HealthAstaxanthin 4 mg4 mgper 1 Capsule(s)DSLD:215651
- InViteMultivitamin Liquid Vegetarian Capsule750 mcgper 1 Liquid Vegetarian Capsule(s)DSLD:328202
- Irwin NaturalsCollagen Peptides + AstaxanathinAstaxanthin · fermented4 mgper 4 Liquid Soft-Gel(s)DSLD:323279
- IVLAstaxanthin 12 mgHaematococcus pluvialis Extract12 mgper 1 Softgel(s)DSLD:277914
- IVLVision Clear Bcontains 2% astaxanthin4 mgper 2 Vegetable Capsule(s)DSLD:278401
- IVL Institute For Vibrant LivingBrain Booster8 mgper 2 Softgel(s)DSLD:15376
- IVL Institute For Vibrant LivingOmega Max Gold Lemon FlavorHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)100 mcgper 2 Softgel(s)DSLD:60821
- Jarrow FormulasAstaxanthin 12 mgHaematococcus pluvialis12 mgper 1 Softgel(s)DSLD:307556
- Jarrow FormulasAstaxanthin 12 mgHaematococcus pluvialis12 mgper 1 Softgel(s)DSLD:321949
- Jarrow FormulasCarotenAllHaematococcus pluvialis500 mcgper 1 Softgel(s)DSLD:307570
- Jarrow FormulasMaculaPFHaematococcus pluvialis4 mgper 1 Softgel(s)DSLD:307645
- Jarrow FormulasMaculaPFHaematococcus pluvialis4 mgper 1 Softgel(s)DSLD:321955
- JayLab ProOmega Icon86 mcgper 2 Softgel(s)DSLD:218370
- Jocko FuelJocko Super Krill200 mcgper 2 Softgel(s)DSLD:232545
- Juice Plus+Fruit Blend +amount not statedper 2 Capsule(s)DSLD:245488
- Juice Plus+Vegetable Blend +amount not statedper 2 Capsule(s)DSLD:245480
- Kala HealthAnti-Oxidant ComplexAstaxanthin4 mgper 1 Capsule(s)DSLD:311291
- Kala HealthAstaxanthinAstaxanthin4 mgper 1 Capsule(s)DSLD:311292
- Kala HealthKrill Oil190 mcgper 1 Capsule(s)DSLD:311299
- Kala HealthKrill Oil190 mcgper 1 Capsule(s)DSLD:311300
- Kirkland SignatureKrill Oil 500 mg150 mcgper 1 Softgel(s)DSLD:207339
- Klean AthleteKlean Antioxidant2 mgper 3 Vegetarian Capsule(s)DSLD:237072
- Klean AthleteKlean Joint & MuscleAstaxanthin4 mgper 2 Vegetarian Capsule(s)DSLD:259897
- Klean AthleteKlean Multivitamin1 mgper 2 Tablet(s)DSLD:232699
- Klean AthleteKlean Multivitamin1 mgper 2 Tablet(s)DSLD:276544
- Krill Doctor ProfessionalKrill Omega-3300 mcgper 2 Softgel(s)DSLD:175022
- LABO NutritionCardioRegainAstaxanthin4 mgper 1 Softgel(s)DSLD:295369
- LAIFEAnti-Aging ProHaematococcus pluvialis4 mgper 3 Vegetarian Capsule(s)DSLD:301424
- Lake Avenue NutritionAstaxanthin 10 mgHaematococcus pluvialis Extract10 mgper 1 Softgel(s)DSLD:274387
- Lake Avenue NutritionAstaxanthin 10 mgHaematococcus pluvialis Extract10 mgper 1 Softgel(s)DSLD:299320
- Levins PharmaTobakientHaematococcus pluvialis Algae extract · Astaxanthin (Form: from Haematococcus pluvialis Algae extract Genus: Haematococcus Species: pluvialis) (Alt. Name: AstaReal)4 mgper 1 Capsule(s)DSLD:263582
- LifeBright EyesAstaREAL Algae2 mgper 1 Softgel(s)DSLD:46180
- LifeBright Eyes with Bilberry & LuteinAstaREAL Algae2 mgper 1 Softgel(s)DSLD:76745
- Life ExtensionMacuGuardHaematococcus pluvialis algae · natural Astaxanthin (Form: from CO2 extracts of Haematococcus pluvialis algae Genus: Haematococcus Species: pluvialis)6 mgper 1 Softgel(s)DSLD:59729
- Life ExtensionMacuGuardHaematococcus pluvialis algae · natural Astaxanthin (Form: from CO2 extract of Haematococcus pluvialis algae Genus: Haematococcus Species: pluvialis)6 mgper 1 Softgel(s)DSLD:60783
- Life ExtensionMacuGuard Ocular Support with Saffron & AstaxanthinHaematococcus pluvialis algae · natural Astaxanthin (Form: from CO2 extract of Haematococcus pluvialis algae Genus: Haematococcus Species: pluvialis)6 mgper 1 Softgel(s)DSLD:182388
- Life ExtensionMacuGuard Ocular Support with Saffron & AstaxanthinHaematococcus pluvialis algae · natural Astaxanthin (Form: from CO2 extract of Haematococcus pluvialis algae Genus: Haematococcus Species: pluvialis)6 mgper 1 Softgel(s)DSLD:232205
- Life ExtensionMacuGuard Ocular Support with Saffron & AstaxanthinHaematococcus pluvialis algae · natural Astaxanthin (Form: from CO2 extract of Haematococcus pluvialis algae Genus: Haematococcus Species: pluvialis)6 mgper 1 Softgel(s)DSLD:232206
- Life ExtensionSuper Omega With Krill, Astaxanthin & Olive Fruit ExtractHaematococcus pluvialis algae · natural Astaxanthin (Form: from CO2 extract of Haematococcus pluvialis algae Genus: Haematococcus Species: pluvialis)2 mgper 2 Softgel(s)DSLD:60701
- Life ExtensionSuper Omega-3 PlusHaematococcus pluvialis algae · natural Astaxanthin (Form: from CO2 extract of Haematococcus pluvialis algae Genus: Haematococcus Species: pluvialis)2 mgper 2 Softgel(s)DSLD:232624
- LifeSeasonsHealthy Aging Antioxidant Complex100 mcgper 3 Capsule(s)DSLD:276058
- LifeSeasons TherapeuticsAgeless Skin Care100 mcgper 3 Capsule(s)DSLD:310456
- Live ConsciousKrillWell600 mcgper 3 Softgel(s)DSLD:316084
- Living FuelSuper Essentials Omegas 3EDA+Algae · Astaxanthin (Form: from Algae (Form: Haematococcus pluvialis Genus: Haematococcus Species: pluvialis))1 mgper 1 Softgel(s)DSLD:282561
- LuckyVitaminAstaxanthin 4 mgHaematococcus pluvialis Algae Extract4 mgper 1 Softgel(s)DSLD:283102
- LuckyVitaminNeptune Krill Oil 500 mg360 mgper 2 Softgel(s)DSLD:283249
- LuckyVitaminSuper Krill 1,000 mg360 mcgper 1 Softgel(s)DSLD:283303
- Market AmericaUltimate AloeAstaxanthin2 mgper 5 Gram(s)DSLD:313425
- Market AmericaUltimate Aloe Natural Flavored PowderAstaxanthin2 mgper 5 Gram(s)DSLD:298833
- Maxi HealthVision to the Max4 mgper 2 Maxicap(s)DSLD:323815
- MedOpMaxiVision Ocular Formula500 mcgper 2 Vegetable Capsule(s)DSLD:27736
- MeijerAstaxanthin 5 mgHaematococcus pluvialis Algae Extract5 mgper 1 Softgel(s)DSLD:271709
- Member's Mark100 % Pure Omega-3 Krill Oil 500 mg150 mcgper 1 Softgel(s)DSLD:239930
- Member's Mark100% Pure Omega-3 Krill Oil 350 mg95 mcgper 1 Softgel(s)DSLD:239940
- Member's MarkExtra Strength 100% Pure Omega-3 Krill Oil 500 mg150 mcgper 1 Softgel(s)DSLD:240065
- MenoLabsMenofitAlgae · Astaxanthin Complex Note: Algae derived15 mgper 2 Capsule(s)DSLD:271145
- Mental RefreshmentKrill Oil 1000 mg1,500 mcgper 2 Capsule(s)DSLD:247641
- MetagenicsEndefen250 mcgper 7.5 Gram(s)DSLD:323351
- Micro IngredientsAstaxanthin 15 mgHaematococcus pluvialis microalgae15 mgper 15 mgDSLD:256749
- Micro IngredientsKrill Oil400 mcgper 2 Softgel(s)DSLD:256799
- Micro IngredientsPure Krill Oil400 mcgper 2 Softgel(s)DSLD:231701
- MM Sports NutritionMax Multi Men's50 mcgper 2 Capsule(s)DSLD:37141
- MN Morphogen NutritionMorphodermAlgae8 mgper 6 Capsule(s)DSLD:261161
- Moon JuiceSuperBeautyAstazine · Astaxanthin (Form: as Astazine (Form: organic Haematococcus pluvialis microalgae Genus: Haematococcus Species: pluvialis))4 mgper 2 Vegetarian Capsule(s)DSLD:220571
- Mountain Meadow HerbsKrill Oil 1000 mg400 mcgper 1 Softgel(s)DSLD:327798
- Mountain Meadow HerbsKrill Oil 1200 mg1 mcgper 1 Softgel(s)DSLD:267493
- MRMFresh Omega Extra Virgin Norwegian Salmon Oil6 mcgper 1 Fish softgel(s)DSLD:178447
- MYOGENIX Sports NutritionMyomega8 mgper 3 Softgel(s)DSLD:47830
- MyTritionBiotin Advanced6 mgper 1 Tablet(s)DSLD:180794
- MyTritionMen's High-Potency Multivitamin50 mcgper 2 Tablet(s)DSLD:80740
- MyTritionMen's High-Potency Multivitamin50 mcgper 2 Tablet(s)DSLD:81313
- MyTritionWomen's High-Potency Multivitamin50 mcgper 2 Tablet(s)DSLD:81358
- MyTritionWomen's High-Potency Multivitamin50 mcgper 2 Tablet(s)DSLD:80730
- MyTritionWomen's High-Potency Multivitamin50 mcgper 2 Tablet(s)DSLD:81721
- NasaBe'AhavaAstaxanthin 10mgHaematococcus pluvialis10 mgper 1 Softgel(s)DSLD:321992
- Native RemediesNR Essentials Multivitamin For Women500 mcgper 3 Capsule(s)DSLD:13805
- NativePathAntarctic Krill Oil200 mcgper 1 Softgel(s)DSLD:275986
- Natural FactorsAstaxanthin Plus 4 mgHaematococcus pluvialis4 mgper 1 Softgel(s)DSLD:74714
- Natural FactorsComplete Omega 100% Wild Alaskan Salmon Oil 1300 mgwild Alaskan Salmon Oil · Astaxanthin (Form: wild Alaskan Salmon Oil) Note: naturally occurring26.7 mcgper 1 Softgel(s)DSLD:75502
- Natural FactorsComplete Omega 100% Wild Alaskan Salmon Oil 1300 mgwild Alaskan Salmon Oil · Astaxanthin (Form: wild Alaskan Salmon Oil) Note: naturally occurring26.7 mcgper 1 Softgel(s)DSLD:75504
- Natural Factors CurcuminRichWhole Body CurcumizerHaematococcus pluvialis2 mgper 1 Softgel(s)DSLD:180139
- Natural Factors Whole Earth & SeaCogni-FitHaematococcus pluvialis · Astaxanthin (Form: Haematococcus pluvialis PlantPart: whole Genus: Haematococcus Species: pluvialis) Note: natural360 mcgper 1 Softgel(s)DSLD:46665
- Natural NutraKrill Oil425 mcgper 1 Softgel(s)DSLD:246973
- Nature MadeAstaxanthin 4 mgHaematococcus pluvialis algae · Astaxanthin (Form: from Haematococcus pluvialis algae Genus: Haematococcus Species: pluvialis)4 mgper 1 Softgel(s)DSLD:179791
- Nature MadeKrill Oil 300 mg120 mcgper 2 Softgel(s)DSLD:179775
- Nature's BountyAstaxanthin 5 mgHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)5 mgper 1 Softgel(s)DSLD:4229
- Nature's LabAstaxanthin 12 mgHaematococcus pluvialis algae extract · AstaReal Astaxanthin (Form: from Haematococcus pluvialis algae extract Genus: Haematococcus Species: pluvialis)12 mgper 1 Softgel(s)DSLD:205289
- Nature's LabAstaxanthin 12 mgHaematococcus pluvialis algae extract · AstaReal Astaxanthin (Form: from Haematococcus pluvialis algae extract Genus: Haematococcus Species: pluvialis)12 mgper 1 Softgel(s)DSLD:205355
- Nature's LabAstaxanthin 6 mgAstaxanthin, Natural6 mgper 1 Softgel(s)DSLD:334712
- Nature's VisionNatural Double Strength AstaxanthinHaematoccus pluvialis, Natural8 mgper 2 Tablet(s)DSLD:276206
- Nature's WayEfaGold Krill Oil 500 mg80 mcgper 1 Softgel(s)DSLD:201245
- NatureCityTrueAstaAstaxanthin, Natural6 mgper 1 Softgel(s)DSLD:283366
- NatureCityTrueCircAstaxanthin, Natural6 mgper 1 Softgel(s)DSLD:283374
- Natures Plus BrainCeutixOmega+Haematoccous pluvialis · Astaxanthin (Form: from Haematoccous pluvialis Genus: Haematoccous Species: pluvialis)3 mgper 2 Softgel(s)DSLD:188885
- NaturesPlusOmega Krill Oil 600 mgKrill3 mgper 1 Liquid-Filled Capsule(s)DSLD:298566
- NaturesPlus AgeLossEye SupportHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)250 mcgper 2 Capsule(s)DSLD:250341
- NaturesPlus BrainCeutixBoostHaematoccous pluvialis · Astaxanthin (Form: from Haematoccous pluvialis Genus: Haematoccous Species: pluvialis)300 mcgper 3 Capsule(s)DSLD:249534
- NDXKrill Oil DX1.5 mgper 2 Softgel(s)DSLD:282447
- New ChapterWholeMega Extra-Virgin Wild Alaskan Salmon Whole Fish Oilwild Alaskan Salmon Oil · Astaxanthin (Form: from Wild Alaskan Salmon Oil)5 mcgper 1 Softgel(s)DSLD:12268
- New ChapterWholemega Fish Oil for Momswild Alaskan Salmon Oil2.5 mcgper 4 Softgel(s)DSLD:288226
- New VitalityRuby Reds15 mgper 10.31 Gram(s)DSLD:277274
- New VitalityRuby Reds1 mgper 10.28 Gram(s)DSLD:82404
- NewtonEverettAstaxanthin 4 mg4 mgper 1 Softgel(s)DSLD:248896
- NewtonEverettOcuVisi Advanced1 mgper 4 Vegetarian Capsule(s)DSLD:248817
- Nootropics DepotAlaskrill Fish Oil Softgels 500 mg50 mcgper 1 Softgel(s)DSLD:231946
- Nootropics DepotNKO Krill Oil Softgels 500 mg360 mcgper 1 Softgel(s)DSLD:251138
- Nootropics DepotNKO Neptune Krill Oil Softgels360 mcgper 1 Softgel(s)DSLD:232419
- North American Herb & SpicePolarPower240 mcgper 2 Softgel(s)DSLD:269987
- North American Herb & SpicePolarPower120 mcgper 1 Teaspoon(s)DSLD:269989
- NOWAstaxanthin 4 mgorganic Haematococcus pluvialis · Astaxanthin (Form: from organic Haematococcus pluvialis microalgae Genus: Haematococcus Species: pluvialis) (Alt. Name: AstaZine)4 mgper 1 Veg Capsule(s)DSLD:205705
- NOWAstaxanthin 4 mgAstaxanthin4 mgper 1 Veggie Softgel(s)DSLD:307920
- NOWAstaxanthin 4 mgAstaxanthin4 mgper 1 Softgel(s)DSLD:313567
- NOWExtra Strength Astaxanthin 10 mgAstaxanthin10 mgper 1 Softgel(s)DSLD:303911
- NOWExtra Strength Astaxanthin 10 mgAstaxanthin10 mgper 1 Softgel(s)DSLD:314310
- NOWKrill Oil 500 mg360 mcgper 2 Softgel(s)DSLD:313875
- NOWKrill Oil 500 mgesterified360 mcgper 2 Softgel(s)DSLD:335260
- NOWTriple Strength Astaxanthin 12 mgAstaxanthin12 mgper 1 Veggie Softgel(s)DSLD:303934
- NOW SolutionsAquatic BeautyAstaxanthin3 mgper 3.2 Gram(s)DSLD:314231
- NS Natural StacksHigh DHA Krill Oil300 mgper 2 Softgel(s)DSLD:66722
- NS Natural StacksMax DHA Krill Oil300 mgper 2 Softgel(s)DSLD:274237
- NutraMedixAntarctic Krill Oil43 mcgper 1 Softgel(s)DSLD:297340
- Nutrex HawaiiBioAstin 4 mg Hawaiian AstaxanthinHaematococcus pluvialis microalgae · natural Hawaiian Astaxanthin (Form: from Haematococcus pluvialis microalgae Genus: Haematococcus Species: pluvialis)1 mgper 1 Gel Cap(s)DSLD:57995
- Nutrex HawaiiBioAstin Hawaiian Astaxanthin 12 mgHaematococcus pluvialis microalgae · natural Hawaiian Astaxanthin (Form: from Haematococcus pluvialis microalgae Genus: Haematococcus Species: pluvialis)12 mgper 1 Gel Cap(s)DSLD:58188
- Nutrex HawaiiBioAstin Hawaiian Astaxanthin 4 mgHaematococcus pluvialis microalgae · natural Hawaiian Astaxanthin (Form: from Haematococcus pluvialis microalgae Genus: Haematococcus Species: pluvialis)12 mgper 1 Gel Cap(s)DSLD:58176
- NutriCologyAstaxanthin 6 mg6 mgper 1 Softgel(s)DSLD:234768
- NutricostAstaxanthin 12 mgHaematococcus pluvialis · natural Astaxanthin (Form: from Haematococcus pluvialis PlantPart: microalgae Genus: Haematococcus Species: pluvialis)12 mgper 1 Softgel(s)DSLD:221690
- NutricostAstaxanthin 12 mgHaematococcus pluvialis · natural Astaxanthin (Form: from Haematococcus pluvialis PlantPart: microalgae Genus: Haematococcus Species: pluvialis)12 mgper 1 Softgel(s)DSLD:222695
- NutricostAstaxanthin 12 mgHaematoccocus pluvialis microalgae12 mgper 1 Softgel(s)DSLD:269279
- NutricostAstaxanthin 12 mgHaematococcus pluvialis12 mgper 1 Softgel(s)DSLD:306060
- NutricostAstaxanthin 12 mgHaematococcus pluvialis12 mgper 1 Softgel(s)DSLD:306061
- NutriGoldAstaxanthin Gold 4 mgAstaxanthin · solvent-free4 mgper 1 Softgel(s)DSLD:309137
- NutriGoldAstaxanthin Gold 4 mgAstaxanthin · solvent-free4 mgper 1 Softgel(s)DSLD:309902
- NutriSuppzSuper Krill Oil Complex 500 mg200 mcgper 1 Softgel(s)DSLD:268894
- OL Olympian LabsKrill Oil 1000 mg1.5 mgper 2 Softgel(s)DSLD:326661
- OL Olympian LabsKrill Oil 1000 mg1.5 mgper 2 Softgel(s)DSLD:326672
- OL Olympian LabsKrill Oil 500 mg750 mcgper 1 Softgel(s)DSLD:175745
- OL Olympian LabsRekover8 mgper 2 Softgel(s)DSLD:53142
- OL Olympian LabsUltimate Krill Complex8 mgper 2 Softgel(s)DSLD:176045
- OnnitDay Pack: Krill Oil60 mcgper 1 Softgel(s)DSLD:67387
- OnnitKrill Oil100 mcgper 1 Softgel(s)DSLD:273144
- OnnitKrill Oil100 mcgper 1 Softgel(s)DSLD:273176
- OnnitKrill Oil200 mcgper 2 Softgel(s)DSLD:295149
- OnnitNight Pack: Krill Oil60 mcgper 1 Softgel(s)DSLD:67393
- OptiChoiceUltimate OmegaChoicePlus600 mcgper 2 Softgel(s)DSLD:217041
- OrganifiMove6 mgper 2 Softgel(s)DSLD:247555
- P2LifeAnti-Oxidant1 mgper 1 Capsule(s)DSLD:19130
- P2LifeSport Multi-Vitamin for Men60 mcgper 3 Capsule(s)DSLD:182804
- Pathway To HealingVision Supportmicroalgae Haematococcus pluvialis · Astaxanthin (Form: from microalgae Haematococcus pluvialis)5 mgper 2 Capsule(s)DSLD:5905
- Performance LabVisionHaematococcus pluvialis Algae Extract · algal4 mgper 1 NutriCap(s)DSLD:331706
- PharmaxFinest Pure Krill OilEsterized Astaxanthin · Esterized Astaxanthin (Form: Other Omega-3's Phospholipids, Esterized Astaxanthin, provided as Krill Oil)750 mcgper 2 Capsule(s)DSLD:55436
- Physician's SignatureTru-Sorb Megacor600 mcgper 2 Softgel Capsule(s)DSLD:272421
- Physician's StrengthPolarVite240 mcgper 2 Softgel(s)DSLD:268770
- Physician's StrengthPolarVite120 mcgper 1 Teaspoon(s)DSLD:268921
- plntWhole Food Men's 50+ Multivitamin2 mgper 2 Vegetarian Capsule(s)DSLD:221428
- plntWhole Food Men's 50+ Multivitamin2 mgper 2 Vegetarian Capsule(s)DSLD:221443
- plntWhole Food Women's 50+ Multivitamin2 mgper 2 Vegetarian Capsule(s)DSLD:221448
- plntWhole Food Women's 50+ Multivitamin2 mgper 2 Vegetarian Capsule(s)DSLD:221455
- PowerLife by Tony HortonEnduranceHawaiian Astaxanthin6 mgper 1 Capsule(s)DSLD:323746
- Premier Research LabsAsta Complete-FXHaematococcus pluvialis17 mgper 2 Capsule(s)DSLD:297513
- Primal ForceDr. Sears' Private Label Primal Force Ultra Omeganol2.5 mgper 1 Softgel(s)DSLD:206523
- Primal HarvestPrimal Flex2 mgper 2 Capsule(s)DSLD:277124
- PrimeAstaxanthinAstaxanthin6 mgper 1 Softgel(s)DSLD:298810
- ProCapsAstaxanthin 4000Haematococcus pluvialis oil · Astaxanthin (Form: from Haematococcus pluvialis oil Genus: Haematococcus Species: pluvialis) Note: 4 mg4,000 mcgper 1 Softgel(s)DSLD:248392
- ProCapsUltimate Eye Support4000 mcg4 mgper 2 Capsule(s)DSLD:331607
- ProCaps LaboratoriesAstaxanthinHaematococcus pluvialis oil · Astaxanthin (Form: from Haematococcus pluvialis oil Genus: Haematococcus Species: pluvialis) Note: 4 mg4,000 mcgper 1 Softgel(s)DSLD:69490
- ProCaps LaboratoriesAstaxanthin 12 12,000 mcgHaematococcus pluvialis oil · 12,000 mcg12 mgper 1 Softgel(s)DSLD:320059
- ProCaps LaboratoriesAstaxanthin 4000 mcgHaematococcus pluvialis oil4,000 mcgper 1 Softgel(s)DSLD:277590
- ProCaps LaboratoriesMaximum Krill Omega-3150 mcgper 2 Capsule(s)DSLD:57862
- ProCaps LaboratoriesMaximum L+Z with AstaxanthinHaematococcus pluvialis oil · 4,000 mcg4 mgper 1 Capsule(s)DSLD:320152
- ProCaps LaboratoriesMen's Life Rx Complete500 mcgper 5 Capsule(s)DSLD:29714
- ProCaps LaboratoriesMen's Life Rx Complete500 mcgper 1 Packet(s)DSLD:29876
- ProCaps LaboratoriesMen's Life Rx Elite Plus Maximum Essential Omega-3Astaxanthin Note: 1,000 mcg1 mgper 8 Capsule(s)DSLD:29935
- ProCaps LaboratoriesMen's Life Rx UltimateAstaxanthin Note: 1,000 mcg1 mgper 8 Capsule(s)DSLD:4718
- ProCaps LaboratoriesUltimate Krill Omega-3150 mcgper 2 Softgel(s)DSLD:69986
- ProCaps LaboratoriesWomen's Life Rx Complete500 mcgper 5 Capsule(s)DSLD:29715
- ProCaps LaboratoriesWomen's Life Rx Complete500 mcgper 1 Packet(s)DSLD:29878
- ProCaps LaboratoriesWomen's Life Rx EliteAstaxanthin Note: 1,000 mcg1 mgper 6 Capsule(s)DSLD:29931
- ProCaps LaboratoriesWomen's Life Rx EliteAstaxanthin Note: 1,000 mcg1 mgper 6 Capsule(s)DSLD:4728
- ProCaps LaboratoriesWomen's Life Rx Elite Plus Maximum Essential Omega-3Astaxanthin Note: 1,000 mcg1 mgper 8 Capsule(s)DSLD:29945
- ProCaps LaboratoriesWomen's Life Rx UltimateAstaxanthin Note: 1,000 mcg1 mgper 8 Capsule(s)DSLD:4707
- Progressive Professional from Progressive LaboratoriesAstaxantholAstaxanthin, Natural · from stabilized natural astaxanthin beadlets containing other naturally-occurring phytoactive antioxidants4 mgper 1 Vegetable Capsule(s)DSLD:261345
- Progressive Professional from Progressive LaboratoriesBrilliant Vision with Seanol-P500 mgper 3 Vegetable Capsule(s)DSLD:261438
- Progressive Professional from Progressive LaboratoriesKrill Ultra86 mcgper 2 Softgel(s)DSLD:299194
- Protocol For Life BalanceAstaxanthin 10 mgHaematococcus pluvialis Extract · natural Astaxanthin (Form: from Haematococcus pluvialis extract Genus: Haematococcus Species: pluvialis)10 mgper 1 Softgel(s)DSLD:77375
- Protocol For Life BalanceAstaxanthin 12 mgAstaxanthin12 mgper 1 Softgel(s)DSLD:337778
- Protocol For Life BalanceNeptune Krill Oil 1000 mg- Double Strength750 mcgper 1 Softgel(s)DSLD:73063
- Protocol For Life BalanceNeptune Krill Oil 500 mg360 mcgper 2 Softgel(s)DSLD:292274
- Pure EncapsulationsAstaxanthinHaematococcus pluvialis microalgae · Astaxanthin (Form: from Haematococcus pluvialis microalgae Genus: Haematococcus Species: pluvialis)4 mgper 1 Softgel Capsule(s)DSLD:183770
- Pure EncapsulationsAstaxanthinHaematococcus pluvialis microalgae · Astaxanthin (Form: from Haematococcus pluvialis microalgae Genus: Haematococcus Species: pluvialis)4 mgper 1 Softgel Capsule(s)DSLD:183837
- Pure EncapsulationsVitamin A +CarotenoidsAstaxanthin500 mcgper 1 Capsule(s)DSLD:294064
- Pure EncapsulationsVitamin A +CarotenoidsAstaxanthin500 mcgper 1 Capsule(s)DSLD:299741
- Pure EssenceVisionEssence4 mgper 2 Capsule(s)DSLD:327541
- Pure Label NutritionKrill Oil 1000 mg400 mcgper 2 Capsule(s)DSLD:269590
- Pure PrescriptionsPremium Omega-3600 mcgper 2 Softgel(s)DSLD:228209
- Pure SynergySuperPure Astaxanthin6 mgper 1 Capsule(s)DSLD:246681
- Puritan's PrideAll In One Omega with Vitamin D320 mcgper 2 Softgel(s)DSLD:286438
- Puritan's PrideAstaxanthin 10 mgHaematococcus pluvialis10 mgper 1 Softgel(s)DSLD:318303
- Puritan's PrideAstaxanthin 10 mgHaematococcus pluvialis10 mgper 1 Softgel(s)DSLD:318304
- Puritan's PrideAstaxanthin 10 mg10 mgper 1 Softgel(s)DSLD:62082
- Puritan's PrideAstaxanthin 5 mgHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)5 mgper 1 Softgel(s)DSLD:285215
- Puritan's PrideAstaxanthin 5 mgHaematococcus pluvialis5 mgper 1 Softgel(s)DSLD:286423
- Puritan's PrideKrill Oil 500 mg101 mcgper 1 Softgel(s)DSLD:286006
- Puritan's PrideNatural Astaxanthin 10 mgHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)10 mgper 1 Softgel(s)DSLD:285212
- Puritan's PrideNatural Astaxanthin 10 mgHaematococcus pluvialis10 mgper 1 Softgel(s)DSLD:286424
- Puritan's PrideNatural Astaxanthin 10 mgHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)10 mgper 1 Softgel(s)DSLD:76774
- Puritan's PrideNatural Astaxanthin 5 mgHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)5 mgper 1 Softgel(s)DSLD:76683
- Puritan's PrideRed Krill Oil 1000 mg200 mcgper 1 Softgel(s)DSLD:286008
- Purity LabsAntarctic Krill Oil800 mcgper 2 Softgel(s)DSLD:313927
- Purity LabsOrganic AstaxanthinAstaxanthin · organic13 mgper 2 Vegan Tablet(s)DSLD:313930
- Purity ProductsAsta Gummies Mixed Berry Flavor!Phaffia rhodozyma · Astaxanthin (Form: from Phaffia rhodozyma Genus: Phaffia Species: rhodozyma) (Alt. Name: Astaferm)12 mgper 1 Gummy(ies)DSLD:243244
- Purity ProductsAstaFX4 mgper 2 Capsule(s)DSLD:209887
- Purity ProductsAstaFX4 mgper 2 Vegetarian Capsule(s)DSLD:240408
- Purity ProductsAstaOmegaHaematococcus pluvialis Algae extract4 mgper 2 Softgel(s)DSLD:243249
- Purity ProductsOptiKrill 500 Lemon-Lime FlavorHaematococcus pluvialis · natural Astaxanthin (Form: from Krill Oil, and Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)500 mcgper 2 Softgel(s)DSLD:210013
- PuriumBio RegenAstaxanthin94 mgper 2 Capsule(s)DSLD:296258
- PuriumSuper Xanthin8 mgper 2 Capsule(s)DSLD:255910
- PuriumSuper Xanthin8 mgper 2 Capsule(s)DSLD:255911
- Purium Health ProductsSuper XanthinAstaREAL extract · Total Astaxanthin (Form: as AstaREAL extract)8 mgper 2 Capsule(s)DSLD:73900
- QualiaQualia NightHaematococcus pluvialis Microalgae extract33 mgper 4 Vegetarian Capsule(s)DSLD:239672
- Quality of LifeAstaxanthin-SRAstaxanthin3 mgper 1 Vegetarian Softgel(s)DSLD:261646
- Rejuvenation ScienceMaximum Vitality100 mcgper 2 Tablet(s)DSLD:206219
- Renew LifeNorwegian Gold Kids DHA Fruit Punch Flavor250 mcgper 2 Softgel(s)DSLD:250903
- Renew LifeOmega Smart Kids DHA225 mcgper 2 Softgel(s)DSLD:38140
- Renew Life Norwegian GoldKrill Omega Natural Orange Flavor1,240 mcgper 1 Softgel(s)DSLD:179574
- Renew Life Norwegian GoldKrill Omega Natural Orange Flavor620 mcgper 1 Softgel(s)DSLD:48132
- Reserveage BeautyVegan Collagen Builder Gummies Cherry FlavoredAstaxanthin, Natural4 mgper 2 Gummy(ies)DSLD:327287
- ResVitaleAstaxanthin 8 mgH. pluvialis microalgae · AstaPure(TM) Astaxanthin (Form: from H. pluvialis microalgae)8 mgper 1 Vegetarian Capsule(s)DSLD:14095
- Schiff MegaRedHigh Concentration Omega-3 Krill Oil 750 mgKrill Oil · Astaxanthin (Form: from Krill Oil) Note: At time of manufacture.225 mcgper 1 Softgel(s)DSLD:65417
- Schiff MegaRedSuperior Omega-3 Krill Oil 350 mgKrill Oil · Astaxanthin (Form: from Krill Oil) Note: At time of manufacture.17 mcgper 1 Softgel(s)DSLD:213028
- Schiff MegaRedSuperior Omega-3 Krill Oil 350 mgKrill Oil · at time of manufacture17 mcgper 1 Softgel(s)DSLD:264034
- Schiff MegaRedSuperior Omega-3 Krill Oil Ultra Strength 1000 mgKrill Oil · Astaxanthin (Form: from Krill Oil) Note: At time of manufacture.50 mcgper 1 Softgel(s)DSLD:241060
- Schiff MegaRedSuperior Omega-3 Krill Oil Ultra Strength 1000 mgKrill Oil50 mcgper 1 Softgel(s)DSLD:264032
- Seeking HealthOptimal Krill OilHaematococcus pluvialis Algae extract · AstaREAL natural Astaxanthin (Form: from Haematococcus pluvialis Algae extract Genus: Haematococcus Species: pluvialis)12 mgper 2 Softgel(s)DSLD:174640
- ShakleeCarotoMaxHaematococcus pluvialis400 mcgper 1 Softgel(s)DSLD:318621
- ShakleeCarotoMax400 mcgper 1 Softgel(s)DSLD:321909
- Signature SupplementsAstaxanthins 10 mgMarine Algae20 mgper 2 Capsule(s)DSLD:338605
- SmartyPantsBeauty Strawberry CremeAstaZine4 mgper 2 Gummie(s)DSLD:251371
- SmartyPantsBeauty Strawberry CremeAstaZine4 mgper 2 Gummie(s)DSLD:251373
- SolarayAstaxanthin 4 mgHaematococcus pluvialis · from natural source Haematococcus pluvialis4 mgper 1 Softgel(s)DSLD:338213
- SolarayOnce Daily Adult 50+ MultivitaminHaematococcus pluvialis Extract100 mcgper 1 VegCap(s)DSLD:296320
- SolaraySuper Bio Astaxanthin 8 mgHaematococcus pluvialis · Astaxanthin (Form: from natural source Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)8 mgper 1 Vegetarian Capsule(s)DSLD:45170
- SolgarAstaxanthin 10 mgH. pluvialis · Astaxanthin (Form: from H. pluvialis Genus: H. Species: pluvialis)10 mgper 1 Softgel(s)DSLD:73764
- SolgarFull Spectrum Omega20 mcgper 2 Softgel(s)DSLD:304569
- SolgarNatural Astaxanthin 5 mgH. pluvialis · Astaxanthin (Form: from H. pluvialis Genus: H. Species: pluvialis)5 mgper 1 Softgel(s)DSLD:81374
- SolgarNatural Astaxanthin 5 mgH. pluvialis · Astaxanthin (Form: from H. pluvialis Genus: H. Species: pluvialis)5 mgper 1 Softgel(s)DSLD:81021
- Source NaturalsLife Force Green Multiple100 mcgper 3 Tablet(s)DSLD:274838
- Source NaturalsLife Force Multiple100 mcgper 2 Tablet(s)DSLD:272910
- Source NaturalsLife Force Multiple100 mcgper 2 Tablet(s)DSLD:273038
- Source NaturalsLife Force Multiple100 mcgper 2 Tablet(s)DSLD:273040
- Source NaturalsLife Force Multiple100 mcgper 4 Capsule(s)DSLD:273202
- Source NaturalsLife Force Multiple100 mcgper 4 Capsule(s)DSLD:273219
- Source NaturalsLife Force Multiple100 mcgper 4 Capsule(s)DSLD:274820
- Source NaturalsLife Force Multiple100 mcgper 4 Capsule(s)DSLD:274819
- Source NaturalsLife Force Multiple100 mcgper 2 Tablet(s)DSLD:295961
- Source NaturalsLife Force Multiple100 mcgper 2 Tablet(s)DSLD:75453
- Source NaturalsLife Force Multiple No Iron100 mcgper 2 Tablet(s)DSLD:274836
- Source NaturalsMen's Life Force Multiple100 mcgper 3 Tablet(s)DSLD:273495
- Source NaturalsMen's Life Force Multiple100 mcgper 3 Tablet(s)DSLD:296080
- Source NaturalsNKO Neptune Krill Oil 500 mg360 mcgper 2 Softgel(s)DSLD:273337
- Source NaturalsNKO Neptune Krill Oil 500 mg360 mcgper 2 Softgel(s)DSLD:275606
- Source NaturalsWomen's Life Force Multiple100 mcgper 3 Tablet(s)DSLD:273493
- Source NaturalsWomen's Life Force Multiple100 mcgper 3 Tablet(s)DSLD:273494
- Source NaturalsWomen's Life Force Multiple100 mcgper 3 Tablet(s)DSLD:273510
- Source NaturalsWomen's Life Force Multiple100 mcgper 3 Tablet(s)DSLD:296392
- Source NaturalsWomen's Life Force Multiple100 mcgper 3 Tablet(s)DSLD:80839
- Source NaturalsWomen's Life Force Multiple100 mcgper 3 Tablet(s)DSLD:80799
- Source NaturalsWomen's Life Force Multiple100 mcgper 3 Tablet(s)DSLD:80841
- Sports ResearchAstaxanthin 12 mgAstaxanthin12 mgper 1 Softgel(s)DSLD:326237
- Sports ResearchAstaxanthin 6 mgAstaxanthin6 mgper 1 Softgel(s)DSLD:326236
- Spring ValleyAstaxanthin 4 mgHaematococcus pluvialis · Astaxanthin (Form: extract of Haematococcus pluvialis PlantPart: algae Genus: Haematococcus Species: pluvialis)4 mgper 1 Softgel(s)DSLD:211454
- Spring ValleyMen's Multivitamin50 mcgper 2 Tablet(s)DSLD:178316
- Spring ValleyMen's Multivitamin50 mcgper 2 Tablet(s)DSLD:178383
- Spring ValleyWomen's Multivitamin50 mcgper 2 Tablet(s)DSLD:178361
- Spring ValleyWomen's Multivitamin50 mcgper 2 Tablet(s)DSLD:178398
- Spring ValleyWomen's Multivitamin50 mcgper 2 Tablet(s)DSLD:178791
- SR Sports ResearchAstaxanthin 12 mgAstaxanthin12 mgper 1 Liquid Softgel(s)DSLD:268371
- StasisFor NighttimeAlgae Extract · 2% Algae Extract12 mgper 2 Capsule(s)DSLD:325816
- Stonehenge HealthDynamic Krill Oil 1,600 mg2 mgper 2 Softgel(s)DSLD:307928
- Sundown NaturalsAstaxanthin 5 mgHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)10 mgper 2 Softgel(s)DSLD:31507
- SuperSmartAstaxanthin 4 mg4 mgper 1 Softgel(s)DSLD:250141
- SuperSmartDaily 12 mgper 1 Tablet(s)DSLD:339823
- SuperSmartMacula Plus2 mgper 1 Softgel(s)DSLD:332394
- SuperSmartOptiVisionHaematococcus pluvialis Algae Extract · standardized 1% astaxanthin3 mgper 1 Capsule(s)DSLD:332473
- SwansonAstaxanthin & Zeaxanthin4 mgper 1 Softgel(s)DSLD:265003
- SwansonAstaxanthin 12 mg Maximum StrengthHaematococcus pluvialis12 mgper 1 Softgel(s)DSLD:265024
- SwansonAstaxanthin 4 mgnatural Astaxanthin Complex4 mgper 1 Softgel(s)DSLD:265025
- SwansonAstaxanthin 8 mgnatural Astaxanthin Complex · Astaxanthin (Form: from natural Astaxanthin Complex (Form: Supercritical CO2 extract of H. pluvialis PlantPart: algae Genus: H. Species: pluvialis))8 mgper 1 Softgel(s)DSLD:190979
- SwansonEyesAlive Vision Nutritionnatural Astaxanthin Complex · Astaxanthin (Form: from natural Astaxanthin Complex (Form: Supercritical CO2 extract of H. pluvialis PlantPart: algae Genus: H. Species: pluvialis))4 mgper 2 Capsule(s)DSLD:191020
- SwansonOrganic Spirulina & AstaxanthinHaematococcus pluvialis250 mcgper 2 Veggie Tablet(s)DSLD:188787
- SwansonRomega Cognition ComplexHaematococcus pluvialis324 mcgper 1 Softgel(s)DSLD:207750
- SwansonUltimate Ocular AntioxidantHaematococcus pluvialis4 mgper 1 Softgel(s)DSLD:267053
- Swiss BioEnergeticsAstaxanthin 42 mgAstaxanthin Oil42 mgper 1 Softgel(s)DSLD:284221
- Systemic FormulasVista One LQ Membrane Regenerationamount not statedper 0.5 Dropper(s)DSLD:22450
- Terra ELMNTAstaxanthin + Lycopenefrom24 mgper 1 Capsule(s)DSLD:335857
- Terra OriginReds Superfoods Kiwi Strawberry15 mcgper 8.3 Gram(s)DSLD:242093
- TerraVita Premium CollectionAstaxanthin Algae 450 mgAlgae450 mgper 1 Capsule(s)DSLD:287701
- TerraVita Premium CollectionAstaxanthin Algae PowderAlgae1,000 mgper 0.25 Teaspoon(s)DSLD:284313
- TerraVita Premium CollectionAstaxanthin Algae PowderAlgae1,000 mgper 0.25 Teaspoon(s)DSLD:289554
- Terry NaturallyAstaxanthin 6 mgHaematococcus pluvialis microalgae · natural Astaxanthin (Form: extracted from Haematococcus pluvialis microalgae Genus: Haematococcus Species: pluvialis)6 mgper 1 Softgel(s)DSLD:51674
- The Genius BrandGenius BeautyHaematococcus pluvialis Extract · std. to contain 3% astaxanthin150 mgper 3 Capsule(s)DSLD:305638
- The Vitamin ShoppeAstaxanthin 12 mgMicro-Algae · Astaxanthin (Form: from Micro-Algae Genus: Haematococcus Species: pluvialis) (Alt. Name: SolAsta)12 mgper 1 Softgel(s)DSLD:80359
- The Vitamin ShoppeAstaxanthin 12 mgMicro-Algae · Astaxanthin (Form: from Micro-Algae Genus: Haematococcus Species: pluvialis) (Alt. Name: SolAsta)12 mgper 1 Softgel(s)DSLD:80360
- The Vitamin ShoppeAstaxanthin 4 mgMicro-Algae · Astaxanthin (Form: from Micro-Algae Genus: Haematococcus Species: pluvialis) (Alt. Name: SolAsta)4 mgper 1 Softgel(s)DSLD:79807
- The Vitamin ShoppeAstaxanthin 4 mgMicro-Algae · Astaxanthin (Form: from Micro-Algae Genus: Haematococcus Species: pluvialis) (Alt. Name: SolAsta)4 mgper 1 Softgel(s)DSLD:80357
- The Vitamin ShoppeExtra Strength Krill Oil 1000 mg70 mgper 1 Softgel(s)DSLD:208846
- The Vitamin ShoppeOcular SupportAlgae · Astaxanthin (Form: from Algae Genus: Haematococcus Species: pluvialis) (Alt. Name: Zanthin)6 mgper 2 Softgel(s)DSLD:55439
- The Vitamin ShoppeUltimate Man50 mcgper 2 Tablet(s)DSLD:203634
- The Vitamin ShoppeUltimate Man50 mcgper 2 Tablet(s)DSLD:203641
- The Vitamin ShoppeUltimate Man50 mcgper 2 Tablet(s)DSLD:27108
- The Vitamin ShoppeUltimate Man50 mcgper 2 Tablet(s)DSLD:68970
- The Vitamin ShoppeUltimate Woman50 mcgper 2 Tablet(s)DSLD:204867
- The Vitamin ShoppeUltimate Woman50 mcgper 2 Tablet(s)DSLD:204925
- The Vitamin ShoppeUltimate Woman50 mcgper 2 Tablet(s)DSLD:68972
- The Vitamin ShoppeUltimate Woman No Iron50 mcgper 2 Tablet(s)DSLD:204124
- The Vitamin ShoppeUltimate Woman No Iron50 mcgper 2 Tablet(s)DSLD:217717
- Thrive NaturalsAntarctic Krill Oil Complex 1500 mg2,000 mcgper 2 Softgel(s)DSLD:214027
- Tishcon Corp.Freedom ETS Inflammation FightersAstaxanthin (Alt. Name: AstaZine) Note: natural6 mgper 3 Softgel(s)DSLD:243428
- Tishcon Corp.Freedom ETS Inflammation FightersAstaxanthin (Alt. Name: AstaZine) Note: natural6 mgper 3 Softgel(s)DSLD:243478
- Tishcon Corp.Freedom Softgels12 mgper 2 Softgel(s)DSLD:267675
- Tishcon Corp.Freedom Softgels6 mgper 2 Softgel(s)DSLD:272816
- Tishcon Corp.Livogen PlusHaematococcus pluvialis4 mgper 1 Softgel(s)DSLD:243424
- Tishcon Corp.Livogen PlusHaematococcus pluvialis8 mgper 1 Softgel(s)DSLD:243457
- tnvitaminsAstaxanthin 12 mgHaematococcus pluvialis algae · Astaxanthin (Form: from Haematococcus pluvialis algae Genus: Haematococcus Species: pluvialis)12 mgper 1 Softgel(s)DSLD:217695
- tnvitaminsRed Krill Oil 1000 mg300 mcgper 1 Softgel(s)DSLD:217437
- tnvitaminsUltra Potent Omega-3 Antarctic Krill Oil with Astaxanthin 1000 mg200 mcgper 2 Softgel(s)DSLD:336957
- Tropical OasisLiquid 20/20 Vision4 mgper 30 mLDSLD:258884
- True HealthDr. Cutler's Healthy Vision Complete4 mgper 2 Capsule(s)DSLD:206220
- True HealthDr. Cutler's JointFlex CompleteAstaxanthin · AstaReal (Form: contains 1.8% Astaxanthin)10 mgper 3 Capsule(s)DSLD:16684
- up&upAstaxanthin 4 mg4 mgper 1 Softgel(s)DSLD:19950
- Vibrant HealthMaximum Vibrance Vanilla Bean4 mgper 20.615 Gram(s)DSLD:221048
- Vibrant HealthMaximum Vibrance Vanilla Bean4 mgper 20.615 Gram(s)DSLD:221080
- Vibrant HealthSpectrum VibranceHaematococcus pluvialis · Astaxanthin (Form: from 267 mg Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)4 mgper 6.14 Gram(s)DSLD:221195
- Vibrant HealthSpectrum VibranceAstaxanthin Note: from4 mgper 6.14 Gram(s)DSLD:221257
- Village VitalityKrill Oil500 mcgper 1 Softgel(s)DSLD:310246
- VisiViteBlue Light MPOD FormulaHaematococcus pluvialis1 mgper 1 Vegetarian Capsule(s)DSLD:292317
- VisiViteNightSight FormulaHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)1 mgper 1 Vegetarian Capsule(s)DSLD:205780
- Vita LogicSmart SkinHaematococcus pluvialis · Astaxanthin extract (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)2 mgper 2 Capsule(s)DSLD:248328
- VitaCeutical LabsKrill Oil500 mcgper 1 Softgel(s)DSLD:53560
- VitacostMen's Total HealthHaematoccocus pluvialis microalgae · Astaxanthin (Form: extract of Haematoccocus pluvialis microalgae Genus: Haematoccocus Species: pluvialis)50 mcgper 2 Tablet(s)DSLD:207683
- Vitality For LifeCollagen Boost4 mgper 12 Gram(s)DSLD:334742
- Vitamer LaboratoriesKrill Oil500 mcgper 1 Softgel(s)DSLD:23274
- Vitamer LaboratoriesKrill Oil500 mcgper 1 Softgel(s)DSLD:67592
- Vitamin Science Inc.RBI Vision PerformanceAstaxanthin Note: natural extract1 mgper 1 Capsule(s)DSLD:46049
- Vitamin WorldAstaxanthin 10 mgHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)10 mgper 1 Softgel(s)DSLD:1316
- Vitamin WorldAstaxanthin 5 mgHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)5 mgper 1 Softgel(s)DSLD:65905
- ViteyesBlue Light Defender +Haematococcus pluvialis · AstaReal Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)4 mgper 1 Capsule(s)DSLD:239897
- ViteyesBlue Light Defender Kids Natural Chocolate Berry FlavorHaematococcus pluvialis · AstaReal Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)1 mgper 1 Soft Chew(s)DSLD:240471
- Viva LabsKrill Oil1.6 mgper 2 Caplique(R) Capsule(s)DSLD:206709
- Viva NaturalsAstaxanthin 12 mgHaematococcus pluvialis12 mgper 1 Softgel(s)DSLD:248009
- Viva NaturalsAstaxanthin 4 mgHaematococcus pluvialis4 mgper 1 Softgel(s)DSLD:247998
- We Like VitaminsAstaxanthin 10 mgHaematococcus pluvialis Extract · natural Astaxanthin (Form: from Haematococcus pluvialis extract Genus: Haematococcus Species: pluvialis)10 mgper 1 Softgel(s)DSLD:244124
- Weil LifestyleDaily Antioxidant750 mcgper 1 Vegetarian Capsule(s)DSLD:45285
- Whitaker NutritionEyedrateHaematococcus pluvialis Algae Extract2 mgper 2 Softgel(s)DSLD:313217
- WholeHealthHigh Potency Krill Oil1.5 mgper 2 Soft Gel(s)DSLD:248488
- Wholesome WellnessWhole Food Multivitamin for WomenAlgaeamount not statedper 2 Tablet(s)DSLD:278402
- Wiley's FinestBold Vision ProactiveHaematococcus pluvialis2 mgper 2 Softgel(s)DSLD:178215
- Wiley's Finest Wild Alaskan Fish Oil Orange BurstAstaxanthin Note: (5-15 mcg)15 mcgper 1 tspDSLD:55934
- Williams NutritionVision AdvantageAstaxanthin6 mgper 3 Capsule(s)DSLD:323061
- Wonder LaboratoriesAstaxanthin 6 mgHaematococcus pluvialis · Astaxanthin (Form: from Haematococcus pluvialis Genus: Haematococcus Species: pluvialis)6 mgper 1 Softgel(s)DSLD:215142
- Wonder LaboratoriesAstaxanthin 6 mg6 mgper 1 Softgel(s)DSLD:260737
- XtendlifeOmega 3/DHA PlusHaematococcus pluvialis600 mcgper 2 Softgel(s)DSLD:331304
- XtendlifeOmega 3/QH Premium CoQ10Haematococcus pluvialis600 mcgper 2 Softgel(s)DSLD:331305
- XtendlifeTotal Balance Children'sHaematococcus pluvialis352 mcgper 3 Tablet(s)DSLD:318023
- XtendlifeTotal Balance Men's PremiumHaematococcus pluvialis800 mcgper 7 Tablet(s)DSLD:331309
- XtendlifeTotal Balance Unisex PremiumHaematococcus pluvialis800 mcgper 6 Tablet(s)DSLD:283408
- XtendlifeTotal Balance Women's PremiumHaematococcus pluvialis800 mcgper 7 Tablet(s)DSLD:331312
- XYMOGENLipiChol2 mgper 2 Capsule(s)DSLD:49562
- Yuen Diing EnterpriseVision HealthRed Algae extract150 mgper 1 Capsule(s)DSLD:328734
- Zenith LabsVision 20Haematococcus pluvialis, Powder12 mgper 1 Capsule(s)DSLD:326189
- zoltDreamy + Collagen Boost Ginger Honey Tea250 mgper 4.35 Gram(s)DSLD:249546
- zoltEven + Collagen Boost Lime Mint1 mgper 5.18 Gram(s)DSLD:249550
- zolt.Dreamy + Collagen Boost Ginger Honey TeaHaematococcus pluvialis · 2.5%10 mgper 4 Gram(s)DSLD:296880
- zolt.Even + Collagen Boost Lime MintHaematococcus pluvialis · astaxanthin powder (2.5%)40 mgper 5 Gram(s)DSLD:296883
- zolt.Even +Collagen BoostHaematococcus pluvialis · astaxanthin powder (2.5%)40 mgper 5 Gram(s)DSLD:296877
- zolt.Well Dreamy +Collagen BoostHaematococcus pluvialis10 mgper 4 Gram(s)DSLD:296878
Label record: NIH Office of Dietary Supplements · CC0
Registered, and not reported
- Source
- ClinicalTrials.gov
- Intervention
- astaxanthin
- Status
- Completed, terminated or suspended
- Results posted
- No
Trials without posted results
44 trials
44 registered trials without posted results · Overdue (FDAAA 801): 42
42 past the window2 within it, or no actual date
- NCT07509970completed2026-02-05a university or hospital
- NCT07521423completed2026-02-01a university or hospital
- NCT06429059completed2025-05-22a university or hospitalpast the reporting window
- NCT06768970completed2024-11-15industrypast the reporting window
- NCT05015374completed2024-06-01a university or hospitalpast the reporting window
- NCT07604870completed2024-04-30a university or hospitalpast the reporting window
- NCT06511960completed2024-01-01a university or hospitalpast the reporting window
- NCT06247137completed2022-12-30a university or hospitalpast the reporting window
- NCT05437601completed2022-12-19a university or hospitalpast the reporting window
- NCT04784234terminated— company was bought and discontinued producing supplement2022-10-27a university or hospitalpast the reporting window
- NCT05376501completed2022-10-01industrypast the reporting window
- NCT05409092completed2022-07-30a university or hospitalpast the reporting window
Show the remaining 32
- NCT06593535completed2022-07-17a university or hospitalpast the reporting window
- NCT06045377completed2022-06-25a university or hospitalpast the reporting window
- NCT04071977completed2021-10-31a university or hospitalpast the reporting window
- NCT05282355completed2021-07-02a university or hospitalpast the reporting window
- NCT03310359completed2021-03-31a university or hospitalpast the reporting window
- NCT05508529completed2021-03-01industrypast the reporting window
- NCT04249128completed2021-01-28industrypast the reporting window
- NCT03702374completed2020-11-30a university or hospitalpast the reporting window
- NCT03991286completed2020-11-01a university or hospitalpast the reporting window
- NCT04048031completed2020-09-30a university or hospitalpast the reporting window
- NCT02310087completed2019-01a university or hospitalpast the reporting window
- NCT03807050completed2018-12-23industrypast the reporting window
- NCT04583722completed2018-11-30a university or hospitalpast the reporting window
- NCT03460860completed2018-10-10industrypast the reporting window
- NCT03906825completed2018-08-13a university or hospitalpast the reporting window
- NCT03470376completed2017-11-15a university or hospitalpast the reporting window
- NCT03368872completed2016-08industrypast the reporting window
- NCT02397811completed2015-12industrypast the reporting window
- NCT02373111completed2015-11a university or hospitalpast the reporting window
- NCT02343497completed2015-09industrypast the reporting window
- NCT02422927completed2015-01a university or hospitalpast the reporting window
- NCT02087033terminated— The study is halted prematurely by sponsoring organization.2014-12a university or hospitalpast the reporting window
- NCT02264938completed2014-07a university or hospitalpast the reporting window
- NCT01647984completed2014-02a university or hospitalpast the reporting window
- NCT02062034completed2013-11a university or hospitalpast the reporting window
- NCT02582424completed2013-08industrypast the reporting window
- NCT06584669completed2013-04-11industrypast the reporting window
- NCT01562080completed2012-06industrypast the reporting window
- NCT01323036completed2011-12a university or hospitalpast the reporting window
- NCT03209895completed2011-06-13industrypast the reporting window
- NCT01087632completed2010-07industrypast the reporting window
- NCT03945526completed2010-06-09a university or hospitalpast the reporting window
Papers screened
1,099 papers
- Compound
- astaxanthin
- Screened
- 1,099
- Admitted
- 12
- Discarded
- 671
- Not read
- 416
- Showing
- 200 of 1,099
Produced a finding12 papers
- PMID:255145622026-10-11
- PMID:260238422026-10-11
- PMID:281150232026-10-05
and 9 more.
Discarded: the wrong intervention557 papers
- PMID:10232558cited by PMID:26023842; not about the subject it would be filed under2026-10-18
- PMID:1032000cited by PMID:26023842; not about the subject it would be filed under2026-10-18
- PMID:11113183cited by PMID:26023842; not about the subject it would be filed under2026-10-18
- PMID:11172341cited by PMID:26023842; not about the subject it would be filed under2026-10-18
- PMID:11830333cited by PMID:26023842; not about the subject it would be filed under2026-10-18
- PMID:12184814cited by PMID:26023842; not about the subject it would be filed under2026-10-18
- PMID:12391245cited by PMID:26023842; not about the subject it would be filed under2026-10-18
- PMID:15135378cited by PMID:26023842; not about the subject it would be filed under2026-10-18
- PMID:15345651cited by PMID:26023842; not about the subject it would be filed under2026-10-18
- PMID:15686620cited by PMID:26023842; not about the subject it would be filed under2026-10-18
- PMID:16537970cited by PMID:26023842; not about the subject it would be filed under2026-10-18
- PMID:16814559cited by PMID:26023842; not about the subject it would be filed under2026-10-18
and 545 more.
Discarded: no extractable result39 papers
- PMID:25871290no claim extracted — direction_not_in_words2026-10-11
- PMID:26261486claims extracted but the two passes did not agree2026-10-11
- PMID:28170435claims extracted but refused by the deterministic validators2026-10-05
and 36 more.
Discarded: not retrievable34 papers
- PMID:14407094no PMID parsed, abstract under 200 characters, or no record returned by efetch2026-10-18
- PMID:21254351no PMID parsed, abstract under 200 characters, or no record returned by efetch2026-10-18
- PMID:4088069no PMID parsed, abstract under 200 characters, or no record returned by efetch2026-10-17
- PMID:5321443no PMID parsed, abstract under 200 characters, or no record returned by efetch2026-10-17
- PMID:7329314no PMID parsed, abstract under 200 characters, or no record returned by efetch2026-10-17
- PMID:8015469no PMID parsed, abstract under 200 characters, or no record returned by efetch2026-10-17
- PMID:15190135no PMID parsed, abstract under 200 characters, or no record returned by efetch2026-10-16
- PMID:15843671no PMID parsed, abstract under 200 characters, or no record returned by efetch2026-10-16
- PMID:2648148no PMID parsed, abstract under 200 characters, or no record returned by efetch2026-10-16
- PMID:672633no PMID parsed, abstract under 200 characters, or no record returned by efetch2026-10-16
- PMID:7251979no PMID parsed, abstract under 200 characters, or no record returned by efetch2026-10-16
- PMID:1591855no PMID parsed, abstract under 200 characters, or no record returned by efetch2026-10-15
and 22 more.
Discarded: an endpoint this vocabulary does not hold25 papers
- PMID:23519150no claim extracted — no_outcome_node — measured: retinal ganglion cell apoptosis in db/db mouse retina; retinal tissue oxidative stress markers (superoxide anion, MDA, 8-OHdG, MnSOD activity) | retinal tissue malondialdehyde and 8-OHdG as oxidative stress markers2026-10-11
- PMID:23538867no claim extracted — no_outcome_node — measured: cell viability by MTT assay in MPP+-treated differentiated PC12 cells; Sp1 and NR1 expression | cell viability by MTT assay in MPP+-treated PC12 cells2026-10-11
- PMID:23852435no claim extracted — no_outcome_node — measured: hepatic ER stress marker expression and liver ROS production in mouse liver tissue; hepatic lipid accumulation by Oil red O staining | hepatic endoplasmic reticulum stress marker expression, tissue immunoblot2026-10-11
- PMID:25072152claims extracted but the object named resolved to no node — recorded in candidate_nodes (ADR-0070)2026-10-11
- PMID:25528957no claim extracted — no_outcome_node — measured: brain edema, blood-brain barrier permeability and neurological function score in rat subarachnoid hemorrhage | brain edema and neurological function score after experimental subarachnoid hemorrhage in rats2026-10-11
- PMID:26729100no claim extracted — no_outcome_node — measured: IFN-γ and IL-2 secretion by LPS- or Con A-stimulated cultured lymphocytes, ELISA | IFN-γ and IL-2 secretion by cultured splenic lymphocytes, ELISA2026-10-11
- PMID:27034843no claim extracted — no_outcome_node — measured: mitochondrial H2O2 fluorescence (HyperMito sensor) in cultured hippocampal neurons; NFATc4-eGFP nuclear/cytoplasmic ratio; RyR2 mRNA, qPCR | mitochondrial H2O2 production by HyperMito fluorescence in cultured neurons2026-10-11
- PMID:27023003claims extracted but the object named resolved to no node — recorded in candidate_nodes (ADR-0070)2026-10-05
- PMID:28128352claims extracted but the object named resolved to no node — recorded in candidate_nodes (ADR-0070)2026-10-05
and 16 more.
Discarded: another reason, stated per paper15 papers
- PMID:34360729record read only — no claim pass ran (ADR-0092 §2)2026-10-12
- PMID:34919379record read only — no claim pass ran (ADR-0092 §2)2026-10-12
- PMID:35035906record read only — no claim pass ran (ADR-0092 §2)2026-10-12
- PMID:35056816record read only — no claim pass ran (ADR-0092 §2)2026-10-12
- PMID:35261927record read only — no claim pass ran (ADR-0092 §2)2026-10-12
- PMID:35323505record read only — no claim pass ran (ADR-0092 §2)2026-10-12
- PMID:35646393record read only — no claim pass ran (ADR-0092 §2)2026-10-12
- PMID:35794254record read only — no claim pass ran (ADR-0092 §2)2026-10-12
- PMID:35814201record read only — no claim pass ran (ADR-0092 §2)2026-10-12
- PMID:37888449record read only — no claim pass ran (ADR-0092 §2)2026-10-12
- PMID:40563347record read only — no claim pass ran (ADR-0092 §2)2026-10-12
- PMID:41710469record read only — no claim pass ran (ADR-0092 §2)2026-10-12
and 3 more.
Discarded: no comparator1 paper
and 1 more.
Not read yet416 papers
- PMID:199966872026-10-18
- PMID:210555042026-10-18
- PMID:220083072026-10-18
- PMID:248602432026-10-18
- PMID:254501802026-10-18
- PMID:257610532026-10-18
- PMID:115947772026-10-17
- PMID:118764992026-10-17
- PMID:173470062026-10-17
- PMID:246882162026-10-17
- PMID:209628972026-10-16
- PMID:227072632026-10-16
and 404 more.
Measured, not recorded
- Compound
- astaxanthin
- Endpoints measured
- 1,329 endpoints
- Recorded as a finding
- No
Show what was measured
apoptosis of retinal ganglion cells (RGCs)
decreases
astaxanthin was shown to reduce the apoptosis of RGCs and improve the levels of oxidative stress markers
PMID:23519150 · one of two readings recorded this
hydrogen peroxide-induced apoptosis
decreases
astaxanthin attenuated hydrogen peroxide(H2O2)-induced apoptosis in the transformed rat retinal ganglion cell line RGC-5
PMID:23519150 · one of two readings recorded this
oxidative stress markers (superoxide anion, MDA, 8-OHdG, MnSOD activity)
modulates
astaxanthin was shown to reduce the apoptosis of RGCs and improve the levels of oxidative stress markers
PMID:23519150 · one of two readings recorded this
PC12 cell viability and Sp1/NR1 mRNA and protein expression
increases, p = 0.01
Following co-treatment with ATX and MPP+, cell viability was significantly increased, and Sp1 and NR1 mRNA and protein were decreased, compared with the MPP+ groups (p < 0.01)
PMID:23538867 · one of two readings recorded this
PC12 cell viability by MTT after MPP+; Sp1 and NR1 mRNA (real-time PCR) and protein (western blot); Sp1 nuclear translocation by immunofluorescence
increases, p = 0.01
Not recorded as a finding: this platform holds no node for the endpoint
Following co-treatment with ATX and MPP+, cell viability was significantly increased, and Sp1 and NR1 mRNA and protein were decreased, compared with the MPP+ groups (p < 0.01).
PMID:23538867 · one of two readings recorded this
PC12 cell viability by MTT assay, and Sp1 and NR1 mRNA and protein by qPCR and western blot, in MPP+-treated cells
increases, cell viability significantly increased with ATX plus MPP+ compared with MPP+ alone
Not recorded as a finding: this platform holds no node for the endpoint
Following co-treatment with ATX and MPP+, cell viability was significantly increased, and Sp1 and NR1 mRNA and protein were decreased, compared with the MPP+ groups (p < 0.01).
PMID:23538867 · one of two readings recorded this
PC12 cell viability
decreases
PC12 cell viability was significantly reduced by MPP+ treatment
PMID:23538867 · one of two readings recorded this
protection of PC12 cells from MPP+ oxidative stress via Sp1 expression
decreases
mithracycin A protected PC12 cells from oxidative stress caused by MPP+ by specifically inhibiting the expression of Sp1
PMID:23538867 · one of two readings recorded this
Sp1 and NR1 mRNA and protein expression
decreases, p = 0.01
Following co-treatment with ATX and MPP+, cell viability was significantly increased, and Sp1 and NR1 mRNA and protein were decreased, compared with the MPP+ groups (p < 0.01)
PMID:23538867 · one of two readings recorded this
Sp1 and NR1 mRNA and protein expression
increases, p = 0.01
The expression of Sp1 and NR1 mRNA and protein were increased compared with the control (p < 0.01)
PMID:23538867 · one of two readings recorded this
Sp1 nuclear translocation
decreases
cell immunofluorescence revealed that ATX could suppress Sp1 nuclear transfer
PMID:23538867 · one of two readings recorded this
hepatic JNK1 activation, IKKβ phosphorylation and NF-κB p65 nuclear translocation
decreases
This reduction was accompanied by reduced activation of JNK1 and I kappa B kinase β phosphorylation and nuclear factor-kappa B p65 nuclear translocation in ASX-treated HFFD mice
PMID:23852435 · one of two readings recorded this
hepatic ROS production, lipid accumulation and ER stress markers (BiP, PERK, p-eIF2α, XBP1, ATF6, caspase 12)
decreases
ASX significantly reversed these changes.
PMID:23852435 · one of two readings recorded this
hepatic ROS production, lipid accumulation by Oil red O, ER stress markers (BiP, PERK, p-eIF2α, XBP1, ATF6, caspase 12), JNK1 and IKKβ phosphorylation, NF-κB p65 nuclear translocation in liver of high fructose-fat diet mice
decreases
Not recorded as a finding: this platform holds no node for the endpoint
ASX significantly reversed these changes.
PMID:23852435 · one of two readings recorded this
plasma CAT activity
increases
CAT activities in M- and H-FO + ASX groups were remarkably higher than HFD group
PMID:24708887 · one of two readings recorded this
plasma CRP
decreases
all three doses of FO + ASX treatment reduced plasma levels of IL-6 and CRP when compared with HFD diet
PMID:24708887 · one of two readings recorded this
plasma GPx activity
increases
H-FO + ASX-fed rats displayed significant SOD and GPx activities when compared with HFD-fed animals
PMID:24708887 · one of two readings recorded this
plasma GSH level
increases
Treatment with all doses of FO + ASX significantly increased GSH levels and total antioxidant capability
PMID:24708887 · one of two readings recorded this
plasma HDL-C
no effect
Although HDL-C levels in plasma in all groups were comparable
PMID:24708887 · one of two readings recorded this
plasma IL-6 and CRP by rat ELISA kits; plasma TG, TC, LDL-C, HDL-C; plasma antioxidant enzymes, GSH, T-AOC, TBARS
decreases
Not recorded as a finding: the intervention held more than the compound
As seen in Figure 3, all three doses of FO + ASX treatment reduced plasma levels of IL-6 and CRP when compared with HFD diet.
PMID:24708887 · one of two readings recorded this
plasma IL-6 and CRP (ELISA), plasma TG, TC, LDL-C and HDL-C, and plasma antioxidant enzymes and TBARS in rats fed a high-fat diet
decreases, all three doses of FO + ASX reduced plasma IL-6 and CRP versus HFD
Not recorded as a finding: the intervention held more than the compound
As seen in Figure 3, all three doses of FO + ASX treatment reduced plasma levels of IL-6 and CRP when compared with HFD diet.
PMID:24708887 · one of two readings recorded this
plasma IL-6
decreases
all three doses of FO + ASX treatment reduced plasma levels of IL-6 and CRP when compared with HFD diet
PMID:24708887 · one of two readings recorded this
plasma LDL-C
decreases
rats administered with FO + ASX had markedly lower plasma TC and LDL-C levels than the HFD-fed animals
PMID:24708887 · one of two readings recorded this
plasma SOD activity
increases
H-FO + ASX-fed rats displayed significant SOD and GPx activities when compared with HFD-fed animals
PMID:24708887 · one of two readings recorded this
plasma TBARS
decreases
FO + ASX treatment also had substantially reduced content of TBARS relative to HFD diet
PMID:24708887 · one of two readings recorded this
plasma total antioxidant capability (T-AOC)
increases
Treatment with all doses of FO + ASX significantly increased GSH levels and total antioxidant capability
PMID:24708887 · one of two readings recorded this
plasma total cholesterol (TC)
decreases
rats administered with FO + ASX had markedly lower plasma TC and LDL-C levels than the HFD-fed animals
PMID:24708887 · one of two readings recorded this
plasma triglyceride (TG)
decreases
replacement of the HFD with M- and H-FO + ASX significantly decreased plasma TG levels
PMID:24708887 · one of two readings recorded this
ATX neuroprotection and Akt/Bad activation and cleaved caspase-3 levels
decreases
the PI3K/Akt inhibitor, LY294002, could partially reverse the neuroprotection of ATX in the early period after SAH by downregulating ATX-induced activation of Akt/Bad and upregulating cleaved caspase-3 levels
PMID:25072152 · one of two readings recorded this
cleaved caspase-3 levels
decreases
post-SAH treatment with ATX could cause a significant increase of phosphorylated Akt and Bad levels, along with a significant decrease of cleaved caspase-3 levels in the cortex after SAH
PMID:25072152 · one of two readings recorded this
neurological dysfunction, cerebral edema and blood-brain barrier disruption after subarachnoid hemorrhage in rats
decreases
Not recorded as a finding: no matching outcome node; abstract-only paper, no estimates stated
In addition to the reduced neuronal apoptosis, treatment with ATX could also significantly reduce secondary brain injury characterized by neurological dysfunction, cerebral edema and blood-brain barrier disruption.
PMID:25072152 · one of two readings recorded this
neurological dysfunction, cerebral edema, blood-brain barrier disruption, neuronal apoptosis and cortical phosphorylated Akt/Bad and cleaved caspase-3 in rats after subarachnoid hemorrhage
decreases
Not recorded as a finding: this platform holds no node for the endpoint
In addition to the reduced neuronal apoptosis, treatment with ATX could also significantly reduce secondary brain injury characterized by neurological dysfunction, cerebral edema and blood-brain barrier disruption.
PMID:25072152 · one of two readings recorded this
phosphorylated Akt and Bad levels
increases
post-SAH treatment with ATX could cause a significant increase of phosphorylated Akt and Bad levels, along with a significant decrease of cleaved caspase-3 levels in the cortex after SAH
PMID:25072152 · one of two readings recorded this
secondary brain injury (neurological dysfunction, cerebral edema, blood-brain barrier disruption)
decreases
treatment with ATX could also significantly reduce secondary brain injury characterized by neurological dysfunction, cerebral edema and blood-brain barrier disruption
PMID:25072152 · one of two readings recorded this
body weight
no effect
BW/day 0 (g) | 148.4 ± 8.4 | 158.8 ± 5.9
PMID:25514562 · one of two readings recorded this
body weight
no effect
BW/day 30 (g) | 267.5 ± 34.9 | 299.1 ± 8.0
PMID:25514562 · one of two readings recorded this
body weight
no effect
BW/day 45 (g) | 324.2 ± 47.5 | 347.9 ± 11.0
PMID:25514562 · one of two readings recorded this
glutathione peroxidase activity in soleus muscle homogenate
increases, approximately 60% higher basal GPX in ASTA group versus C group
Not recorded as a finding: glutathione-peroxidase-activity node covers erythrocyte, blood, plasma or serum, not skeletal muscle tissue
On the other hand, long-term ASTA supplementation improved basal GPX antioxidant defenses in soleus muscles of ASTA group (versus C group) by approximately 60%, although no difference was observed in GR activity.
PMID:25514562 · one of two readings recorded this
plasma FRAP change with exhaustion, ASTA
increases
FRAP activity) after exercise was only confirmed in control group (45% lower), whereas FRAP capacity in ASTA-fed animals increased 62% instead
PMID:25514562 · one of two readings recorded this
plasma FRAP change with exhaustion, control
decreases
FRAP activity) after exercise was only confirmed in control group (45% lower), whereas FRAP capacity in ASTA-fed animals increased 62% instead
PMID:25514562 · one of two readings recorded this
plasma FRAP
modulates
FRAP (µmol Fe2+/min/mL) | 2.16 ± 0.26 | 1.20 ± 0.23 * (C,AE) | 1.57 ± 0.14 * (C,AE) | 2.55 ± 0.45 * (CE, A)
PMID:25514562 · one of two readings recorded this
plasma glucose and total cholesterol concentration, assay and fasting state not stated
no effect, no significant differences between control and ASTA-fed animals
Not recorded as a finding: fasting-blood-glucose requires an overnight fast and total-cholesterol an enzymatic assay, neither stated in the supplied text
No significant differences in glucose or cholesterol concentrations in plasma were observed between control and 1 mg ASTA/kg BW-fed animals after 45 days of supplementation.
PMID:25514562 · one of two readings recorded this
plasma glucose, method not stated
no effect
Not recorded as a finding: fasting-blood-glucose node requires an overnight fast of stated duration; the paper does not state one.
No significant differences in glucose or cholesterol concentrations in plasma were observed between control and 1 mg ASTA/kg BW-fed animals after 45 days of supplementation.
PMID:25514562 · one of two readings recorded this
plasma glucose
no effect
Glucose (mg/dL) | 170.4 ± 33.6 | 170.6 ± 13.3
PMID:25514562 · one of two readings recorded this
plasma heme-iron
no effect
Heme-iron (µg/mL) | 32.8 ± 7.4 | 30.5 ± 6.0 | 25.4 ± 5.6 | 28.2 ± 6.5
PMID:25514562 · one of two readings recorded this
plasma iron, exhausted versus rested ASTA
increases
we observed a 2.6-fold higher concentration of iron ions in C-EX compared to C group, whereas iron content in plasma of ASTA-EX animals was only 80% higher than in ASTA-fed animals
PMID:25514562 · one of two readings recorded this
plasma iron, exhausted versus rested control
increases
we observed a 2.6-fold higher concentration of iron ions in C-EX compared to C group, whereas iron content in plasma of ASTA-EX animals was only 80% higher than in ASTA-fed animals
PMID:25514562 · one of two readings recorded this
plasma iron
decreases
Iron (µg/dL) | 8.70 ± 0.72 | 21.26 ± 4.28 † (C) * (AE), ‡ (A) | 7.43 ± 0.69 ‡ (CE,AE) | 13.33 ± 1.27 * (C,CE), ‡ (A)
PMID:25514562 · one of two readings recorded this
plasma TEAC, ASTA versus control, exhausted
increases
TEAC levels in ASTA and ASTA-EX animals were 22% and 35% higher than in respective C and C-EX groups
PMID:25514562 · one of two readings recorded this
plasma TEAC, ASTA versus control, rested
increases
TEAC levels in ASTA and ASTA-EX animals were 22% and 35% higher than in respective C and C-EX groups
PMID:25514562 · one of two readings recorded this
plasma TEAC change with exhaustion, control
no effect, p = 0.0825
exhaustion did not significantly decrease TEAC antioxidant activity in plasma of ASTA-fed animals, although a slight tendency to diminish was observed in control group (p = 0.0825)
PMID:25514562 · one of two readings recorded this
plasma TEAC
increases
TEAC (nmolEq.Trolox/mL) | 1.73 ± 0.10 | 1.50 ± 0.20 | 2.11 ± 0.07 * (C,CE) | 2.03 ± 0.13 * (CE)
PMID:25514562 · one of two readings recorded this
plasma total cholesterol
no effect
Total cholesterol (mg/dL) | 79.1 ± 6.7 | 82.3 ± 18.7
PMID:25514562 · one of two readings recorded this
plasma triacylglycerol concentration, assay and fasting state not stated
increases, 40% increase in ASTA-fed animals
Not recorded as a finding: serum-triglycerides node requires an enzymatic assay after a stated fast; neither is stated in the supplied text
Although significant 40% increase in triacylglycerol concentration was measured in plasma of ASTA-fed animals, body weight varied equally in both groups (Table 1).
PMID:25514562 · one of two readings recorded this
plasma triacylglycerol percent increase
increases
Although significant 40% increase in triacylglycerol concentration was measured in plasma of ASTA-fed animals
PMID:25514562 · one of two readings recorded this
plasma triacylglycerol
increases
TAG (mg/dL) | 121.8 ± 17.6 | 171.4 ± 26.8 (*)
PMID:25514562 · one of two readings recorded this
plasma uric acid change with exhaustion
increases
uric acid concentrations in plasma of C-EX and ASTA-EX animals increased by 160% in both groups, independently of supplementation
PMID:25514562 · one of two readings recorded this
plasma uric acid
no effect
Uric acid (mg/mL) | 0.70 ± 0.04 | 1.83 ± 0.26 ‡ (C,A) | 0.66 ± 0.04 ‡ (CE,AE) | 1.74 ± 0.10 ‡ (C,A)
PMID:25514562 · one of two readings recorded this
soleus basal GPX activity
increases, n = 6
long-term ASTA supplementation improved basal GPX antioxidant defenses in soleus muscles of ASTA group (versus C group) by approximately 60%
PMID:25514562 · one of two readings recorded this
soleus catalase and xanthine oxidase activity
no effect, n = 6
Catalase (CAT) and xanthine oxidase (XO) activities were unaltered in soleus muscles of all experimental groups
PMID:25514562 · one of two readings recorded this
soleus GPX activity change with exhaustion, ASTA-fed
decreases, n = 6
GPX activities in soleus muscles decreased after exercise in both groups, although the decrease in ASTA-fed animals was more pronounced (30% drop)
PMID:25514562 · one of two readings recorded this
soleus GR activity change with exhaustion
increases, n = 6
Exhaustion caused a 60% increase of GR activity only in muscles of control animals
PMID:25514562 · one of two readings recorded this
soleus GR activity
no effect, n = 6
although no difference was observed in GR activity
PMID:25514562 · one of two readings recorded this
soleus GSH change with exhaustion, ASTA-fed
increases, n = 6
both GSH and protein thiol contents were increased after exhaustion (88% and 53%, respectively)
PMID:25514562 · one of two readings recorded this
soleus GSH change with exhaustion, control
increases, n = 6
in control, exhaustion caused massive drops in protein thiol and GSSG contents (50% and 55%, respectively), but a 26% increase in GSH content
PMID:25514562 · one of two readings recorded this
soleus GSH/GSSG ratio
modulates, n = 6
Ratio GSH/GSSG (U.A.) | 0.233 ± 0.006 | 0.656 ± 0.229 * (C), ‡ (A) | 0.108 ± 0.026 * (C,AE), ‡ (CE) | 0.395 ± 0.072 * (C,A)
PMID:25514562 · one of two readings recorded this
soleus GSH
modulates, n = 6
GSH (nmol/g tissue) | 51.26 ± 0.91 | 64.54 ± 9.30 *(C), ‡ (A), † (AE) | 19.72 ± 3.18 ‡ (C,CE,AE) | 37.14 ± 3.99 * (C), † (CE), ‡ (A)
PMID:25514562 · one of two readings recorded this
soleus GSSG change with exhaustion, ASTA-fed
decreases, n = 6
in ASTA-fed animals, although similar decrease of GSSG content was observed (50%)
PMID:25514562 · one of two readings recorded this
soleus GSSG change with exhaustion, control
decreases, n = 6
in control, exhaustion caused massive drops in protein thiol and GSSG contents (50% and 55%, respectively), but a 26% increase in GSH content
PMID:25514562 · one of two readings recorded this
soleus GSSG
modulates, n = 6
GSSG (nmol/g tissue) | 220.0 ± 4.0 | 98.3 ± 31.2 † (C) | 183.1 ± 33.5 * (AE) | 94.0 ± 14.0 ‡ (C), * (A)
PMID:25514562 · one of two readings recorded this
soleus lipid oxidation products, ASTA-EX versus ASTA
increases, n = 6
Milder increments of lipid oxidation products were measured in ASTA-EX animals (28% higher than ASTA), but no changes in protein oxidation were evidenced
PMID:25514562 · one of two readings recorded this
soleus MnSOD activity, C versus C-EX
no effect
No changes were observed in MnSOD activity between C and C-EX groups
PMID:25514562 · one of two readings recorded this
soleus protein carbonyls, C-EX versus control
increases, n = 6
levels of oxidized lipids (60% higher TBARS levels) and proteins (33% higher protein carbonyls) were significantly different to control
PMID:25514562 · one of two readings recorded this
soleus protein thiol change with exhaustion, ASTA-fed
increases, n = 6
both GSH and protein thiol contents were increased after exhaustion (88% and 53%, respectively)
PMID:25514562 · one of two readings recorded this
soleus protein thiol change with exhaustion, control
decreases, n = 6
in control, exhaustion caused massive drops in protein thiol and GSSG contents (50% and 55%, respectively), but a 26% increase in GSH content
PMID:25514562 · one of two readings recorded this
soleus protein thiols
modulates, n = 6
Protein thiols (µmol-SH/mg prot) | 4.48 ± 1.62 | 2.31 ± 0.34 * (C) | 3.76 ± 0.17 * (CE) | 5.77 ± 2.88
PMID:25514562 · one of two readings recorded this
soleus TBARS (lipid oxidation), C-EX versus control
increases, n = 6
levels of oxidized lipids (60% higher TBARS levels) and proteins (33% higher protein carbonyls) were significantly different to control
PMID:25514562 · one of two readings recorded this
soleus total SOD activity change with exhaustion
increases, n = 6
a 55% increase of total SOD activity in C-EX muscles, but not in ASTA-EX
PMID:25514562 · one of two readings recorded this
time to exhaustion in forced swimming
increases
The elapsed time until exhaustion of forced-swimming activity was 29% higher in ASTA-fed animals (48.2 ± 14.1 min) than in control (37.4 ± 4.0 min)
PMID:25514562 · one of two readings recorded this
brain edema, BBB disruption, cellular apoptosis and neurological dysfunction
decreases
Furthermore, ATX treatment significantly attenuated brain edema, blood-brain barrier (BBB) disruption, cellular apoptosis, and neurological dysfunction in SAH models
PMID:25528957 · one of two readings recorded this
brain edema, blood-brain barrier disruption, cellular apoptosis, neurological dysfunction, and cortical Nrf2, HO-1, NQO-1 and GST-α1 expression in rats after subarachnoid hemorrhage
decreases
Not recorded as a finding: this platform holds no node for the endpoint
Furthermore, ATX treatment significantly attenuated brain edema, blood-brain barrier (BBB) disruption, cellular apoptosis, and neurological dysfunction in SAH models.
PMID:25528957 · one of two readings recorded this
cortical expression of Nrf2-ARE pathway agents (Nrf2, HO-1, NQO-1, GST-α1)
increases
It was observed that administration of ATX post-SAH could up-regulate the cortical expression of these agents, mediated in the Nrf2-ARE pathway at both pretranscriptional and posttranscriptional levels
PMID:25528957 · one of two readings recorded this
cortical Nrf2 and HO-1 expression by Western blot and immunohistochemistry, HO-1, NQO-1, GST-α1 mRNA by real-time PCR, brain edema, blood-brain barrier disruption, apoptosis, neurological function in rats after subarachnoid hemorrhage
decreases
Not recorded as a finding: this platform holds no node for the endpoint
Furthermore, ATX treatment significantly attenuated brain edema, blood-brain barrier (BBB) disruption, cellular apoptosis, and neurological dysfunction in SAH models.
PMID:25528957 · one of two readings recorded this
oxidative damage
decreases
Meanwhile, oxidative damage was reduced
PMID:25528957 · one of two readings recorded this
Akt and Bad phosphorylation
increases
Additionally, ATX administration increased Akt and Bad phosphorylation and further down-regulated the expression of other downstream pro-apoptotic proteins (cytochrome c and caspase-3/9)
PMID:25871290 · one of two readings recorded this
astaxanthin effects on Akt/Bad/caspases with PI3K inhibitor LY294002
decreases
these effects were reversed by the PI3K inhibitor LY294002
PMID:25871290 · one of two readings recorded this
cytochrome c and caspase-3/9 expression
decreases
Additionally, ATX administration increased Akt and Bad phosphorylation and further down-regulated the expression of other downstream pro-apoptotic proteins (cytochrome c and caspase-3/9)
PMID:25871290 · one of two readings recorded this
neutrophil gelatinase-associated lipocalin
decreases
Upon ATX treatment, renal tubular injury and the levels of serum creatinine and neutrophil gelatinase-associated lipocalin were improved
PMID:25871290 · one of two readings recorded this
oxidative stress and tubular apoptosis in kidney
decreases
Furthermore, relief of oxidative stress and tubular apoptosis in rat kidneys post burn was also observed
PMID:25871290 · one of two readings recorded this
renal protective effect, dose-response
increases
Moreover, the protective effect of ATX presents a dose-dependent enhancement
PMID:25871290 · one of two readings recorded this
renal tubular injury
decreases
Upon ATX treatment, renal tubular injury and the levels of serum creatinine and neutrophil gelatinase-associated lipocalin were improved
PMID:25871290 · one of two readings recorded this
serum creatinine and neutrophil gelatinase-associated lipocalin, renal tubular injury, oxidative stress and tubular apoptosis in severely burned rats
Not recorded as a finding: the direction is carried only as a signed number
Upon ATX treatment, renal tubular injury and the levels of serum creatinine and neutrophil gelatinase-associated lipocalin were improved.
PMID:25871290 · one of two readings recorded this
serum creatinine
decreases
Upon ATX treatment, renal tubular injury and the levels of serum creatinine and neutrophil gelatinase-associated lipocalin were improved
PMID:25871290 · one of two readings recorded this
Bax/Bcl-2 ratio and apoptosis markers
decreases
ASX promoted the level of anti-apoptotic Bcl-2 but inhibited the pro-apoptotic Bax, leading to a decline in the ratio of Bax and Bcl-2 as shown by real-time PCR and western blot
PMID:26023842 · one of two readings recorded this
Beclin-1 and LC3 autophagy markers
decreases
Autophagy-related proteins, such as Beclin-1 and LC3, significantly increased due to disordered energy metabolism after IR and ASX reduced the damage caused by autophagy-induced cell necrosis
PMID:26023842 · one of two readings recorded this
hepatic necrotic area (HE histology)
decreases
The low ASX concentration (30 mg/kg) reduced the necrotic area, while the high ASX concentration (60 mg/kg) showed a greater protective effect
PMID:26023842 · one of two readings recorded this
hepatic ROS (DHE staining) and phosphorylation of P38 MAPK, ERK, JNK
decreases
These results suggested that ASX inhibited ROS generation and the phosphorylation of key proteins related to the MAPK family, which may be an essential pathway in mitigating cell apoptosis and autophagy
PMID:26023842 · one of two readings recorded this
serum ALT and AST in normal (non-IR) mice
no effect, n = 8
Thus, ASX and olive oil had no significant effect on normal liver tissue
PMID:26023842 · one of two readings recorded this
serum ALT and AST, IR versus sham
increases, n = 6
The results showed that the enzymes in the IR group were significantly increased compared with the sham group at each point, and this was particularly evident at 8 h
PMID:26023842 · one of two readings recorded this
serum ALT and AST
decreases, n = 6
Following ASX treatment (30 mg/kg or 60 mg/kg), ALT and AST decreased in a dose-dependent manner
PMID:26023842 · one of two readings recorded this
serum IL-6, ELISA
decreases
Not recorded as a finding: Same sentence as TNF-alpha; matrix not in the quote.
ASX reduced the release of TNF-α and IL-6 at each time point.
PMID:26023842 · one of two readings recorded this
serum TNF-alpha, ELISA
decreases
Not recorded as a finding: The only sentence ('ASX reduced the release of TNF-α and IL-6 at each time point') does not name the matrix; serum is stated in the preceding sentence, so the quote is not self-supporting for the circulating-concentration node.
ASX reduced the release of TNF-α and IL-6 at each time point.
PMID:26023842 · one of two readings recorded this
serum TNF-α and IL-6 (ELISA)
decreases, n = 6
ASX reduced the release of TNF-α and IL-6 at each time point
PMID:26023842 · one of two readings recorded this
blood glucose level in diabetic rats, fasting state not stated
decreases
Not recorded as a finding: fasting-blood-glucose node requires venous plasma or serum glucose after an overnight fast; the abstract states neither
In this experiment, AST could availably enhance the body weight and reduce blood glucose levels of DM rats.
PMID:26261486 · one of two readings recorded this
blood glucose
decreases
In this experiment, AST could availably enhance the body weight and reduce blood glucose levels of DM rats
PMID:26261486 · one of two readings recorded this
body weight
increases
In this experiment, AST could availably enhance the body weight and reduce blood glucose levels of DM rats
PMID:26261486 · one of two readings recorded this
caspase-3/9 expression
decreases
decreased the caspase-3/9 expression and promoted the expression of PI3K/Akt in cerebral cortex and hippocampus
PMID:26261486 · one of two readings recorded this
cognitive function
increases
Moreover, AST could observably perfect cognitive function of DM rat
PMID:26261486 · one of two readings recorded this
oxidative stress, nitric oxide synthase activity and inflammatory factors
decreases
Next, the activities of oxidative stress, nitric oxide synthase and inflammation were distinctly diminution in DM rat, after the treatment of AST
PMID:26261486 · one of two readings recorded this
PI3K/Akt expression
increases
decreased the caspase-3/9 expression and promoted the expression of PI3K/Akt in cerebral cortex and hippocampus
PMID:26261486 · one of two readings recorded this
body weight of mice
no effect
The body weight of the animals did not change
PMID:26729100 · one of two readings recorded this
Con A-induced lymphocyte proliferation
no effect
astaxanthin potentiated LPS-induced cell proliferation ex vivo, but was not effective in Con A-stimulated proliferation
PMID:26729100 · one of two readings recorded this
IFN-γ and IL-2 in culture supernatant of LPS- or Con A-stimulated primary splenic lymphocytes, ELISA, in vitro and ex vivo after oral astaxanthin in mice; lymphocyte proliferation by MTT
increases
Not recorded as a finding: this platform holds no node for the endpoint
In addition, a significant, concentration-dependent increase of LPS- induced IFN-γ and Con A- induced IFN-γ and IL-2 production was observed in cells from astaxanthin-administered mice (Table 2).
PMID:26729100 · one of two readings recorded this
IFN-γ and IL-2 production by primary cultured splenic lymphocytes, ELISA, in vitro and ex vivo after oral astaxanthin in mice
increases, concentration-dependent increase of LPS-induced IFN-γ and Con A-induced IFN-γ and IL-2 production in cells from astaxanthin-administered mice
Not recorded as a finding: this platform holds no node for the endpoint
In addition, a significant, concentration-dependent increase of LPS- induced IFN-γ and Con A- induced IFN-γ and IL-2 production was observed in cells from astaxanthin-administered mice (Table 2).
PMID:26729100 · one of two readings recorded this
IFN-γ production, astaxanthin alone
no effect
INF-γ (pg/mL) | 153.5 ± 2.6 | 153.9 ± 1.6 | 156.8 ± 6.4 | 152.5 ± 1.6 | 168.3 ± 29.2 | 840.1 ± 174.5 * | 1099.9 ± 70.7 # | 1037.3 ± 97.3 # | 1074.8 ± 111.7 # | 204.5 ± 54.0 | 1089.9 ± 22.9 * | 1074.5 ± 12.3 | 1119.0 ± 9.2 | 1113.0 ± 7.2
PMID:26729100 · one of two readings recorded this
IFN-γ production, astaxanthin alone
no effect
INF-γ (pg/mL) | 281.2 ± 53.8 | 358.4 ± 70.3 | 455.5 ± 149.0 | 351.8 ± 93.4 | 281.2 ± 53.8 | 632.3 ± 172.1 * | 1027.7 ± 25.2 # | 865.7 ± 152.5 # | 900.6 ± 195.6 # | 281.2 ± 53.8 | 934.1 ± 181.8 * | 1107.9 ± 20.2 # | 1054.2 ± 20.4 # | 1084.2 ± 44.5 #
PMID:26729100 · one of two readings recorded this
IFN-γ production, Con A-stimulated
no effect
INF-γ (pg/mL) | 153.5 ± 2.6 | 153.9 ± 1.6 | 156.8 ± 6.4 | 152.5 ± 1.6 | 168.3 ± 29.2 | 840.1 ± 174.5 * | 1099.9 ± 70.7 # | 1037.3 ± 97.3 # | 1074.8 ± 111.7 # | 204.5 ± 54.0 | 1089.9 ± 22.9 * | 1074.5 ± 12.3 | 1119.0 ± 9.2 | 1113.0 ± 7.2
PMID:26729100 · one of two readings recorded this
IFN-γ production, Con A-stimulated
increases
INF-γ (pg/mL) | 281.2 ± 53.8 | 358.4 ± 70.3 | 455.5 ± 149.0 | 351.8 ± 93.4 | 281.2 ± 53.8 | 632.3 ± 172.1 * | 1027.7 ± 25.2 # | 865.7 ± 152.5 # | 900.6 ± 195.6 # | 281.2 ± 53.8 | 934.1 ± 181.8 * | 1107.9 ± 20.2 # | 1054.2 ± 20.4 # | 1084.2 ± 44.5 #
PMID:26729100 · one of two readings recorded this
IFN-γ production, LPS-stimulated
increases
INF-γ (pg/mL) | 153.5 ± 2.6 | 153.9 ± 1.6 | 156.8 ± 6.4 | 152.5 ± 1.6 | 168.3 ± 29.2 | 840.1 ± 174.5 * | 1099.9 ± 70.7 # | 1037.3 ± 97.3 # | 1074.8 ± 111.7 # | 204.5 ± 54.0 | 1089.9 ± 22.9 * | 1074.5 ± 12.3 | 1119.0 ± 9.2 | 1113.0 ± 7.2
PMID:26729100 · one of two readings recorded this
IFN-γ production, LPS-stimulated
increases
INF-γ (pg/mL) | 281.2 ± 53.8 | 358.4 ± 70.3 | 455.5 ± 149.0 | 351.8 ± 93.4 | 281.2 ± 53.8 | 632.3 ± 172.1 * | 1027.7 ± 25.2 # | 865.7 ± 152.5 # | 900.6 ± 195.6 # | 281.2 ± 53.8 | 934.1 ± 181.8 * | 1107.9 ± 20.2 # | 1054.2 ± 20.4 # | 1084.2 ± 44.5 #
PMID:26729100 · one of two readings recorded this
IL-2 production, astaxanthin alone
no effect
IL-2 (pg/mL) | 18.9 ± 6.3 | 17.4 ± 5.1 | 18.5 ± 6.7 | 19.6 ± 7.4 | – | – | – | – | – | 21.1 ± 5.8 | 242.0 ± 42.1 * | 245.2 ± 39.9 | 242.2 ± 48.3 | 287.6 ± 32.3
PMID:26729100 · one of two readings recorded this
IL-2 production, astaxanthin alone
increases
IL-2 (pg/mL) | 8.6 ± 6.0 | 37.3 ± 23.6 * | 47.9 ± 11.3 * | 56.9 ± 18.0 * | – | – | – | – | – | 21.7 ± 6.1 | 187.5 ± 19.2 * | 231.3 ± 34.9 # | 252.0 ± 7.9 # | 269.9 ± 45.6 #
PMID:26729100 · one of two readings recorded this
IL-2 production, Con A-stimulated
no effect
IL-2 (pg/mL) | 18.9 ± 6.3 | 17.4 ± 5.1 | 18.5 ± 6.7 | 19.6 ± 7.4 | – | – | – | – | – | 21.1 ± 5.8 | 242.0 ± 42.1 * | 245.2 ± 39.9 | 242.2 ± 48.3 | 287.6 ± 32.3
PMID:26729100 · one of two readings recorded this
IL-2 production, Con A-stimulated
increases
IL-2 (pg/mL) | 8.6 ± 6.0 | 37.3 ± 23.6 * | 47.9 ± 11.3 * | 56.9 ± 18.0 * | – | – | – | – | – | 21.7 ± 6.1 | 187.5 ± 19.2 * | 231.3 ± 34.9 # | 252.0 ± 7.9 # | 269.9 ± 45.6 #
PMID:26729100 · one of two readings recorded this
LPS-induced lymphocyte proliferation
increases
astaxanthin potentiated LPS-induced cell proliferation ex vivo, but was not effective in Con A-stimulated proliferation
PMID:26729100 · one of two readings recorded this
LPS- or Con A-induced lymphocyte proliferation
no effect
astaxanthin, even at a high concentration of 300 nM, did not enhance this stimulation
PMID:26729100 · one of two readings recorded this
lymphocyte viability (MTT)
no effect
astaxanthin, in concentrations of 70 and 150 nM, did not affect the viability of lymphocytes after treatment for 48 h
PMID:26729100 · one of two readings recorded this
spleen weight
increases, p = 0.05
a high dose of astaxanthin (7 mg/kg) significantly (p < 0.05) increased the spleen weight
PMID:26729100 · one of two readings recorded this
clinical skin severity score of atopic-dermatitis-like lesions, 0-3 grading of five signs summed
decreases, Vehicle 9.0 ± 0.6 vs AST 3.8 ± 0.7 at day 26
Not recorded as a finding: no outcome node for a murine dermatitis clinical severity score
The skin severity scores of the AST-treated mice were significantly decreased at 26 days compared to the vehicle-treated mice (Vehicle: 9.0 ± 0.6, AST: 3.8 ± 0.7, *p<0.01).
PMID:27023003 · one of two readings recorded this
clinical skin severity score (sum of five signs, 0-3 each), serum total IgE by ELISA, spontaneous scratching bouts, dermal eosinophil and mast cell counts, skin cytokine mRNA and protein in NC/Nga mice
decreases, skin severity score Vehicle 9.0 +/- 0.6 versus AST 3.8 +/- 0.7 at 26 days
Not recorded as a finding: No outcome node for atopic dermatitis severity score, serum IgE or scratching behaviour
The skin severity scores of the AST-treated mice were significantly decreased at 26 days compared to the vehicle-treated mice (Vehicle: 9.0 ± 0.6, AST: 3.8 ± 0.7, *p<0.01).
PMID:27023003 · one of two readings recorded this
clinical skin severity score
decreases, p = 0.01
The skin severity scores of the AST-treated mice were significantly decreased at 26 days compared to the vehicle-treated mice (Vehicle: 9.0 ± 0.6, AST: 3.8 ± 0.7, *p<0.01)
PMID:27023003 · one of two readings recorded this
degranulated mast cell number in dermis
decreases, p = 0.001
(total, Vehicle: 21.2 ± 3.1, AST: 7.9 ± 2.7, de-granulated, Vehicle: 11.3 ± 1.6, AST: 4.1 ± 1.7, *p<0.001)
PMID:27023003 · one of two readings recorded this
eosinophil number in dermis
decreases, p = 0.05
The number of eosinophils was significantly decreased in the dermis of the AST-treated mice compared to the vehicle-treated mice (Vehicle: 3.1 ± 0.6, AST: 0.6 ± 0.5, *p<0.05)
PMID:27023003 · one of two readings recorded this
serum total IgE, ELISA
decreases, significantly decreased versus vehicle, p<0.05
Not recorded as a finding: no outcome node for serum IgE
The serum IgE levels were also significantly decreased in the mice treated with AST for 26 days compared to the vehicle-treated mice (*p<0.05).
PMID:27023003 · one of two readings recorded this
serum total IgE
decreases, p = 0.05
The serum IgE levels were also significantly decreased in the mice treated with AST for 26 days compared to the vehicle-treated mice (*p<0.05)
PMID:27023003 · one of two readings recorded this
skin mRNA and protein of eotaxin, MIF, IL-4, IL-5 and HDC
decreases
AST treatment decreased the mRNA expression levels of eotaxin, MIF, IL-4, IL-5 and HDC
PMID:27023003 · one of two readings recorded this
skin TNF-α and IL-1β expression
no effect
the expression of TNF-α and IL-1β remain unchanged following AST treatment
PMID:27023003 · one of two readings recorded this
spontaneous scratching bouts
decreases
A decrease in scratching behavior was observed after AST treatment, starting on day five and lasting until day 26, compared to that noted for vehicle treatment
PMID:27023003 · one of two readings recorded this
total mast cell number in dermis
decreases, p = 0.001
(total, Vehicle: 21.2 ± 3.1, AST: 7.9 ± 2.7, de-granulated, Vehicle: 11.3 ± 1.6, AST: 4.1 ± 1.7, *p<0.001)
PMID:27023003 · one of two readings recorded this
control neuronal survival
Control neurons presented at least 85% cell survival
PMID:27034843 · one of two readings recorded this
mitochondrial H2O2 content (HyperMito relative fluorescence Ffinal/F0)
decreases
500 nM A βOs induced a significant increase in mitochondrial H2O2 content, which was prevented by preincubation with 0.1 μM ATX
PMID:27034843 · one of two readings recorded this
neuronal cell death
increases
treatment with 100 μM ATX induced 20% cell death
PMID:27034843 · one of two readings recorded this
neuronal cell death
increases
treatment with 250 μM H2O2 elicited 40% neuronal death
PMID:27034843 · one of two readings recorded this
neuronal cell viability (live/dead assay)
no effect
Treatment with ATX concentrations ≤10 μM did not decrease cell viability when compared to control cultures
PMID:27034843 · one of two readings recorded this
NFATc4-GFP nuclear/cytoplasmic ratio
increases, n = 4
incubation of neurons with A βOs for 6 h increased 3-fold the nuclear/cytoplasmic ratio
PMID:27034843 · one of two readings recorded this
NFATc4-GFP nuclear/cytoplasmic ratio
decreases, n = 4
this increase did not occur in neurons pretreated with ATX
PMID:27034843 · one of two readings recorded this
RyR2 mRNA level
decreases
incubation for 6 h with A βOs (500 nM) significantly decreased RyR2 mRNA levels to approximately 54%
PMID:27034843 · one of two readings recorded this
RyR2 mRNA level
increases
Preincubation with ATX (0.10 μM) did not modify RyR2 mRNA levels but resulted in complete prevention of the reduction of RyR2 mRNA levels promoted by A βOs
PMID:27034843 · one of two readings recorded this
RyR2 mRNA level
increases
the general antioxidant agent N-acetyl-L-cysteine (NAC), which is a cellular precursor of glutathione, also protects primary hippocampal neurons from the RyR2 mRNA decrease induced by A βOs
PMID:27034843 · one of two readings recorded this
BAK and BAX protein, ATX vs TBI
decreases, n = 3
ATX application significantly ameliorated the increased expression of BAK and BAX and upregulated the protein expression of BCL-XL compared with the TBI groups
PMID:28115023 · one of two readings recorded this
BCL-XL protein, ATX vs TBI
increases, n = 3
ATX application significantly ameliorated the increased expression of BAK and BAX and upregulated the protein expression of BCL-XL compared with the TBI groups
PMID:28115023 · one of two readings recorded this
body weight, TBI + ATX vs TBI
increases, n = 5
the body weight of mice that received 25-100 mg/kg ATX was significantly increased compared to that of the TBI groups
PMID:28115023 · one of two readings recorded this
body weight, TBI vs control
decreases, n = 5
Compared to the control group, the body weight of the TBI group had decreased significantly when mice were sacrificed 12 days after 4 Gy irradiation
PMID:28115023 · one of two readings recorded this
bone marrow cells, LSK cells and HPCs numbers
increases, n = 5
At day +12 following TBI, ATX-treated mice had increased numbers of BM cells, LSK cells (Lin−Sca-l+c-kit+), and HPCs (Lin−Sca-l−c-kit+), as well as increased percentages of LSK cells and HPCs compared to vehicle-treated mice
PMID:28115023 · one of two readings recorded this
CFU-GM number, ATX vs TBI
increases, n = 6
ATX treatment increased the CFU-GM number in 4 Gy irradiated mice
PMID:28115023 · one of two readings recorded this
CFU-GM number, TBI vs control
decreases, n = 6
compared to the control group, the number of CFU-GM in the TBI group decreased significantly, and ATX treatment increased the CFU-GM number in 4 Gy irradiated mice
PMID:28115023 · one of two readings recorded this
cleaved CASPASE 3 expression, ATX vs TBI
decreases, n = 3
ATX downregulated the expression of cleaved CASPASE 3 in irradiated c-kit-positive cells
PMID:28115023 · one of two readings recorded this
cytochrome C release from mitochondria to cytosol, ATX vs TBI
decreases, n = 5
TBI induced cytochrome C release from the mitochondria to cytosol, while ATX significantly blocked the efflux of cytochrome C from the mitochondria
PMID:28115023 · one of two readings recorded this
donor cell chimerism in competitive BM transplant, 4 Gy + ATX vs 4 Gy
increases, n = 10
At 2 month post-transplantation, we measured donor-derived cells (CD45.2+) in the peripheral blood of recipient mice by FACS
PMID:28115023 · one of two readings recorded this
gamma-H2AX (DNA DSBs) in c-kit-positive cells, ATX vs TBI
decreases, n = 5
treatment with ATX substantially reduced TBI-induced DNA damage in c-kit-positive cells, as shown by the reduced γH2AX level
PMID:28115023 · one of two readings recorded this
gamma-H2AX (DNA DSBs) in c-kit-positive cells, TBI vs control
increases, n = 5
γH2AX staining in irradiated c-kit-positive cells was significantly increased after TBI
PMID:28115023 · one of two readings recorded this
HO-1 and NQO1 expression, ATX
increases, n = 5
ATX also increased the expression of NRF2-targeted proteins HO-1 and NQO1
PMID:28115023 · one of two readings recorded this
lung index
unclear, n = 5
the indices of lung in TBI + ATX groups showed a significant improvement
PMID:28115023 · one of two readings recorded this
NRF2 protein expression and nuclear translocation, TBI vs control
increases, n = 3
TBI significantly upregulated NRF2 protein expression and promoted nuclear translocation; these alterations were enhanced by ATX
PMID:28115023 · one of two readings recorded this
percentage of apoptotic c-kit-positive cells, ATX vs TBI
decreases, n = 5
The percentage of apoptotic cells increased significantly after irradiation compared with non-irradiated cells, but ATX administration markedly reduced this trend
PMID:28115023 · one of two readings recorded this
percentage of apoptotic c-kit-positive cells, TBI vs non-irradiated
increases, n = 5
The percentage of apoptotic cells increased significantly after irradiation compared with non-irradiated cells, but ATX administration markedly reduced this trend
PMID:28115023 · one of two readings recorded this
peripheral blood differentiation (WBC, LY%, NE%, T, B, myeloid), ATX vs TBI
increases, n = 5
Treatment with 50 mg/kg ATX notably rescued impaired differentiation of peripheral blood cells in the mice exposed to 4 Gy radiation
PMID:28115023 · one of two readings recorded this
ROS (DCFDA and MitoSOX, not DHE) in Nrf2-/- c-kit-positive cells, ATX vs TBI
decreases, n = 5
ATX indeed decreased the ROS levels in c-kit-positive cells of irradiated Nrf2
PMID:28115023 · one of two readings recorded this
ROS (DCFDA, DHE, MitoSOX) in c-kit-positive cells, TBI vs non-irradiated
increases, n = 5
the generation of ROS in c-kit-positive cells, which was analyzed by DCFDA, DHE, and MitoSOX staining, was significantly elevated after TBI compared to non-irradiated mice
PMID:28115023 · one of two readings recorded this
ROS detected by DCFDA and MitoSOX in c-kit-positive cells, ATX vs TBI
decreases, n = 5
ATX treatment markedly attenuated the elevation of ROS production detected by DCFDA and MitoSOX, but not DHE
PMID:28115023 · one of two readings recorded this
ROS detected by DHE in c-kit-positive cells, ATX vs TBI
no effect, n = 5
ATX treatment markedly attenuated the elevation of ROS production detected by DCFDA and MitoSOX, but not DHE
PMID:28115023 · one of two readings recorded this
SOD2, CAT and GPX1 enzyme activity, ATX
increases, n = 3
We found that a decreased enzyme activity for SOD2, CAT, and GPX1 was observed in irradiated c-kit-positive cells, which were also enhanced by ATX
PMID:28115023 · one of two readings recorded this
survival after lethal 7.2 Gy irradiation, 30-day Kaplan-Meier, N = 19 per group
increases, n = 19
Not recorded as a finding: Survival after a lethal radiation challenge is not the organism-lifespan node (lifespan from start of observation in a model organism, median or maximum) and no all-cause mortality horizon node fits an irradiation model
In contrast, forty-four percent of the ATX-treated mice remained alive through day +30.
PMID:28115023 · one of two readings recorded this
survival after lethal 7.2 Gy irradiation, Kaplan-Meier over 30 days
increases
Not recorded as a finding: organism-lifespan node is elapsed time to death in a model organism read from a survival curve; paper reports proportion alive at day 30 after a lethal radiation challenge, and the sentence is two-part
In contrast, forty-four percent of the ATX-treated mice remained alive through day +30.
PMID:28115023 · one of two readings recorded this
survival after lethal TBI, control (DMSO) mice
n = 19
None of the control mice survived beyond 15 days after the lethal irradiation
PMID:28115023 · one of two readings recorded this
survival at day +30 after lethal TBI, ATX-treated mice
increases, n = 19
forty-four percent of the ATX-treated mice remained alive through day +30
PMID:28115023 · one of two readings recorded this
thymus index
increases, n = 5
compared with TBI group, the index of thymus of the 50 mg/kg group was significantly rescued
PMID:28115023 · one of two readings recorded this
white blood cells and lymphocyte percentage, TBI vs control
decreases, n = 5
TBI-treated mice exhibited a substantial reduction in WBCs and percentage of lymphocyte cells (including T cells and B cells), while the percentage of neutrophils (NE%) and myeloid cells increased
PMID:28115023 · one of two readings recorded this
Akt and Bad phosphorylation, Ly 294002 + ATX 20 mg/kg vs ATX 20 mg/kg
decreases, n = 8
Ly 294002 significantly reversed the ATX-induced (20 mg/kg) elevation of Akt and Bad phosphorylation in the zone of stasis
PMID:28128352 · one of two readings recorded this
apoptotic cells, Ly 294002 + ATX 20 mg/kg vs ATX 20 mg/kg
increases, n = 8
TUNEL staining indicated that Ly 294002 pretreatment clearly increased the number of positively labeled (brown nuclei) apoptotic cells in the tested zone after treatment with 20 mg/kg ATX
PMID:28128352 · one of two readings recorded this
apoptotic (TUNEL-positive) cells, ATX dose-response
decreases, n = 8
The administration of ATX resulted in a dose-dependent reduction in the number of apoptotic cells compared with the number observed in the vehicle group
PMID:28128352 · one of two readings recorded this
Bcl-xL expression, ATX
no effect, n = 8
Even higher doses of ATX did not effect Bcl-xL expression
PMID:28128352 · one of two readings recorded this
Bcl-xL expression, Ly 294002 + ATX 20 mg/kg
no effect, n = 8
However, Ly 294002 did not influence Bcl-xL expression levels
PMID:28128352 · one of two readings recorded this
burn-wound zone-of-stasis skin tissue homogenate MDA (TBARS kit), SOD and GPx activity, MPO, TNF-alpha, IL-1beta, IL-6 (ELISA), TUNEL apoptosis index, cleaved caspase 3/9, p-Akt, p-Bad in rats given intravenous astaxanthin 30 min after burn
decreases, both medium and high doses markedly decreased MDA levels versus vehicle group
Not recorded as a finding: this platform holds no node for the endpoint
ATX treatment at a low dose (5 mg/kg) resulted in an insignificant decrease in MDA levels compared with those of the vehicle group; however, both the medium and high doses markedly decreased MDA levels.
PMID:28128352 · one of two readings recorded this
cleaved caspase 3 and 9 expression, ATX
decreases, n = 8
all three ATX doses significantly decreased CC3 and CC9 expression levels, and the highest dose (20 mg/kg) exerted the strongest effect
PMID:28128352 · one of two readings recorded this
cytochrome C expression, ATX dose-response
decreases, n = 8
the increased expression of Cyto C post burn was dose-dependently reduced by ATX administration
PMID:28128352 · one of two readings recorded this
IL-1β level, ATX high dose
decreases, n = 8
whereas only high doses of ATX markedly decreased elevated IL-1β levels in the zone of stasis
PMID:28128352 · one of two readings recorded this
MDA level, ATX 5 mg/kg vs vehicle
no effect, n = 8
ATX treatment at a low dose (5 mg/kg) resulted in an insignificant decrease in MDA levels compared with those of the vehicle group
PMID:28128352 · one of two readings recorded this
MDA level, ATX medium and high dose vs vehicle
decreases, n = 8
however, both the medium and high doses markedly decreased MDA levels
PMID:28128352 · one of two readings recorded this
MDA level (lipid peroxidation), burn vs sham
increases, n = 8
Within 6 h after burn injuries, MDA levels were significantly increased in the burn interspaces
PMID:28128352 · one of two readings recorded this
MPO level, ATX
decreases, n = 8
All three ATX doses reduced the elevated MPO levels observed after burn injury, and the 20 mg/kg dose exerted the most significant effect
PMID:28128352 · one of two readings recorded this
Nox4 expression, burn
increases, n = 8
Nox4 expression in the zone of stasis was significantly increased at all four selected time windows following burn injury and peaked at 12 h post burn
PMID:28128352 · one of two readings recorded this
p-Akt and p-Bad expression, ATX dose-response
increases, n = 8
increasing doses of ATX resulted in the further upregulation of p-Akt and p-Bad expression, with a peak observed in the group treated with a dose of 20 mg/kg
PMID:28128352 · one of two readings recorded this
SOD activity, burn
decreases, n = 8
the activity of superoxide dismutase (SOD) in wounds was markedly decreased 12, 24 and 48 h after the burn insults
PMID:28128352 · one of two readings recorded this
SOD and GPx activities, ATX dose-response
increases, n = 8
ATX exerted a dose-dependent effect, increasing SOD and GPx activities after burn injury, and peak activities were detected in the group treated with 20 mg/kg ATX
PMID:28128352 · one of two readings recorded this
TNF-alpha, IL-6, IL-1beta in burn-wound skin homogenate, ELISA
decreases, attenuated burn-induced increases in a dose-dependent manner
Not recorded as a finding: TNF-alpha node is circulating serum or plasma protein; paper measured tissue homogenate
In contrast, we observed that ATX treatment attenuated the burn-induced increases in TNF-α or IL-6 levels in a dose-dependent manner, whereas only high doses of ATX markedly decreased elevated IL-1β levels in the zone of stasis.
PMID:28128352 · one of two readings recorded this
TNF-α and IL-6 levels, ATX dose-response
decreases, n = 8
we observed that ATX treatment attenuated the burn-induced increases in TNF-α or IL-6 levels in a dose-dependent manner
PMID:28128352 · one of two readings recorded this
XO and Nox4 expression, ATX dose-response
decreases, n = 8
The increases in the expression of XO and Nox4 after a burn were markedly downregulated in correlation with increasing ATX doses
PMID:28128352 · one of two readings recorded this
transepidermal water loss (TEWL)
decreases
At 70 days, TEWL in both the 0.01% and 0.1% astaxanthin-supplemented groups was significantly lower than that in the control UVA-irradiated group
PMID:28170435 · one of two readings recorded this
transepidermal water loss (TEWL)
unclear
which demonstrated a trend toward suppression by dietary astaxanthin at 56 days
PMID:28170435 · one of two readings recorded this
Sources cited
16 papers
- Subject
- astaxanthin
- Findings
- 35
- Papers
- 16
A systematic review and meta-analysis of astaxanthin efficacy in male infertility: evidence from clinical and preclinical studies.record2026PMID:417147441 finding
The Effects of Astaxanthin Supplementation on Exercise Recovery Biomarkers and Exercise Performance: A Systematic Review and Meta-Analysis.record2026PMID:421970303 findings
Astaxanthin prevents postovulatory oocyte aging by targeting TNFR2 and inhibiting the TNF signaling pathway.record2025PMID:405983791 finding
Astaxanthin Inhibits STING Carbonylation and Enhances Antiviral Responses.record2024PMID:383912981 finding
Astaxanthin prevents nephrotoxicity through Nrf2/HO-1 pathway.record2024PMID:376832912 findings
Astaxanthin inhibits oxidative stress and apoptosis in diabetic retinopathy.record2023PMID:373434961 finding
Astaxanthin Influence on Health Outcomes of Adults at Risk of Metabolic Syndrome: A Systematic Review and Meta-Analysis.record2022PMID:356311932 findings
Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers: a systematic review and meta-analysis of randomized controlled trials.record2022PMID:350912763 findings
Astaxanthin Protects Dendritic Cells from Lipopolysaccharide-Induced Immune Dysfunction.record2021PMID:342042204 findings
The effects of astaxanthin supplementation on obesity, blood pressure, CRP, glycemic biomarkers, and lipid profile: A meta-analysis of randomized controlled trials.record2020PMID:327556137 findings
High-Dose Astaxanthin Supplementation Suppresses Antioxidant Enzyme Activity during Moderate-Intensity Swimming Training in Mice.record2019PMID:311592111 finding
Astaxanthin alleviated ethanol-induced liver injury by inhibition of oxidative stress and inflammatory responses via blocking of STAT3 activity.record2018PMID:302375783 findings
Astaxanthin attenuates total body irradiation-induced hematopoietic system injury in mice via inhibition of oxidative stress and apoptosis.record2017PMID:281150231 finding
Astaxanthin prevents ischemia-reperfusion injury of the steatotic liver in mice.record2017PMID:291216752 findings
Astaxanthin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy via the ROS/MAPK Pathway in Mice.record2015PMID:260238422 findings
Astaxanthin supplementation delays physical exhaustion and prevents redox imbalances in plasma and soleus muscles of Wistar rats.record2014PMID:255145621 finding
Other names
11 names
Resolves to: astaxanthin
- Also called
- (3S,3'S)-astaxanthin3,3'-dihydroxy-beta-carotene-4,4'-dione3,3'-dihydroxy-beta,beta-carotene-4,4'-dione3,3'-dihydroxy-β-carotene-4,4'-dione3,3'-dihydroxy-β,β-carotene-4,4'-dioneall-trans-(3S,3'S)-astaxanthinastaxanthineE 161jovoester
- Systematic name
- (3S,3'S)-3,3'-dihydroxy-beta,beta-carotene-4,4'-dione(3S,3'S)-3,3'-dihydroxy-β,β-carotene-4,4'-dione