5,6-dihydrouracil

Three steps

• L-alanineReach from here →
  1. 5,6-Dihydrouracil amidohydrolase
  2. 3-ureidopropanoate amidohydrolase
  3. 3-oxopropanoate + L-alanine = beta-alanine + pyruvate

  Catalysed by DPYS, UPB1, AGXT2cytosolOne of 5 routes

• L-asparagineReach from here →
  1. 5,6-Dihydrouracil amidohydrolase
  2. Transport of 3-Ureidopropionate
  3. Transport of L-Asparagine by Atb0 Transporter

  Catalysed by DPYS, SLC6A14cytosol, extracellular spaceOne of 2 routes

• L-phenylalanineReach from here →
  1. 5,6-Dihydrouracil amidohydrolase
  2. Transport of 3-Ureidopropionate
  3. Transport of L-Phenylalanine by Atb0 Transporter

  Catalysed by DPYS, SLC6A14cytosol, extracellular spaceOne of 2 routes

• 4-aminobutanoateReach from here →
  1. 5,6-Dihydrouracil amidohydrolase
  2. Transport of 3-Ureidopropionate
  3. transport of 4-aminobutyrate and chloride (cytosol to extracellular)

  Catalysed by DPYS, SLC6A12cytosol, extracellular spaceOne of 4 routes