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Proteins/UNIPROT:Q14117
Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate.
Function from UniProtKB (Q14117), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
21 statements
21 statements · 8 reference databases · Subject: DPYS · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
3 reactions
5,6-dihydrouracil+waterN-carbamoyl-beta-alanine+proton
Catalysed by DPYS
Reaction pageLeft to rightBalancedEC 3.5.2.2cytosol
Human-GEM MAR04346CC BY 4.0Reference data
5,6-dihydrothymine+water3-(carbamoylamino)-2-methylpropanoate+proton
Catalysed by DPYS
Reaction pageLeft to rightBalancedEC 3.5.2.2cytosol
4 names
Resolves to: DPYS
5,6-dihydrouracil+water3-(carbamoylamino)propanoate+hydron
Catalysed by DPYS
Reaction pageDirection not assertedBalanced
Rhea RHEA:16121CC BY 4.0Reference data