4-methylumbelliferyl acetate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

127 compounds within 3 steps: 2 in 1, 20 in 2, 105 in 3

Three steps

1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 more
1-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 moreOne of 4 routes
1-hexadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 moreOne of 3 routes
1-octadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 moreOne of 3 routes
4-acetamidobutanalReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-acetylputrescine + H2O = putrescine + acetate
3. N-Acetylputrescine:oxygen oxidoreductase(deaminating)(flavin-containing)
Catalysed by CES2, ESD, CES1, HDAC10 and 5 morecytosolOne of 2 routes
1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 moreOne of 8 routes
2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 moreOne of 2 routes
1-octadecanoyl-N-(acetyl)-sphing-4-enineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 moreOne of 5 routes
2-octadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-octadecanoyl-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 more
1-hexadecanoyl-N-(acetyl)-sphing-4-enineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 moreOne of 9 routes
2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 2-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 more
2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 moreOne of 2 routes
1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 moreOne of 3 routes
2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 more
2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 more
1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 moreOne of 3 routes
1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-N-(acetyl)-sphing-4-enineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 more
2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 more
2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 more
2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 more
16alpha,17alpha-dihydroxyprogesteroneReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. cytochrome P450 (17alpha-hydroxyprogesterone)
3. 17alpha-hydroxyprogesterone + reduced [NADPH--hemoprotein reductase] + O2 = 16alpha,17alpha-dihydroxyprogesterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by CES2, ESD, CES1, CYP17A1endoplasmic reticulum
2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-O-acyl-N-(acetyl)-sphing-4-enine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 more
2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 more
1-octadecanoyl-sn-glycero-3-phosphoserineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-sn-glycero-3-phosphoserine + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 more
1-O-acyl-N-(acetyl)-sphing-4-enineReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine
Catalysed by CES2, ESD, CES1, ASAH1 and 1 moreOne of 8 routes
N-(acetyl)-sphing-4-enine-1-phosphateReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. N-(acetyl)-sphing-4-enine + ATP = N-(acetyl)-sphing-4-enine-1-phosphate + ADP + H(+)
Catalysed by CES2, ESD, CES1, ASAH1 and 1 more
2-(1-hydroxyethyl)thiamine diphosphateReach from here →
1. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
2. transport of acetate and pyruvate (cytosol to extracellular)
3. pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating)
Catalysed by CES2, ESD, CES1, SLC16A4 and 7 moreextracellular space, cytosol, mitochondrial matrix