Compound
calcitriol
No description recorded for this entry yet. Everything this graph holds about calcitriol is below.
Structure
- Class
- Organic compound
- Formula
- C27H44O3
- Mass
- 416.646 g/mol
- Charge
- 0
- InChIKey
- GMRQFYUYWCNGIN-NKMMMXOESA-N
- SMILES
- [H][C@@]12CC[C@]([H])([C@H](C)CCCC(C)(C)O)[C@@]1(C)CCC/C2=CC=C1C[C@@H](O)C[C@H](O)C1=C
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence — none of it carries a grade.
What it touches on the way
A finding says calcitriol moved an endpoint. This is the biology in between: the proteins and reactions it runs through to get there. It is where to look for the two things a list of findings cannot answer — why a result might happen, and what else acts on the same machinery.
4 of these are proteins with a page of their own, and that is the door: a protein page says what else it carries, which is how one compound leads to the next.
Mechanistic reach
4 entities
4 entities reached, most connected first. Hub metabolites are excluded, so this is not a claim that the compound touches everything.
0 reported hops4 assembled from the scaffold
What the reference databases state
The section above shows paths a projection assembled. This is the reference layer itself, one step from calcitriol: what the cleared databases state it reacts with, is carried by, is converted to and takes part in, whether or not a projection has walked it yet.
Regulatory determinations
Published numbers and scores, transcribed from the body that issued them. A determination is not a finding and is not graded; it is the number, who set it, and the document it came from.
LiverTox likelihood score ELiverTox
LiverTox Likelihood Score E — despite extensive use, no evidence that the agent has caused liver injury. Chapter: "Vitamin D". Source: LiverTox Master List (NBK571102).
The document·Public Domain (NLM/NIH)·Transcribed, not graded
Statements
13 statements
13 statements in 2 reference databases name calcitriol — Human-GEM, Rhea. Press a relation to see only its rows; every count is the rows behind it.
- calcitriol is metabolised by CYP24A1ProteinRhea RHEA:49192Inferred only
- calcitriol is metabolised by CYP24A1ProteinRhea RHEA:24964Inferred only
- calcitriol is metabolised by CYP27B1ProteinHuman-GEM MAR02118Inferred only
- calcitriol is metabolised by CYP27B1ProteinRhea RHEA:20573Inferred only
- calcitriol is metabolised by CYP27B1ProteinHuman-GEM MAR08008Inferred only
- calcitriol is metabolised by CYP2R1ProteinRhea RHEA:49272Inferred only
- calcitriol is metabolised by UGT1A4ProteinRhea RHEA:55836Inferred only
- calcitriol is a substrate of CUBNProteinHuman-GEM MAR02118Inferred only
- calcitriol is a substrate of CUBNProteinHuman-GEM MAR08008Inferred only
- calcitriol is a substrate of GCProteinHuman-GEM MAR08008Inferred only
- calcitriol is a substrate of GCProteinHuman-GEM MAR02118Inferred only
- calcitriol is a substrate of LRP2ProteinHuman-GEM MAR02118Inferred only
Show the remaining 1
- calcitriol is a substrate of LRP2ProteinHuman-GEM MAR08008Inferred only
Other names
18 names
Every name this graph resolves to calcitriol. Searching any of them lands here.
- Also called
- (1alpha,3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triol(1α,3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol(5Z,7E)-(1S,3R)-9,10-seco-5,7,10(19)-cholestatriene-1,3,25-triol(5Z,7E)-(1S,3R)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol1-alpha-25-Dihydroxyvitamin D31,25-DHCC1alpha,25-dihydroxycholecalciferol1alpha,25-dihydroxyvitamin D31alpha,25(OH)2D31α,25-dihydroxycholecalciferol1α,25-dihydroxyvitamin D31α,25(OH)2D35-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL
- Systematic name
- (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
- Sold as
- CalcijexDecostriolRocaltrol