Compound

calcitriol 25-O-(beta-D-glucuronide)

A steroid glucuronide anion that is the conjugate base of calcitriol 25-O-(β-D-glucuronide) arising from deprotonation of the carboxylic acid function; major species at pH 7.3.

Definition from ChEBI (CHEBI:139274), read 2026-09-23. CC BY 4.0.

CHEBI:139274ChEBI

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Structure

2D depiction · 3D model shown

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A generated conformer of calcitriol 25-O-(beta-D-glucuronide) — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C33H51O9
Mass: 591.762 g/mol
Charge: -1
InChIKey: UBEXJJQDSPZXNL-BHNPUNFPSA-M
SMILES: [H][C@@]12CC[C@]([H])([C@H](C)CCCC(C)(C)O[C@@H]3O[C@H](C(=O)[O-])[C@@H](O)[C@H](O)[C@H]3O)[C@@]1(C)CCC/C2=CC=C1C[C@@H](O)C[C@H](O)C1=C
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

1 entity

1 entities reached.

0 reported hops1 assembled from the scaffold

UGT1A4ProteinUNIPROT:P22310metabolized byInferred only23 paths23 endpoints

What the reference databases state

Chemical structure

calcitriol 25-O-(beta-D-glucuronide) has the functional parent calcitriolCompoundChEBI CHEBI:139274Inferred only

Statements

1 statement

1 statement · 1 reference database · Subject: calcitriol 25-O-(beta-D-glucuronide) · Sources: Rhea

Order

calcitriol 25-O-(beta-D-glucuronide) is metabolised by UGT1A4ProteinRhea RHEA:55836Inferred only

Reactions

1 reaction

calcitriol+UDP-alpha-D-glucuronatecalcitriol 25-O-(beta-D-glucuronide)+UDP+hydron
Catalysed by UGT1A4
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:55836CC BY 4.0Reference data

Other names

8 names

Resolves to: calcitriol 25-O-(beta-D-glucuronide)

Also called: (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3-diol-25-yl beta-D-glucopyranosiduronate(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3-diol-25-yl β-D-glucopyranosiduronate1alpha,25-dihydroxyvitamin D3 25-O-(beta-D-glucuronate)1alpha,25-dihydroxyvitamin D3 25-O-(beta-D-glucuronide)(1-)1α,25-dihydroxyvitamin D3 25-O-(β-D-glucuronate)1α,25-dihydroxyvitamin D3 25-O-(β-D-glucuronide)(1−)
Systematic name: (6R)-6-[(1R,3aS,4E,7aR)-4-{(2Z)-2-[(3S,5R)-3,5-dihydroxy-2-methylidenecyclohexylidene]ethylidene}-7a-methyloctahydro-1H-inden-1-yl]-2-methylheptan-2-yl beta-D-glucopyranosiduronate(6R)-6-[(1R,3aS,4E,7aR)-4-{(2Z)-2-[(3S,5R)-3,5-dihydroxy-2-methylidenecyclohexylidene]ethylidene}-7a-methyloctahydro-1H-inden-1-yl]-2-methylheptan-2-yl β-D-glucopyranosiduronate