arachidonoyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

783 compounds within 3 steps: 5 in 1, 199 in 2, 579 in 3

Three steps

a 1-acyl-2-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
1. Arachidonyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + octadecanoyl-CoA = a 1-acyl-2-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 9 morecytosol
cholesteryl (9Z)-hexadecenoateReach from here →
1. Arachidonyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (palmitolate)
3. (9Z)-hexadecenoyl-CoA + cholesterol = cholesteryl (9Z)-hexadecenoate + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
(9Z,12Z,15Z-octadecatrienoyl)-cholesterolReach from here →
1. Arachidonyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (linolenate)
3. (9Z,12Z,15Z)-octadecatrienoyl-CoA + cholesterol = (9Z,12Z,15Z-octadecatrienoyl)-cholesterol + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
cholesteryl (8Z,11Z,14Z)-eicosatrienoateReach from here →
1. Arachidonyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
3. Acyl-CoA:cholesterol O-acyltransferase
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosol, endoplasmic reticulumOne of 5 routes
1-heptadecanoyl-sn-glycero-3-phosphoserineReach from here →
1. Arachidonyl-CoA hydrolase
2. 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoserine + H2O = 1-heptadecanoyl-sn-glycero-3-phosphoserine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
3. 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoserine + H2O = 1-heptadecanoyl-sn-glycero-3-phosphoserine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 2 morecytosol
a monoacyl-sn-glycero-3-phosphocholineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a monoacyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)
Catalysed by LPGAT1, PNLIPRP2cytosol
2-(acylamino)ethyl fatty acidReach from here →
1. acyl-CoA pool formation and breakdown
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. an N-acylethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 2-(acylamino)ethyl fatty acid + a 2-acyl-sn-glycero-3-phosphocholine
Catalysed by LPGAT1, PLA2G15cytosolOne of 2 routes
1-O-acyl-N-(acetyl)-sphing-4-enineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine
Catalysed by LPGAT1, PLA2G15cytosolOne of 8 routes
1-heptadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. Arachidonyl-CoA hydrolase
2. 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 1-heptadecanoyl-sn-glycero-3-phosphoethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
3. 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 1-heptadecanoyl-sn-glycero-3-phosphoethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 2 morecytosol
O-tetradecanoyl-(R)-carnitineReach from here →
1. Arachidonyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. tetradecanoyl-CoA + (R)-carnitine = O-tetradecanoyl-(R)-carnitine + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
O-octadecanoyl-(R)-carnitineReach from here →
1. Arachidonyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. (R)-carnitine + octadecanoyl-CoA = O-octadecanoyl-(R)-carnitine + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 9 morecytosol
O-eicosanoyl-(R)-carnitineReach from here →
1. Arachidonyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. eicosanoyl-CoA + (R)-carnitine = O-eicosanoyl-(R)-carnitine + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
O-4,8-dimethylnonanoyl-(R)-carnitineReach from here →
1. Arachidonyl-CoA hydrolase
2. Utilized Transport
3. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 3 morecytosol, endoplasmic reticulum, peroxisomeOne of 7 routes
1,2-diacyl-sn-glycero-3-phosphoethanolReach from here →
1. acyl-CoA pool formation and breakdown
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. ethanol + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1,2-diacyl-sn-glycero-3-phosphoethanol + choline
Catalysed by LPGAT1, PLD1cytosol
1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholineReach from here →
1. Arachidonyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 9 morecytosol
1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholineReach from here →
1. Arachidonyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 9 morecytosol
(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-cholesterolReach from here →
1. Arachidonyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (EPA)
3. Acyl-CoA:cholesterol O-acyltransferase
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosol, endoplasmic reticulumOne of 6 routes
2-glyceryl-prostaglandin G2Reach from here →
1. Arachidonyl-CoA hydrolase
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 2 O2 = 2-glyceryl-prostaglandin G2
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 3 morecytosol
1-O-(9Z-octadecenyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphateReach from here →
1. Arachidonyl-CoA hydrolase
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + ATP + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate
3. 1-O-(9Z-octadecenyl)-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-O-(9Z-octadecenyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 13 morecytosol
N-tetradecanoylglycineReach from here →
1. Arachidonyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosolOne of 2 routes
N-eicosanoylglycinateReach from here →
1. Arachidonyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. eicosanoyl-CoA + glycine = N-eicosanoylglycinate + CoA + H(+)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 9 morecytosolOne of 2 routes
N-docosanoylglycineReach from here →
1. Arachidonyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (behenic acid)
3. docosanoyl-CoA + glycine = N-docosanoylglycine + CoA + H(+)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 9 morecytosolOne of 2 routes
N-hexacosanoylglycineReach from here →
1. Arachidonyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (cerotic acid)
3. hexacosanoyl-CoA + glycine = N-hexacosanoylglycine + CoA + H(+)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 9 morecytosolOne of 2 routes
(2E,5Z)-tetradecadienoyl-CoAReach from here →
1. Arachidonyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (physeteric acid)
3. medium-chain acyl-CoA dehydrogenase (5-tetradecenoyl-CoA)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 13 morecytosol, mitochondrial matrixOne of 4 routes
(2E,7Z)-hexadecadienoyl-CoAReach from here →
1. Arachidonyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)
3. medium-chain acyl-CoA dehydrogenase (7-hexadecenoyl-CoA)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 13 morecytosol, mitochondrial matrixOne of 4 routes
cholesteryl (11Z)-octadecenoateReach from here →
1. Arachidonyl-CoA hydrolase
2. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
3. (11Z)-octadecenoyl-CoA + cholesterol = cholesteryl (11Z)-octadecenoate + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 5 morecytosol
(5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. Arachidonyl-CoA hydrolase
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate
3. (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + 2 glutathione = (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + glutathione disulfide + H2O
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 8 morecytosol
(12S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoateReach from here →
1. Arachidonyl-CoA hydrolase
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate
3. (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + 2 glutathione = (12S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + glutathione disulfide + H2O
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 6 morecytosol
(12S)-hydroxy-(5Z,8E,10E)-heptadecatrienoateReach from here →
1. Arachidonyl-CoA hydrolase
2. prostaglandin-endoperoxide synthase (arachidonate)
3. prostaglandin H2 = (12S)-hydroxy-(5Z,8E,10E)-heptadecatrienoate + malonaldehyde
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 6 morecytosol
thromboxane B2Reach from here →
1. Arachidonyl-CoA hydrolase
2. transport of arachidonate (cytosol to extracellular)
3. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 2 morecytosol, extracellular spaceOne of 4 routes
11-oxo-(5Z,8Z,12E,14Z)-eicosatetraenoateReach from here →
1. Arachidonyl-CoA hydrolase
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + A + H2O
3. (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + NAD(+) = 11-oxo-(5Z,8Z,12E,14Z)-eicosatetraenoate + NADH + H(+)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 3 morecytosol
19-hydroxyprostaglandin H2Reach from here →
1. Arachidonyl-CoA hydrolase
2. prostaglandin-endoperoxide synthase (arachidonate)
3. prostaglandin H2 + reduced [NADPH--hemoprotein reductase] + O2 = 19-hydroxyprostaglandin H2 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 4 morecytosol
taurochenodeoxycholateReach from here →
1. Arachidonyl-CoA hydrolase
2. transport of arachidonate (cytosol to extracellular)
3. solute carrier organic anion transporter (S-glutathionyl-2-4-dinitrobenzene)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 5 morecytosol, extracellular spaceOne of 9 routes